DK369588A - 1-substituerede 7-diazabicycloalkyl-6-fluor-4-oxo-1,4-dihydroquinolin-3-carboxylsyre-forbindelser og antibakterielle farmaceutiske praeparater indeholdende disse samt mellemprodukter ved deres fremstilling - Google Patents

1-substituerede 7-diazabicycloalkyl-6-fluor-4-oxo-1,4-dihydroquinolin-3-carboxylsyre-forbindelser og antibakterielle farmaceutiske praeparater indeholdende disse samt mellemprodukter ved deres fremstilling

Info

Publication number
DK369588A
DK369588A DK369588A DK369588A DK369588A DK 369588 A DK369588 A DK 369588A DK 369588 A DK369588 A DK 369588A DK 369588 A DK369588 A DK 369588A DK 369588 A DK369588 A DK 369588A
Authority
DK
Denmark
Prior art keywords
drugs
diazabicycloalkyl
dihydroquinoline
fluor
oxo
Prior art date
Application number
DK369588A
Other languages
Danish (da)
English (en)
Other versions
DK369588D0 (da
Inventor
Edward Fox Kleinman
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DK369588D0 publication Critical patent/DK369588D0/da
Publication of DK369588A publication Critical patent/DK369588A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK369588A 1987-07-02 1988-07-01 1-substituerede 7-diazabicycloalkyl-6-fluor-4-oxo-1,4-dihydroquinolin-3-carboxylsyre-forbindelser og antibakterielle farmaceutiske praeparater indeholdende disse samt mellemprodukter ved deres fremstilling DK369588A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1987/001583 WO1989000158A1 (en) 1987-07-02 1987-07-02 Bridged-diazabicycloalkyl quinolone carboxylic acids and esters

Publications (2)

Publication Number Publication Date
DK369588D0 DK369588D0 (da) 1988-07-01
DK369588A true DK369588A (da) 1989-01-03

Family

ID=22202448

Family Applications (1)

Application Number Title Priority Date Filing Date
DK369588A DK369588A (da) 1987-07-02 1988-07-01 1-substituerede 7-diazabicycloalkyl-6-fluor-4-oxo-1,4-dihydroquinolin-3-carboxylsyre-forbindelser og antibakterielle farmaceutiske praeparater indeholdende disse samt mellemprodukter ved deres fremstilling

Country Status (6)

Country Link
EP (1) EP0297858A3 (ja)
JP (1) JPH0686450B2 (ja)
DK (1) DK369588A (ja)
FI (1) FI890983A (ja)
PT (1) PT87884A (ja)
WO (1) WO1989000158A1 (ja)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1336090C (en) * 1988-08-31 1995-06-27 Isao Hayakawa Spiro-substituted cyclic amines of quinolone derivatives
US5286723A (en) * 1988-08-31 1994-02-15 Daiichi Seiyaku Co., Ltd. Spiro compound
US7214686B2 (en) 1997-06-30 2007-05-08 Targacept, Inc. Pharmaceutical compositions and methods for effecting dopamine release
EP1519939B9 (en) 2002-07-05 2011-04-06 Targacept, Inc. N-aryl diazaspirocyclic compounds and methods of preparation and use thereof
AU2003254016A1 (en) 2002-07-19 2004-02-09 Catholic Healthcare West Methods and compositions relating to chimeric nicotinic receptor subunits
US7098331B2 (en) 2003-03-05 2006-08-29 Targacept, Inc. Arylvinylazacycloalkane compounds and methods of preparation and use thereof
OA13050A (en) 2003-04-29 2006-11-10 Pfizer Ltd 5,7-diaminopyrazolo [4,3-D] pyrimidines useful in the treatment of hypertension.
PL1678172T3 (pl) 2003-10-15 2010-05-31 Targacept Inc Związki azabicykliczne do łagodzenia bólu oraz leczenia zaburzeń centralnego układu nerwowego
US7572799B2 (en) 2003-11-24 2009-08-11 Pfizer Inc Pyrazolo[4,3-d]pyrimidines as Phosphodiesterase Inhibitors
DE602005011784D1 (de) 2004-04-07 2009-01-29 Pfizer Pyrazoloä4,3-düpyrimidine
EP1802601A1 (en) 2004-09-20 2007-07-04 Targacept, Inc. Azaspiroalkene and azapiroalkane compounds with nicotinic cholinergic receptor activity
US7459469B2 (en) 2004-11-10 2008-12-02 Targacept, Inc. Hydroxybenzoate salts of metanicotine compounds
UA88792C2 (ru) 2004-11-10 2009-11-25 Таргасепт, Інк. Гидроксибензоатные соли метаникотиновых соединений
ATE482959T1 (de) 2005-08-22 2010-10-15 Targacept Inc Heteroarylsubstituierte diazatricycloalkane, verfahren zu deren herstellung und deren anwendung
EP2357174A1 (en) 2006-05-09 2011-08-17 AstraZeneca AB Salt forms of (2S)-(4E)-N-Methyl-5-[(5-Isopropoxy)pyridin-3-yl]-4-penten-2-amine
TWI389889B (zh) 2006-05-09 2013-03-21 Targacept Inc （２ｓ）-（４ｅ）-ｎ-甲基-５-〔３-（５-異丙氧基吡啶）基〕-４-戊烯-２-胺之新穎多晶型
CN104193741B (zh) 2007-10-01 2016-08-24 阿尔法梅根有限责任公司 作为α7-烟碱乙酰胆碱受体配体的奎宁环-4-基甲基1H-吲哚-3-甲酸酯衍生物
CN102648202A (zh) 2009-12-07 2012-08-22 塔加西普特公司 作为神经元烟碱乙酰胆碱受体配体的3,6-二氮杂双环[3.1.1]庚烷
SG185497A1 (en) 2010-05-20 2012-12-28 Astrazeneca Ab New process for the preparation of aryl substituted olefinic amines
WO2016007630A1 (en) 2014-07-11 2016-01-14 Alpharmagen, Llc Quinuclidine compounds for modulating alpha7 -nicotinic acetylcholine receptor activity

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3947445A (en) * 1974-05-09 1976-03-30 Stanford Research Institute Diazabicyclooctanes and diazabicycloheptanes
US3954766A (en) * 1975-07-09 1976-05-04 Stanford Research Institute 1,4-Diazabicyclo[3.2.1]octanes
LU77362A1 (ja) * 1977-05-17 1979-01-19
DE2726571A1 (de) * 1977-06-13 1978-12-21 Basf Ag Neue bispidinderivate, verfahren zu deren herstellung und arzneimittel, welche diese enthalten
US4665079A (en) * 1984-02-17 1987-05-12 Warner-Lambert Company Antibacterial agents
DE3234697A1 (de) * 1982-09-18 1984-03-22 Kali-Chemie Pharma Gmbh, 3000 Hannover Neue diazabicyclo-(3,3,1)-nonane
US4571396A (en) * 1984-04-16 1986-02-18 Warner-Lambert Company Antibacterial agents
US4578473A (en) * 1985-04-15 1986-03-25 Warner-Lambert Company Process for quinoline-3-carboxylic acid antibacterial agents
IN166416B (ja) * 1985-09-18 1990-05-05 Pfizer
DE3601567A1 (de) * 1986-01-21 1987-07-23 Bayer Ag 7-(azabicycloalkyl)-chinoloncarbonsaeure- und -naphthyridon-carbonsaeure-derivate

Also Published As

Publication number Publication date
DK369588D0 (da) 1988-07-01
EP0297858A2 (en) 1989-01-04
JPH0686450B2 (ja) 1994-11-02
WO1989000158A1 (en) 1989-01-12
JPS6416783A (en) 1989-01-20
PT87884A (pt) 1989-06-30
EP0297858A3 (en) 1990-05-30
FI890983A0 (fi) 1989-03-01
FI890983A (fi) 1989-03-01

Similar Documents

Publication Publication Date Title
DK369588A (da) 1-substituerede 7-diazabicycloalkyl-6-fluor-4-oxo-1,4-dihydroquinolin-3-carboxylsyre-forbindelser og antibakterielle farmaceutiske praeparater indeholdende disse samt mellemprodukter ved deres fremstilling
DK359986A (da) Phenylethere, fremgangsmaader til fremstilling samt farmaceutiske midler indeholdende disse
DK25992A (da) Quinolinderivater, deres fremstilling samt farmaeutisk praeparat indeholdende saadanne derivater
DK290986A (da) 2-arylimidazolforbindelser, laegemidler indeholdende disse forbindelser og deres fremstilling
DK231687A (da) Heterocykliske forbindelser, deres fremstilling og anvendelse, samt laegemidler indeholdende disse forbindelser
DK518687A (da) Imidazo-benzoxazinoner, deres fremstilling og laegemidler indholdende forbindelserne
NO308287B1 (no) Substituerte 4-fenyl-6-amino-nikotinsyrederivater, legemidler inneholdende disse samt deres anvendelse
DK164594C (da) 1,4-dihydro-pyridin-3,5-yl-dicarboxylsyrederivater, farmaceutiske praeparater indeholdende disse derivater samt fremgangsmaade til fremstilling deraf
DK160986C (da) Ferrikomplekser, deres anvendelse samt farmaceutiske praeparater indeholdende disse
DK161383C (da) Quinolincarboxylsyre-derivat, fremgangsmaade til fremstilling heraf samt antibakterielle farmaceutiske praeparater indeholdende dette
DK166279C (da) 3,4-dihydro-2h-benzooebaapyranderivater, deres fremstilling og laegemidler indeholdende disse forbindelser
DK642588A (da) Indanderivater, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende samme
DK592189A (da) Nitroimidazoler, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende samme
DK66086A (da) Dihydropyridiner, fremgangsmaader til fremstilling heraf samt farmaceutiske midler indeholdende disse
DK170788D0 (da) Dihydropyridazinonderivater, fremgangsmaader til fremstilling heraf samt laegemidler indeholdende disse
NO880474D0 (no) Alkylsubstituerte n-benzopyranyllaktaner, fremgangsmaate til deres fremstilling, deres anvendelse samt farmasoeytiske preparater paa basis av disse forbindelser.
DK384088A (da) Substituerede benzimidazoler, deres fremstilling, praeparater indeholdende disse samt deres anvendelse som laegemidler
DK143188D0 (da) Farmaceutiske praeparater indeholdende pyranoquinolinforbindelser samt deres anvendelse
DK469189A (da) Substituerede thienopyraner, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende samme
DK307085A (da) 4-phenyl-2-trifluormethyl-1,3-dioxan-5-ylheptensyrederivater, fremgangsmaade til fremstilling deraf samt farmaceutiske midler indeholdende disse
DK162984C (da) 1-(2-ar-2-halogen-2-ethenyl)-1h-azoler, fremgangsmaade til deres fremstilling samt farmaceutiske praeparater indeholdende disse
NO863461L (no) 3-desmetyl-mevalonsyrederivater, fremgangsmaate til deres fremstilling, farmasoeytiske preparater paa basis av disse forbindelser, deres anvendelse, samt mellomprodukter.
DK449989A (da) Quinolinderivater, deres fremstilling og laegemidler indeholdende disse derivater
NO883609L (no) Farmasoeytiske preparater for topisk anvendelse.
DK610388A (da) (6-(hetero) aryloxy-naphthalin-2-yl-oxy)-alkancarboxylsyrederivater, deres fremstilling og anvendelse samt ved fremgangsmaaden anvendelige mellemprodukter og disses fremstilling

Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment