DK388188A - 1h-pyrazol-1-alkanamider med antiarrhythmisk virkning og fremgangsmaade til fremstilling af saadanne forbindelser - Google Patents

1h-pyrazol-1-alkanamider med antiarrhythmisk virkning og fremgangsmaade til fremstilling af saadanne forbindelser

Info

Publication number
DK388188A
DK388188A DK388188A DK388188A DK388188A DK 388188 A DK388188 A DK 388188A DK 388188 A DK388188 A DK 388188A DK 388188 A DK388188 A DK 388188A DK 388188 A DK388188 A DK 388188A
Authority
DK
Denmark
Prior art keywords
alkanamides
pyrazol
preparing
compounds
procedure
Prior art date
Application number
DK388188A
Other languages
Danish (da)
English (en)
Other versions
DK388188D0 (da
Inventor
Denis Mahlon Bailey
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of DK388188D0 publication Critical patent/DK388188D0/da
Publication of DK388188A publication Critical patent/DK388188A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18One oxygen or sulfur atom
    • C07D231/20One oxygen atom attached in position 3 or 5
    • C07D231/22One oxygen atom attached in position 3 or 5 with aryl radicals attached to ring nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK388188A 1987-07-13 1988-07-12 1h-pyrazol-1-alkanamider med antiarrhythmisk virkning og fremgangsmaade til fremstilling af saadanne forbindelser DK388188A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7249087A 1987-07-13 1987-07-13
US20624688A 1988-06-13 1988-06-13

Publications (2)

Publication Number Publication Date
DK388188D0 DK388188D0 (da) 1988-07-12
DK388188A true DK388188A (da) 1989-01-16

Family

ID=26753416

Family Applications (1)

Application Number Title Priority Date Filing Date
DK388188A DK388188A (da) 1987-07-13 1988-07-12 1h-pyrazol-1-alkanamider med antiarrhythmisk virkning og fremgangsmaade til fremstilling af saadanne forbindelser

Country Status (13)

Country Link
EP (1) EP0299407B1 (ja)
JP (1) JPS6463573A (ja)
AU (1) AU599251B2 (ja)
DE (1) DE3860878D1 (ja)
DK (1) DK388188A (ja)
ES (1) ES2039514T3 (ja)
FI (1) FI883315A (ja)
GR (1) GR3001361T3 (ja)
IL (1) IL86926A (ja)
NO (1) NO883114L (ja)
NZ (1) NZ225272A (ja)
PH (1) PH24914A (ja)
PT (1) PT87974B (ja)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4962120A (en) * 1989-03-22 1990-10-09 Sterling Drug Inc. 1H-imidazole-1-acetamides
US4888352A (en) * 1989-03-22 1989-12-19 Sterling Drug Inc. 3,4, or 5-aryl-1H-pyrazole-1-alkanamides as antiarrhythmic agents, compositions and use
US4925857A (en) * 1989-03-22 1990-05-15 Sterling Drug Inc. Pyridinyl-1H-pyrazole-1-alkanamides as antiarrhythmic agents
US4898880A (en) * 1989-03-22 1990-02-06 Sterling Drug Inc. N-(heterocycle)alkyl)-1H-pyrazole-1-alkanamides as antiarrhythmic agents, compositions and use
US4916150A (en) * 1989-03-22 1990-04-10 Sterling Drug Inc. 1H-pyrazole-1-alkanamines antiarrhythmic compositions and use
US4994482A (en) * 1989-07-31 1991-02-19 Bristol-Myers Squibb Company Arylpyrazol derivatives as anti-platelet agents, compositions and use
FR2773153A1 (fr) * 1997-12-29 1999-07-02 Rhone Poulenc Agrochimie Nouveaux composes fongicides
EP1542680B1 (en) * 2002-09-09 2007-03-07 Amgen Inc. 1, 4, 5-substituted 1, 2-dihydro-pyrazol-3-one and 3-alkoxy-1h-pyrazole derivatives as tnf-alpha and interleukin lowering agents for the treatment of inflammations

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4182895A (en) * 1976-12-20 1980-01-08 Sterling Drug Inc. 1-Amino-lower-alkyl-3,4-diphenyl-1H-pyrazoles
CH633677A5 (en) * 1977-03-28 1982-12-31 Ciba Geigy Ag Microbicidal composition, process for the preparation of the active compound and its use for the control of phytopathogenic fungi
DE3126083A1 (de) * 1981-07-02 1983-01-20 Basf Ag, 6700 Ludwigshafen N-substituierte 2-methylnaphthylamide, verfahren zu ihrer herstellung und diese enthaltende fungizide
DE3424586A1 (de) * 1984-07-04 1986-01-09 Kali-Chemie Pharma Gmbh, 3000 Hannover 3-aminocarbonylmethoxy-5-phenyl-pyrazol-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
PH24914A (en) 1990-12-26
NO883114D0 (no) 1988-07-12
EP0299407A1 (en) 1989-01-18
AU1893088A (en) 1989-01-19
IL86926A0 (en) 1988-11-30
ES2039514T3 (es) 1993-10-01
GR3001361T3 (en) 1992-09-11
NZ225272A (en) 1991-09-25
FI883315A0 (fi) 1988-07-12
EP0299407B1 (en) 1990-10-24
NO883114L (no) 1989-01-16
JPS6463573A (en) 1989-03-09
DK388188D0 (da) 1988-07-12
FI883315A (fi) 1989-01-14
DE3860878D1 (de) 1990-11-29
AU599251B2 (en) 1990-07-12
IL86926A (en) 1992-07-15
PT87974A (pt) 1989-06-30
PT87974B (pt) 1995-03-01

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment