DK3826723T3 - Boronsyrederivater - Google Patents

Boronsyrederivater Download PDF

Info

Publication number
DK3826723T3
DK3826723T3 DK19742212.4T DK19742212T DK3826723T3 DK 3826723 T3 DK3826723 T3 DK 3826723T3 DK 19742212 T DK19742212 T DK 19742212T DK 3826723 T3 DK3826723 T3 DK 3826723T3
Authority
DK
Denmark
Prior art keywords
acid derivatives
boronic acid
boronic
derivatives
acid
Prior art date
Application number
DK19742212.4T
Other languages
English (en)
Inventor
Markus Klein
Oliver Schadt
Philipp Haselmayer
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Application granted granted Critical
Publication of DK3826723T3 publication Critical patent/DK3826723T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • C07F5/025Boronic and borinic acid compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/69Boron compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK19742212.4T 2018-07-26 2019-07-23 Boronsyrederivater DK3826723T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18185848 2018-07-26
PCT/EP2019/069744 WO2020020858A1 (en) 2018-07-26 2019-07-23 Boronic acid derivatives

Publications (1)

Publication Number Publication Date
DK3826723T3 true DK3826723T3 (da) 2024-01-15

Family

ID=63077806

Family Applications (1)

Application Number Title Priority Date Filing Date
DK19742212.4T DK3826723T3 (da) 2018-07-26 2019-07-23 Boronsyrederivater

Country Status (15)

Country Link
US (1) US20210317145A1 (da)
EP (1) EP3826723B1 (da)
JP (1) JP2021531310A (da)
KR (1) KR20210038590A (da)
CN (1) CN112469480A (da)
AU (1) AU2019310779A1 (da)
BR (1) BR112021001359A2 (da)
CA (1) CA3107377A1 (da)
DK (1) DK3826723T3 (da)
ES (1) ES2968443T3 (da)
IL (1) IL280376B1 (da)
MX (1) MX2021000214A (da)
SG (1) SG11202100727VA (da)
TW (1) TW202019436A (da)
WO (1) WO2020020858A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114075227B (zh) * 2020-08-19 2023-07-04 北京嵩润医药科技有限责任公司 吡唑硼酸类化合物、包含其的药物组合物及它们的用途
TW202237143A (zh) * 2020-12-10 2022-10-01 南韓商Lg化學股份有限公司 酸(Boronic Acid)化合物
WO2023061445A1 (zh) * 2021-10-14 2023-04-20 首药控股(北京)股份有限公司 硼酸衍生物
WO2023107470A1 (en) * 2021-12-06 2023-06-15 Pretzel Therapeutics, Inc. Lonp1 inhibitors, uses and methods

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090325903A1 (en) 2008-06-17 2009-12-31 Millennium Pharmaceuticals, Inc. Boronate ester compounds and pharmaceutical compositions thereof
MX352652B (es) 2011-12-22 2017-12-04 Ares Trading Sa Inhibidores de inmunoproteasoma selectivos de derivados del acido alfa-amino boronico.
EP2819673B1 (en) 2012-03-02 2016-09-07 Dr. Reddy's Laboratories Ltd. Pharmaceutical compositions comprising boronic acid compounds
MX370336B (es) * 2014-10-01 2019-12-10 Merck Patent Gmbh Derivados de acido boronico.
CA2963198A1 (en) * 2014-10-01 2016-04-07 Merck Patent Gmbh Boronic acid derivatives
WO2016050355A1 (en) 2014-10-01 2016-04-07 Merck Patent Gmbh Boronic acid derivatives
SG11201702628XA (en) * 2014-10-01 2017-04-27 Merck Patent Gmbh Boronic acid derivatives
CN110540547A (zh) * 2018-05-28 2019-12-06 秦艳茹 一种肽硼酸酯类化合物的合成与用途

Also Published As

Publication number Publication date
MX2021000214A (es) 2021-03-31
JP2021531310A (ja) 2021-11-18
CA3107377A1 (en) 2020-01-30
SG11202100727VA (en) 2021-02-25
US20210317145A1 (en) 2021-10-14
EP3826723B1 (en) 2023-10-18
ES2968443T3 (es) 2024-05-09
IL280376B1 (en) 2024-04-01
BR112021001359A2 (pt) 2021-04-20
CN112469480A (zh) 2021-03-09
AU2019310779A1 (en) 2021-03-18
KR20210038590A (ko) 2021-04-07
EP3826723A1 (en) 2021-06-02
IL280376A (en) 2021-03-01
WO2020020858A1 (en) 2020-01-30
TW202019436A (zh) 2020-06-01

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