DK3671200T3 - Ce-western-applikationer til udvikling af antistof - Google Patents

Ce-western-applikationer til udvikling af antistof Download PDF

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Publication number
DK3671200T3
DK3671200T3 DK19218272.3T DK19218272T DK3671200T3 DK 3671200 T3 DK3671200 T3 DK 3671200T3 DK 19218272 T DK19218272 T DK 19218272T DK 3671200 T3 DK3671200 T3 DK 3671200T3
Authority
DK
Denmark
Prior art keywords
western
applications
antibody development
antibody
development
Prior art date
Application number
DK19218272.3T
Other languages
Danish (da)
English (en)
Inventor
Nisha Palackal
Kun Lu
Gangadhar Dhulipala
Erica Pyles
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Application granted granted Critical
Publication of DK3671200T3 publication Critical patent/DK3671200T3/da

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44704Details; Accessories
    • G01N27/44717Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721Arrangements for investigating the separated zones, e.g. localising zones by optical means
    • G01N27/44726Arrangements for investigating the separated zones, e.g. localising zones by optical means using specific dyes, markers or binding molecules
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44704Details; Accessories
    • G01N27/44717Arrangements for investigating the separated zones, e.g. localising zones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44704Details; Accessories
    • G01N27/44743Introducing samples
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306Solid-phase reaction mechanisms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44756Apparatus specially adapted therefor
    • G01N27/44795Isoelectric focusing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK19218272.3T 2018-12-19 2019-12-19 Ce-western-applikationer til udvikling af antistof DK3671200T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201862781790P 2018-12-19 2018-12-19

Publications (1)

Publication Number Publication Date
DK3671200T3 true DK3671200T3 (da) 2023-08-21

Family

ID=69410996

Family Applications (1)

Application Number Title Priority Date Filing Date
DK19218272.3T DK3671200T3 (da) 2018-12-19 2019-12-19 Ce-western-applikationer til udvikling af antistof

Country Status (9)

Country Link
US (2) US11782023B2 (enExample)
EP (2) EP3671200B1 (enExample)
JP (1) JP2020101545A (enExample)
CA (1) CA3065460A1 (enExample)
DK (1) DK3671200T3 (enExample)
ES (1) ES2955171T3 (enExample)
FI (1) FI3671200T3 (enExample)
HU (1) HUE062818T2 (enExample)
PL (1) PL3671200T3 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3140713A1 (en) * 2019-05-21 2020-11-26 Regeneron Pharmaceuticals, Inc. Methods for identifying and quantitating host cell protein
EP4493921A1 (en) * 2022-03-18 2025-01-22 Regeneron Pharmaceuticals, Inc. Methods and systems for analyzing polypeptide variants

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5002582A (en) 1982-09-29 1991-03-26 Bio-Metric Systems, Inc. Preparation of polymeric surfaces via covalently attaching polymers
US6087188A (en) 1992-11-13 2000-07-11 Alk A/S Two-site immunoassay for an antibody with chemiluminescent label and biotin bound ligand
ATE215696T1 (de) 1993-12-23 2002-04-15 Tropix Inc Chemilumineszenz-assay mittels energietransfer
DE69605712T2 (de) 1995-03-31 2000-04-27 Laboratory Of Molecular Biophotonics, Hamakita Anwendung von isoelektrischen Punkt Markern bei der isoelektrischen Fokussierung mit Fluoreszenzdetektierung
US6165800A (en) 1997-05-30 2000-12-26 Bayer Corporation Chemiluminescent energy transfer conjugates and their uses as labels in binding assays
US6126870A (en) 1997-09-12 2000-10-03 Lumigen, Inc. Chemiluminescent labeling compounds
US6254634B1 (en) 1998-06-10 2001-07-03 Surmodics, Inc. Coating compositions
CA2306752C (en) 1998-08-14 2008-11-18 Dainichiseika Color & Chemicals Mfg. Co., Ltd. Chemiluminescent reagent and chemiluminescent analysis using the same
US6613513B1 (en) 1999-02-23 2003-09-02 Caliper Technologies Corp. Sequencing by incorporation
JP2001249079A (ja) 1999-12-28 2001-09-14 Fujirebio Inc 発光量調節剤を用いた化学発光測定方法及び酵素免疫測定方法
WO2006014680A1 (en) * 2004-07-19 2006-02-09 Cell Biosciences, Inc. Methods and devices for analyte detection
WO2007035864A2 (en) 2005-09-20 2007-03-29 Cell Biosciences, Inc. Electrophoresis standards, methods and kits
US20090023156A1 (en) * 2007-07-20 2009-01-22 Voss Karl O Methods and reagents for quantifying analytes
RU2522002C2 (ru) * 2009-06-26 2014-07-10 Ридженерон Фармасьютикалз, Инк. Легковыделяемые биспецифические антитела с природным иммуноглобулиновым форматом
US9766206B2 (en) * 2013-09-27 2017-09-19 ProteinSimple Apparatus, systems, and methods for capillary electrophoresis
JP7240812B2 (ja) * 2015-05-12 2023-03-16 リジェネロン・ファーマシューティカルズ・インコーポレイテッド 多量体タンパク質の純度の決定

Also Published As

Publication number Publication date
ES2955171T3 (es) 2023-11-29
FI3671200T3 (fi) 2023-08-28
JP2020101545A (ja) 2020-07-02
US20200200707A1 (en) 2020-06-25
PL3671200T3 (pl) 2023-10-09
EP3671200B1 (en) 2023-06-21
EP4253950A3 (en) 2024-01-17
US20230417701A1 (en) 2023-12-28
EP4253950A2 (en) 2023-10-04
US11782023B2 (en) 2023-10-10
CA3065460A1 (en) 2020-06-19
EP3671200A1 (en) 2020-06-24
HUE062818T2 (hu) 2023-12-28

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