DK3744316T3 - Oftalmisk farmaceutisk sammensætning, fremgangsmåde til fremstilling deraf og anvendelse deraf - Google Patents

Oftalmisk farmaceutisk sammensætning, fremgangsmåde til fremstilling deraf og anvendelse deraf Download PDF

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Publication number
DK3744316T3
DK3744316T3 DK19743390.7T DK19743390T DK3744316T3 DK 3744316 T3 DK3744316 T3 DK 3744316T3 DK 19743390 T DK19743390 T DK 19743390T DK 3744316 T3 DK3744316 T3 DK 3744316T3
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DK
Denmark
Prior art keywords
preparation
pharmaceutical composition
ophthalmic pharmaceutical
ophthalmic
composition
Prior art date
Application number
DK19743390.7T
Other languages
English (en)
Inventor
Zuguo Liu
Yufen Zhao
Caihong Huang
Yang Wu
Guo Tang
Yan Liu
Pengxiang Xu
Original Assignee
Seinda Pharmaceutical Guangzhou Corp
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Application filed by Seinda Pharmaceutical Guangzhou Corp filed Critical Seinda Pharmaceutical Guangzhou Corp
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Publication of DK3744316T3 publication Critical patent/DK3744316T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05Dipeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/04Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK19743390.7T 2018-01-23 2019-01-22 Oftalmisk farmaceutisk sammensætning, fremgangsmåde til fremstilling deraf og anvendelse deraf DK3744316T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201810063904.7A CN108785251B (zh) 2018-01-23 2018-01-23 一种眼用药物组合物及其制备方法和应用
PCT/CN2019/072664 WO2019144863A1 (zh) 2018-01-23 2019-01-22 一种眼用药物组合物及其制备方法和应用

Publications (1)

Publication Number Publication Date
DK3744316T3 true DK3744316T3 (da) 2023-10-16

Family

ID=64094622

Family Applications (1)

Application Number Title Priority Date Filing Date
DK19743390.7T DK3744316T3 (da) 2018-01-23 2019-01-22 Oftalmisk farmaceutisk sammensætning, fremgangsmåde til fremstilling deraf og anvendelse deraf

Country Status (21)

Country Link
US (2) US20210030833A1 (da)
EP (2) EP4279063A3 (da)
JP (2) JP7418351B2 (da)
KR (1) KR20200113243A (da)
CN (2) CN112516080B (da)
AU (1) AU2019212565A1 (da)
BR (1) BR112020014950A2 (da)
CA (1) CA3089344A1 (da)
DK (1) DK3744316T3 (da)
ES (1) ES2960069T3 (da)
FI (1) FI3744316T3 (da)
HR (1) HRP20231069T1 (da)
HU (1) HUE063566T2 (da)
IL (1) IL276244A (da)
LT (1) LT3744316T (da)
PL (1) PL3744316T3 (da)
PT (1) PT3744316T (da)
RS (1) RS64732B1 (da)
SG (1) SG11202007077YA (da)
SI (1) SI3744316T1 (da)
WO (1) WO2019144863A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112516080B (zh) * 2018-01-23 2023-09-19 盛元医药广州有限公司 一种眼用药物组合物及其制备方法和应用
CN109771370B (zh) * 2019-02-28 2021-03-30 厦门大学 一种眼内手术用前房灌注液及其用途
CN113171340B (zh) * 2021-05-07 2022-12-06 四川科伦药业股份有限公司 一种丙氨酰谷氨酰胺注射液及其生产工艺
WO2023098537A1 (zh) * 2021-12-01 2023-06-08 盛元医药广州有限公司 丙谷二肽的新用途和包含丙谷二肽的眼用组合物
CN114869873A (zh) * 2022-05-05 2022-08-09 陈小鸟 谷氨酰胺在制备治疗干眼症的药物中的应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0455596B1 (de) * 1990-05-04 1994-11-02 Novartis AG Substituierte Indole
EP0539329A1 (de) * 1991-10-25 1993-04-28 Ciba-Geigy Ag Acetylen-Verbindungen, verwendbar als Leukotrien-Antagonisten
GB9419011D0 (en) * 1994-09-21 1994-11-09 Peptech Uk Ltd Use of muramyl peptide compounds
WO2002090380A1 (en) * 2001-04-17 2002-11-14 Sankt-Peterburgskaya Obschestvennaya Organizatsiya 'institut Bioregulyatsii I Gerontologii Czo Ramn' Tetrapeptide stimulating the retinal function and the method of its application
JP2006504701A (ja) 2002-09-30 2006-02-09 マーク・エー・バビザイェフ 眼疾患の局所的治療方法、並びに、その治療用組成物及び治療用手段
US20050089547A1 (en) * 2003-09-26 2005-04-28 Josef Neu Arginyl-glutamine dipeptide for treatment of pathological vascular proliferation
US8629099B2 (en) * 2008-03-25 2014-01-14 Bausch & Lomb Incorporated Ophthalmic compositions comprising a dipeptide
WO2010107069A1 (ja) * 2009-03-17 2010-09-23 千寿製薬株式会社 アミノ酸含有眼科用組成物
EP2478010B1 (en) * 2009-09-16 2014-08-06 Senju Pharmaceutical Co., Ltd. Partial peptide of lacritin
TW201225972A (en) 2010-11-15 2012-07-01 Univ Ramot Dipeptide analogs for treating conditions associated with amyloid fibril formation
US20130225684A1 (en) * 2012-02-28 2013-08-29 Kyowa Hakko Bio Co., Ltd. Methods and compositions for enhancement of vision performance
RU2498570C1 (ru) * 2012-05-03 2013-11-20 Государственное бюджетное учреждение "Уфимский научно-исследовательский институт глазных болезней Академии наук Республики Башкортостан" Раствор для хранения роговицы
EP3262060B1 (en) * 2015-02-25 2019-12-25 MacKay Memorial Hospital Peptides for use in the prevention and treatment of dry eye
CN107049938B (zh) * 2017-05-11 2021-01-05 艾迈德(厦门)生物科技有限公司 一种用于治疗干眼的滴眼液
CN112516080B (zh) * 2018-01-23 2023-09-19 盛元医药广州有限公司 一种眼用药物组合物及其制备方法和应用

Also Published As

Publication number Publication date
SI3744316T1 (sl) 2024-01-31
JP2024045187A (ja) 2024-04-02
JP2021512172A (ja) 2021-05-13
EP3744316A4 (en) 2021-12-08
CN108785251B (zh) 2020-11-24
EP4279063A3 (en) 2024-02-14
US20210030833A1 (en) 2021-02-04
FI3744316T3 (fi) 2023-09-12
ES2960069T3 (es) 2024-02-29
EP3744316B1 (en) 2023-08-30
IL276244A (en) 2020-09-30
AU2019212565A1 (en) 2020-08-13
EP4279063A2 (en) 2023-11-22
HRP20231069T1 (hr) 2023-12-22
CN112516080B (zh) 2023-09-19
RS64732B1 (sr) 2023-11-30
JP7418351B2 (ja) 2024-01-19
CN112516080A (zh) 2021-03-19
HUE063566T2 (hu) 2024-01-28
RU2020127883A (ru) 2022-02-24
EP3744316A1 (en) 2020-12-02
CA3089344A1 (en) 2019-08-01
KR20200113243A (ko) 2020-10-06
SG11202007077YA (en) 2020-08-28
CN108785251A (zh) 2018-11-13
US20240148818A1 (en) 2024-05-09
WO2019144863A1 (zh) 2019-08-01
LT3744316T (lt) 2023-11-10
PL3744316T3 (pl) 2024-04-15
BR112020014950A2 (pt) 2020-12-08
PT3744316T (pt) 2023-09-20

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