DK3856711T3 - Syntetisk fremgangsmåde til fremstillingen af en hydrazinforbindelse - Google Patents

Syntetisk fremgangsmåde til fremstillingen af en hydrazinforbindelse Download PDF

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Publication number
DK3856711T3
DK3856711T3 DK19780306.7T DK19780306T DK3856711T3 DK 3856711 T3 DK3856711 T3 DK 3856711T3 DK 19780306 T DK19780306 T DK 19780306T DK 3856711 T3 DK3856711 T3 DK 3856711T3
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DK
Denmark
Prior art keywords
preparation
synthetic procedure
hydrazine compound
hydrazine
compound
Prior art date
Application number
DK19780306.7T
Other languages
Danish (da)
English (en)
Inventor
Yunzhong Li
Xiaobin Jiang
Niek Johannes Ronde
Carmen Ruiz
Jerome Dauvergne
Original Assignee
Mereo Biopharma 1 Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mereo Biopharma 1 Ltd filed Critical Mereo Biopharma 1 Ltd
Application granted granted Critical
Publication of DK3856711T3 publication Critical patent/DK3856711T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C241/00—Preparation of compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C241/02—Preparation of hydrazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/10—Hydrazines
    • C07C243/22—Hydrazines having nitrogen atoms of hydrazine groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/56—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and doubly-bound oxygen atoms bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK19780306.7T 2018-09-26 2019-09-26 Syntetisk fremgangsmåde til fremstillingen af en hydrazinforbindelse DK3856711T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1815696.8A GB201815696D0 (en) 2018-09-26 2018-09-26 Synthetic method
PCT/GB2019/052719 WO2020065324A1 (en) 2018-09-26 2019-09-26 Synthetic method for the preparation of an hydrazine compound

Publications (1)

Publication Number Publication Date
DK3856711T3 true DK3856711T3 (da) 2022-12-12

Family

ID=64024292

Family Applications (1)

Application Number Title Priority Date Filing Date
DK19780306.7T DK3856711T3 (da) 2018-09-26 2019-09-26 Syntetisk fremgangsmåde til fremstillingen af en hydrazinforbindelse

Country Status (12)

Country Link
US (1) US20210340108A1 (enExample)
EP (1) EP3856711B1 (enExample)
JP (1) JP2022502415A (enExample)
KR (1) KR20210065111A (enExample)
CN (1) CN112839923A (enExample)
AU (1) AU2019349863A1 (enExample)
CA (1) CA3112998A1 (enExample)
DK (1) DK3856711T3 (enExample)
ES (1) ES2933568T3 (enExample)
GB (1) GB201815696D0 (enExample)
IL (1) IL281637A (enExample)
WO (1) WO2020065324A1 (enExample)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2732967B1 (fr) * 1995-04-11 1997-07-04 Sanofi Sa 1-phenylpyrazole-3-carboxamides substitues, actifs sur la neurotensine, leur preparation, les compositions pharmaceutiques en contenant
CN1832928B (zh) * 2003-06-26 2012-07-04 诺瓦提斯公司 以5元杂环为基础的p38激酶抑制剂
CN1326029C (zh) * 2003-07-10 2007-07-11 富士施乐株式会社 印刷装置、印刷指示装置、印刷处理系统及印刷处理方法
US7485657B2 (en) * 2004-05-12 2009-02-03 Boehringer Ingelheim Pharmaceuticals, Inc. Anti-cytokine heterocyclic compounds
US20100292290A1 (en) * 2007-08-02 2010-11-18 Vinayak Gore Novel process to prepare almotriptan
CN101910139B (zh) * 2008-01-10 2012-09-26 北兴化学工业株式会社 苯基三唑啉酮类的制造方法
JP5602387B2 (ja) * 2008-05-02 2014-10-08 キヤノン株式会社 インクジェット用インク、インクジェット記録方法、インクカートリッジ、記録ユニット、及びインクジェット記録装置
CN102964270B (zh) * 2012-11-21 2015-01-07 合肥星宇化学有限责任公司 一种亚硫酸钠还原重氮盐合成肼的方法
JP2016204436A (ja) * 2015-04-17 2016-12-08 日本化薬株式会社 水溶性アゾ化合物又はその塩、インク組成物及び着色体
WO2018059533A1 (zh) * 2016-09-29 2018-04-05 南京明德新药研发股份有限公司 p38αMAPK激酶抑制剂及其制备方法和应用

Also Published As

Publication number Publication date
GB201815696D0 (en) 2018-11-07
EP3856711A1 (en) 2021-08-04
IL281637A (en) 2021-05-31
CN112839923A (zh) 2021-05-25
ES2933568T3 (es) 2023-02-10
JP2022502415A (ja) 2022-01-11
KR20210065111A (ko) 2021-06-03
CA3112998A1 (en) 2020-04-02
EP3856711B1 (en) 2022-11-16
WO2020065324A1 (en) 2020-04-02
US20210340108A1 (en) 2021-11-04
AU2019349863A1 (en) 2021-04-15

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