DK3768825T3 - Biosensor til mandlig infertilitet - Google Patents

Biosensor til mandlig infertilitet Download PDF

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Publication number
DK3768825T3
DK3768825T3 DK19759542.4T DK19759542T DK3768825T3 DK 3768825 T3 DK3768825 T3 DK 3768825T3 DK 19759542 T DK19759542 T DK 19759542T DK 3768825 T3 DK3768825 T3 DK 3768825T3
Authority
DK
Denmark
Prior art keywords
biosensor
male infertility
infertility
male
Prior art date
Application number
DK19759542.4T
Other languages
Danish (da)
English (en)
Inventor
Mohamad Takwa
Kushagr Punyani
Sudha Srivastava
Original Assignee
Spermosens Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spermosens Ab filed Critical Spermosens Ab
Application granted granted Critical
Publication of DK3768825T3 publication Critical patent/DK3768825T3/da

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0608—Germ cells
    • C12N5/0612—Germ cells sorting of gametes, e.g. according to sex or motility
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G01N27/3277—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction being a redox reaction, e.g. detection by cyclic voltammetry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Electrochemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Engineering & Computer Science (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DK19759542.4T 2018-08-24 2019-08-23 Biosensor til mandlig infertilitet DK3768825T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18190720 2018-08-24
PCT/EP2019/072574 WO2020039064A1 (en) 2018-08-24 2019-08-23 Biosensor for male infertility

Publications (1)

Publication Number Publication Date
DK3768825T3 true DK3768825T3 (da) 2021-09-20

Family

ID=63405057

Family Applications (1)

Application Number Title Priority Date Filing Date
DK19759542.4T DK3768825T3 (da) 2018-08-24 2019-08-23 Biosensor til mandlig infertilitet

Country Status (16)

Country Link
US (3) US20210325370A1 (enExample)
EP (1) EP3768825B1 (enExample)
JP (1) JP7168265B2 (enExample)
KR (1) KR102594453B1 (enExample)
CN (1) CN112639078B (enExample)
AU (1) AU2019325300B2 (enExample)
BR (1) BR112021001488A2 (enExample)
DK (1) DK3768825T3 (enExample)
EA (1) EA202190166A1 (enExample)
ES (1) ES2889973T3 (enExample)
IL (1) IL280445B2 (enExample)
MX (1) MX2021002145A (enExample)
PL (1) PL3768825T3 (enExample)
SG (1) SG11202100358VA (enExample)
WO (1) WO2020039064A1 (enExample)
ZA (1) ZA202100472B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022109378A1 (en) * 2020-11-23 2022-05-27 The University Of Toledo Quantification of sperm centriole quality
EP4713691A1 (en) * 2023-05-16 2026-03-25 Technion Research & Development Foundation Limited Method of determining fusogenic potential of sperm and use thereof in assisted fertilization and drug screening
CN116773427B (zh) * 2023-07-25 2026-06-19 香港大学深圳医院 通过流式细胞术检测精子体外受精能力的方法
CN120741585B (zh) * 2025-08-28 2025-11-11 华中科技大学 一种精子质量检测传感器及其制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7019114B2 (en) 1998-02-19 2006-03-28 Eastern Virginia Medical School Recombinant, biologically active human zona pellucida protein 3 (HZP3) to test male fertility
US6649419B1 (en) * 2000-11-28 2003-11-18 Large Scale Proteomics Corp. Method and apparatus for protein manipulation
WO2003011118A2 (en) 2001-08-02 2003-02-13 Trinity Biomedical Technology Corporation Human zona pellucida proteins and methods of their use in diagnosing male infertility
US8076090B2 (en) * 2005-04-05 2011-12-13 Corning Incorporated Label free biosensors and cells
WO2008026906A1 (es) * 2006-08-25 2008-03-06 Instituto Nacional De Ciencias Médicas Y Nutrición Salvador Zubirán Ensayo de captura de espermatozoides utilizando las proteinas zp2, zp3 y zp4
WO2009116051A1 (en) * 2008-03-20 2009-09-24 Tidhar Zanbar Method and kit for diagnosis of male fertility
WO2013012749A2 (en) 2011-07-15 2013-01-24 The Curators Of The University Of Missouri Human zona pellucida glycoproteins, their oligosaccharides, and uses thereof
WO2013122265A1 (ja) * 2012-02-17 2013-08-22 独立行政法人産業技術総合研究所 男性不妊症の原因因子検出方法及び男性不妊症モデル動物
RU2487705C1 (ru) * 2012-03-21 2013-07-20 ОКТАПАМ Лимитед Средство для улучшения репродуктивной функции
EP3066455B1 (en) * 2013-11-04 2019-08-14 Agency For Science, Technology And Research Optical sensing device for surface plasmon resonance (spr) and optical sensing method using surface plasmon resonance (spr)
CN106033086B (zh) 2015-03-17 2018-03-09 中国科学院宁波材料技术与工程研究所 基于lspr检测精子顶体酶活性的方法、试剂盒及其应用
US20170219554A1 (en) * 2016-01-29 2017-08-03 Mara Nanotech New York, Inc. Apparatus and method for detecting analytes in solution
CN108152189B (zh) * 2017-12-06 2020-06-05 浙江大学 一种精子表面出云蛋白1的定量检测方法

Also Published As

Publication number Publication date
CN112639078A (zh) 2021-04-09
US20210325370A1 (en) 2021-10-21
ES2889973T3 (es) 2022-01-14
US11782052B2 (en) 2023-10-10
MX2021002145A (es) 2021-04-28
AU2019325300A1 (en) 2021-04-15
CN112639078B (zh) 2025-11-07
IL280445A (en) 2021-03-01
SG11202100358VA (en) 2021-04-29
KR102594453B1 (ko) 2023-10-25
JP2021535366A (ja) 2021-12-16
ZA202100472B (en) 2022-07-27
IL280445B2 (en) 2025-11-01
KR20210049134A (ko) 2021-05-04
IL280445B1 (en) 2025-07-01
PL3768825T3 (pl) 2021-12-06
WO2020039064A1 (en) 2020-02-27
US20250306010A1 (en) 2025-10-02
EA202190166A1 (ru) 2021-05-28
EP3768825A1 (en) 2021-01-27
JP7168265B2 (ja) 2022-11-09
US20220026413A1 (en) 2022-01-27
AU2019325300B2 (en) 2023-10-05
BR112021001488A2 (pt) 2021-04-27
CA3109529A1 (en) 2020-02-27
EP3768825B1 (en) 2021-08-11

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