DK361376A - PROCEDURE FOR THE PREPARATION OF ANTI-INFLAMMATORY 4,5-DIARYL-2- (SUBST.THIO) IMIDAZOLES - Google Patents

PROCEDURE FOR THE PREPARATION OF ANTI-INFLAMMATORY 4,5-DIARYL-2- (SUBST.THIO) IMIDAZOLES

Info

Publication number
DK361376A
DK361376A DK361376A DK361376A DK361376A DK 361376 A DK361376 A DK 361376A DK 361376 A DK361376 A DK 361376A DK 361376 A DK361376 A DK 361376A DK 361376 A DK361376 A DK 361376A
Authority
DK
Denmark
Prior art keywords
subst
diaryl
imidazoles
thio
inflammatory
Prior art date
Application number
DK361376A
Other languages
Danish (da)
Inventor
S C Cherkofsky
T R Sharpe
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of DK361376A publication Critical patent/DK361376A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK361376A 1975-08-11 1976-08-10 PROCEDURE FOR THE PREPARATION OF ANTI-INFLAMMATORY 4,5-DIARYL-2- (SUBST.THIO) IMIDAZOLES DK361376A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60365075A 1975-08-11 1975-08-11
US69128276A 1976-06-09 1976-06-09

Publications (1)

Publication Number Publication Date
DK361376A true DK361376A (en) 1977-02-12

Family

ID=27084480

Family Applications (1)

Application Number Title Priority Date Filing Date
DK361376A DK361376A (en) 1975-08-11 1976-08-10 PROCEDURE FOR THE PREPARATION OF ANTI-INFLAMMATORY 4,5-DIARYL-2- (SUBST.THIO) IMIDAZOLES

Country Status (26)

Country Link
JP (1) JPS6011702B2 (en)
AR (2) AR215591A1 (en)
AU (1) AU508605B2 (en)
CA (1) CA1074327A (en)
CH (1) CH638791A5 (en)
DD (1) DD126244A5 (en)
DE (1) DE2635876A1 (en)
DK (1) DK361376A (en)
ES (2) ES450601A1 (en)
FI (1) FI66177C (en)
FR (1) FR2320745A1 (en)
GB (1) GB1516908A (en)
GR (1) GR61145B (en)
HU (1) HU174707B (en)
IE (1) IE44019B1 (en)
IL (1) IL50230A (en)
LU (1) LU75578A1 (en)
MX (1) MX3932E (en)
NL (1) NL7608915A (en)
NO (1) NO146571C (en)
NZ (1) NZ181731A (en)
PH (1) PH11857A (en)
PT (1) PT65464B (en)
SE (1) SE428686B (en)
SU (1) SU640662A3 (en)
YU (1) YU198176A (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK16778A (en) * 1977-02-09 1978-08-10 Du Pont IMIDAZOLE DERIVATIVES THEIR USES AND MANUFACTURE
LU77703A1 (en) * 1977-07-07 1979-03-26 Ciba Geigy Ag METHOD FOR PRODUCING BICYCLIC THIA-DIAZA COMPOUNDS
CY1302A (en) * 1978-04-11 1985-12-06 Ciba Geigy Ag Mercapto-imidazole derivatives,their preparation,their pharmaceutical compositions and applications
DE2823197A1 (en) 1978-05-24 1979-11-29 Schering Ag NEW IMIDAZOLE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM
US4308277A (en) * 1978-08-10 1981-12-29 Ciba-Geigy Corporation 2,4,5-Trisubstituted imidazolines and pharmaceutical compositions containing same
US4188397A (en) * 1978-09-22 1980-02-12 Smithkline Corporation 2,2-Alkyldiylbis(thio)bis(imidazoles)
US4215135A (en) * 1979-06-08 1980-07-29 E. I. Du Pont De Nemours And Company Antiinflammatory 2-substituted-1H-phenanthro[9,10-d]imidazoles
DE2856909A1 (en) * 1978-12-28 1980-07-17 Schering Ag NEW IMIDAZOLE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM
GB8907656D0 (en) * 1989-04-05 1989-05-17 May & Baker Ltd New compositions of matter
JP2002515915A (en) * 1997-06-30 2002-05-28 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド 2-Substituted imidazoles useful in treating inflammatory diseases
DE10222103A1 (en) * 2002-05-17 2003-11-27 Merckle Gmbh Chem Pharm Fabrik New 2-(substituted thio)-imidazole derivatives are immunomodulators and cytokine release inhibitors, useful for treating diseases associated with immune system disorders, e.g. cancer or rheumatoid arthritis

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE688585A (en) * 1965-10-21 1967-04-20
US3651080A (en) * 1969-11-07 1972-03-21 Ciba Geigy Corp Certain substituted 2-alkylmercaptoimidazole derivatives
US3636003A (en) * 1969-11-17 1972-01-18 Geigy Chem Corp Substituted 2-mercaptoimidazole derivatives
US3714179A (en) * 1970-09-08 1973-01-30 Searle & Co 1-alkyl-2-furfurylthioimidazoles and congeners
US3707475A (en) * 1970-11-16 1972-12-26 Pfizer Antiinflammatory imidazoles

Also Published As

Publication number Publication date
GB1516908A (en) 1978-07-05
NO762754L (en) 1977-02-14
NO146571B (en) 1982-07-19
HU174707B (en) 1980-03-28
DD126244A5 (en) 1977-07-06
FR2320745A1 (en) 1977-03-11
MX3932E (en) 1981-10-02
NL7608915A (en) 1977-02-15
ES450601A1 (en) 1978-01-16
CH638791A5 (en) 1983-10-14
IL50230A0 (en) 1976-10-31
JPS6011702B2 (en) 1985-03-27
FI66177B (en) 1984-05-31
IE44019B1 (en) 1981-07-29
YU198176A (en) 1982-10-31
ES461193A1 (en) 1978-12-01
SE7607615L (en) 1977-02-12
IE44019L (en) 1977-02-11
PH11857A (en) 1978-08-03
FR2320745B1 (en) 1978-12-22
NZ181731A (en) 1978-11-13
JPS5223076A (en) 1977-02-21
IL50230A (en) 1979-07-25
FI762290A (en) 1977-02-12
LU75578A1 (en) 1978-04-13
AR215591A1 (en) 1979-10-31
AU1671176A (en) 1978-02-16
PT65464B (en) 1978-08-02
CA1074327A (en) 1980-03-25
GR61145B (en) 1978-09-27
SE428686B (en) 1983-07-18
PT65464A (en) 1976-09-01
AR218054A1 (en) 1980-05-15
NO146571C (en) 1982-10-27
FI66177C (en) 1984-09-10
DE2635876A1 (en) 1977-03-03
AU508605B2 (en) 1980-03-27
SU640662A3 (en) 1978-12-30

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment