DK398086A - Fremgangsmaade til foroegelse af oploeseligheden af immunokonjugatpraeparationer eller ukonjugeret immunoglobulin samt fremgangsmaade til nedsaettelse af intakte toksinkonjugaters toksicitet - Google Patents

Fremgangsmaade til foroegelse af oploeseligheden af immunokonjugatpraeparationer eller ukonjugeret immunoglobulin samt fremgangsmaade til nedsaettelse af intakte toksinkonjugaters toksicitet Download PDF

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Publication number
DK398086A
DK398086A DK398086A DK398086A DK398086A DK 398086 A DK398086 A DK 398086A DK 398086 A DK398086 A DK 398086A DK 398086 A DK398086 A DK 398086A DK 398086 A DK398086 A DK 398086A
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DK
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Prior art keywords
procedure
solubility
increasing
conjugators
toxicity
Prior art date
Application number
DK398086A
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English (en)
Other versions
DK398086D0 (da
Inventor
Jr A Charles Morgan
Gowsala Pavanasasivan
Original Assignee
Neorx Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neorx Corp filed Critical Neorx Corp
Publication of DK398086D0 publication Critical patent/DK398086D0/da
Publication of DK398086A publication Critical patent/DK398086A/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK398086A 1985-08-20 1986-08-20 Fremgangsmaade til foroegelse af oploeseligheden af immunokonjugatpraeparationer eller ukonjugeret immunoglobulin samt fremgangsmaade til nedsaettelse af intakte toksinkonjugaters toksicitet DK398086A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76749385A 1985-08-20 1985-08-20

Publications (2)

Publication Number Publication Date
DK398086D0 DK398086D0 (da) 1986-08-20
DK398086A true DK398086A (da) 1987-02-21

Family

ID=25079669

Family Applications (1)

Application Number Title Priority Date Filing Date
DK398086A DK398086A (da) 1985-08-20 1986-08-20 Fremgangsmaade til foroegelse af oploeseligheden af immunokonjugatpraeparationer eller ukonjugeret immunoglobulin samt fremgangsmaade til nedsaettelse af intakte toksinkonjugaters toksicitet

Country Status (7)

Country Link
EP (1) EP0213881B1 (da)
JP (1) JPS62181224A (da)
AT (1) ATE97324T1 (da)
CA (1) CA1306194C (da)
DE (1) DE3689299T2 (da)
DK (1) DK398086A (da)
NO (1) NO168989C (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4926869A (en) * 1986-01-16 1990-05-22 The General Hospital Corporation Method for the diagnosis and treatment of inflammation
US5162507A (en) * 1987-05-11 1992-11-10 Cetus Corporation Process for recovering purified, oxidized, renatured recombinant interleukin-2 from microorganisms
US4946675A (en) * 1987-05-27 1990-08-07 Xoma Corporation Hepatic blocking agents
CN104370997B (zh) * 2014-09-24 2018-07-31 陈辉 去除生物制品中细菌内毒素的试剂盒、方法及其生物制品的制备方法
EP4244625A1 (en) * 2020-11-13 2023-09-20 Beckman Coulter, Inc. Additives for reducing non-specific interactions between fluorescent polymer conjugates and cells in a biological sample

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2927103A1 (de) * 1978-10-06 1980-04-17 Baxter Travenol Lab Optisches verfahren zur bestimmung von endotoxin
US4460559A (en) * 1980-03-03 1984-07-17 Goldenberg Milton David Tumor localization and therapy with labeled antibodies specific to intracellular tumor-associated markers

Also Published As

Publication number Publication date
NO168989B (no) 1992-01-20
JPS62181224A (ja) 1987-08-08
EP0213881A3 (en) 1987-09-16
NO863338D0 (no) 1986-08-19
DK398086D0 (da) 1986-08-20
DE3689299D1 (de) 1993-12-23
ATE97324T1 (de) 1993-12-15
DE3689299T2 (de) 1994-03-10
EP0213881A2 (en) 1987-03-11
CA1306194C (en) 1992-08-11
NO168989C (no) 1992-04-29
NO863338L (no) 1987-02-23
EP0213881B1 (en) 1993-11-18

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment