DK373181A - Fremgangsmaade til fremstilling af vincaminsaccharinat - Google Patents
Fremgangsmaade til fremstilling af vincaminsaccharinatInfo
- Publication number
- DK373181A DK373181A DK373181A DK373181A DK373181A DK 373181 A DK373181 A DK 373181A DK 373181 A DK373181 A DK 373181A DK 373181 A DK373181 A DK 373181A DK 373181 A DK373181 A DK 373181A
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- vincamine
- sacharinate
- vincamin
- procedure
- Prior art date
Links
- RXPRRQLKFXBCSJ-GIVPXCGWSA-N vincamine Chemical compound C1=CC=C2C(CCN3CCC4)=C5[C@@H]3[C@]4(CC)C[C@](O)(C(=O)OC)N5C2=C1 RXPRRQLKFXBCSJ-GIVPXCGWSA-N 0.000 title abstract 10
- RXPRRQLKFXBCSJ-UHFFFAOYSA-N dl-Vincamin Natural products C1=CC=C2C(CCN3CCC4)=C5C3C4(CC)CC(O)(C(=O)OC)N5C2=C1 RXPRRQLKFXBCSJ-UHFFFAOYSA-N 0.000 title abstract 5
- WKACQPMBGWZDMR-UHFFFAOYSA-N Vincamin Natural products CC=C1/CN2CCC34CC2C1C(=C3Nc5ccccc45)C=O WKACQPMBGWZDMR-UHFFFAOYSA-N 0.000 title 1
- CVHZOJJKTDOEJC-UHFFFAOYSA-M 1,1-dioxo-1,2-benzothiazol-3-olate Chemical compound C1=CC=C2C([O-])=NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-M 0.000 abstract 4
- 229960002726 vincamine Drugs 0.000 abstract 4
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- BDWFYHUDXIDTIU-UHFFFAOYSA-N ethanol;propane-1,2,3-triol Chemical compound CCO.OCC(O)CO BDWFYHUDXIDTIU-UHFFFAOYSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
- C07D275/06—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to the ring sulfur atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3031953 | 1980-08-25 | ||
| DE3031953 | 1980-08-25 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK373181A true DK373181A (da) | 1982-02-26 |
| DK151806B DK151806B (da) | 1988-01-04 |
| DK151806C DK151806C (da) | 1988-06-06 |
Family
ID=6110316
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK373181A DK151806C (da) | 1980-08-25 | 1981-08-24 | Analogifremgangsmaade til fremstilling af vincaminsaccharinat |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4362730A (da) |
| EP (1) | EP0046506B1 (da) |
| JP (1) | JPS5775982A (da) |
| KR (1) | KR840000702B1 (da) |
| AT (1) | ATE7698T1 (da) |
| DE (1) | DE3163875D1 (da) |
| DK (1) | DK151806C (da) |
| FI (1) | FI71319C (da) |
| GR (1) | GR75738B (da) |
| HU (1) | HU187626B (da) |
| IE (1) | IE51568B1 (da) |
| YU (1) | YU42246B (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4460560A (en) * | 1982-06-18 | 1984-07-17 | University Of Southern California | Drug delivery by polymeric carriers |
| CH663789A5 (it) * | 1985-08-27 | 1988-01-15 | Arysearch Arylan Ag | Procedimento per la produzione del sale 2-chetoglutarato di vincamina. |
| ES2097703B1 (es) * | 1995-04-12 | 1997-12-01 | Decox S L | Una nueva composicion estimulante de la actividad cerebral basada en alcaloides de nucleo de eburnamenina, y sus metodos de preparacion. |
| CN1202815C (zh) * | 1999-08-31 | 2005-05-25 | 格吕伦塔尔有限公司 | 含有曲马朵糖精盐的持续释放给药剂型 |
| US20050176790A1 (en) | 2001-02-28 | 2005-08-11 | Johannes Bartholomaus | Pharmaceutical salts |
| DE10109763A1 (de) * | 2001-02-28 | 2002-09-05 | Gruenenthal Gmbh | Pharmazeutische Salze |
| DE10130504B4 (de) | 2001-06-25 | 2005-02-03 | Nutrinova Nutrition Specialties & Food Ingredients Gmbh | Xanthin- und Phenazon-Acesulfam-H-Komplexe mit verbessertem Geschmack, Verfahren zu ihrer Herstellung und ihre Verwendung |
| EP2220098A2 (en) * | 2007-12-12 | 2010-08-25 | Ultimorphix Technologies B.v. | Solid forms of tenofovir disoproxil |
| US7935817B2 (en) * | 2008-03-31 | 2011-05-03 | Apotex Pharmachem Inc. | Salt form and cocrystals of adefovir dipivoxil and processes for preparation thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2134714A (en) * | 1936-11-25 | 1938-11-01 | Jacob A Glassman | Saccharine-aspirin tablet |
| US2538645A (en) * | 1948-10-18 | 1951-01-16 | William F Hamilton | Vasoconstrictor compounds of saccharin and pharmaceutical compositions produced therefrom |
| FR2193586A1 (en) * | 1972-07-31 | 1974-02-22 | Centre Etd Ind Pharma | Vincamine dioctyl sulphosuccinate for medical use - for humans and animals as a cerebral and coronary vasodilator, with no bitter taste |
| FR2193587A1 (en) * | 1972-07-31 | 1974-02-22 | Centre Etd Ind Pharma | Vincamine lauryl sulphate compsns - for humans and animals, as a cerebral and coronary vasodilator, without bitter taste |
| ES430063A1 (es) * | 1974-09-14 | 1976-10-01 | Corbera Gubern | Procedimiento para la obtencion de una sal del acido alfa- cetoglutarico. |
| JPS5840529B2 (ja) * | 1975-09-29 | 1983-09-06 | 明治製菓株式会社 | ケイコウヨウセイザイノセイホウ |
| GB1549501A (en) * | 1976-06-03 | 1979-08-08 | Mora E | Adducts of vincamine and apovincamine |
-
1981
- 1981-07-16 US US06/283,706 patent/US4362730A/en not_active Expired - Fee Related
- 1981-07-17 AT AT81105633T patent/ATE7698T1/de active
- 1981-07-17 DE DE8181105633T patent/DE3163875D1/de not_active Expired
- 1981-07-17 EP EP81105633A patent/EP0046506B1/de not_active Expired
- 1981-08-19 GR GR65818A patent/GR75738B/el unknown
- 1981-08-20 YU YU2016/81A patent/YU42246B/xx unknown
- 1981-08-24 KR KR1019810003087A patent/KR840000702B1/ko active
- 1981-08-24 DK DK373181A patent/DK151806C/da not_active IP Right Cessation
- 1981-08-24 HU HU812452A patent/HU187626B/hu not_active IP Right Cessation
- 1981-08-24 IE IE1933/81A patent/IE51568B1/en unknown
- 1981-08-24 FI FI812602A patent/FI71319C/fi not_active IP Right Cessation
- 1981-08-24 JP JP56132555A patent/JPS5775982A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| FI812602L (fi) | 1982-02-26 |
| IE51568B1 (en) | 1987-01-21 |
| JPS6230994B2 (da) | 1987-07-06 |
| GR75738B (da) | 1984-08-02 |
| US4362730A (en) | 1982-12-07 |
| EP0046506A1 (de) | 1982-03-03 |
| EP0046506B1 (de) | 1984-05-30 |
| KR840000702B1 (ko) | 1984-05-21 |
| IE811933L (en) | 1982-02-25 |
| HU187626B (en) | 1986-02-28 |
| YU42246B (en) | 1988-06-30 |
| ATE7698T1 (de) | 1984-06-15 |
| DK151806C (da) | 1988-06-06 |
| YU201681A (en) | 1984-02-29 |
| FI71319C (fi) | 1986-12-19 |
| DE3163875D1 (en) | 1984-07-05 |
| FI71319B (fi) | 1986-09-09 |
| KR830006286A (ko) | 1983-09-20 |
| JPS5775982A (en) | 1982-05-12 |
| DK151806B (da) | 1988-01-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |