DK3600315T3 - Ny terapeutisk anvendelse af H3-ligander - Google Patents

Ny terapeutisk anvendelse af H3-ligander Download PDF

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Publication number
DK3600315T3
DK3600315T3 DK18714194.0T DK18714194T DK3600315T3 DK 3600315 T3 DK3600315 T3 DK 3600315T3 DK 18714194 T DK18714194 T DK 18714194T DK 3600315 T3 DK3600315 T3 DK 3600315T3
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DK
Denmark
Prior art keywords
ligands
therapeutic use
new therapeutic
new
therapeutic
Prior art date
Application number
DK18714194.0T
Other languages
English (en)
Inventor
Jeanne-Marie Lecomte
Jean-Charles Schwartz
Olivier Labeeuw
Marc Capet
Original Assignee
Bioprojet Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioprojet Pharma filed Critical Bioprojet Pharma
Application granted granted Critical
Publication of DK3600315T3 publication Critical patent/DK3600315T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK18714194.0T 2017-03-21 2018-03-21 Ny terapeutisk anvendelse af H3-ligander DK3600315T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17305309.1A EP3378477A1 (en) 2017-03-21 2017-03-21 New therapeutical use of h3-ligands
PCT/EP2018/057215 WO2018172432A1 (en) 2017-03-21 2018-03-21 New therapeutical use of h3-ligands

Publications (1)

Publication Number Publication Date
DK3600315T3 true DK3600315T3 (da) 2023-12-11

Family

ID=58464477

Family Applications (1)

Application Number Title Priority Date Filing Date
DK18714194.0T DK3600315T3 (da) 2017-03-21 2018-03-21 Ny terapeutisk anvendelse af H3-ligander

Country Status (24)

Country Link
US (1) US11179329B2 (da)
EP (2) EP3378477A1 (da)
JP (2) JP2020511551A (da)
KR (1) KR20190125354A (da)
CN (1) CN110891570A (da)
AU (1) AU2018238411B2 (da)
BR (1) BR112019019633A2 (da)
CA (1) CA3056710A1 (da)
DK (1) DK3600315T3 (da)
ES (1) ES2971063T3 (da)
FI (1) FI3600315T3 (da)
HR (1) HRP20231568T1 (da)
HU (1) HUE064403T2 (da)
IL (1) IL269424B2 (da)
LT (1) LT3600315T (da)
MA (1) MA48983A (da)
MX (1) MX2019011183A (da)
PL (1) PL3600315T3 (da)
PT (1) PT3600315T (da)
RS (1) RS64910B1 (da)
RU (1) RU2757996C2 (da)
SI (1) SI3600315T1 (da)
WO (1) WO2018172432A1 (da)
ZA (1) ZA201906238B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3378858A1 (en) * 2017-03-21 2018-09-26 Bioprojet Tetrahydrate of h3 ligand, its process of preparation and pharmaceutical compositions comprising the same
ES2840253T3 (es) 2018-07-27 2021-07-06 Bioprojet Soc Civ Combinaciones novedosas de un antagonista de H3 y un inhibidor de la recaptación de noradrenalina y usos terapéuticos de los mismos
WO2020092604A1 (en) * 2018-10-30 2020-05-07 Concert Pharmaceuticals, Inc. Deuterated pitolisant

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2579596B1 (fr) * 1985-03-26 1987-11-20 Inst Nat Sante Rech Med (imidazolyl-4) piperidines, leur preparation et leur application en therapeutique
FR2660862B1 (fr) * 1990-04-13 1994-09-23 Bioprojet Soc Civ Application therapeutique de derives de l'histamine, nouveau derive de l'histamine et utilisation de ces derives pour la preparation de medicaments.
EP0982300A3 (en) * 1998-07-29 2000-03-08 Societe Civile Bioprojet Non-imidazole alkylamines as histamine H3 - receptor ligands and their therapeutic applications
EP1717235A3 (en) 2005-04-29 2007-02-28 Bioprojet Phenoxypropylpiperidines and -pyrrolidines and their use as histamine H3-receptor ligands
ES2384414T3 (es) * 2007-09-06 2012-07-04 Glaxo Group Limited Derivado de piperazina que tiene afinidad por el receptor H3 de histamina
SG188212A1 (en) * 2010-09-02 2013-04-30 Suven Life Sciences Ltd Heterocyclyl compounds as histamine h3 receptor ligands
US9212180B2 (en) * 2013-06-12 2015-12-15 The Regents Of The University Of Michigan Menin-MLL inhibitors and methods of use thereof
EP3378858A1 (en) * 2017-03-21 2018-09-26 Bioprojet Tetrahydrate of h3 ligand, its process of preparation and pharmaceutical compositions comprising the same

Also Published As

Publication number Publication date
WO2018172432A1 (en) 2018-09-27
RU2019129447A3 (da) 2021-03-18
HUE064403T2 (hu) 2024-03-28
MA48983A (fr) 2021-04-21
MX2019011183A (es) 2020-02-05
CA3056710A1 (en) 2018-09-27
AU2018238411A1 (en) 2019-10-10
AU2018238411B2 (en) 2023-07-06
RS64910B1 (sr) 2023-12-29
RU2757996C2 (ru) 2021-10-25
EP3600315B1 (en) 2023-09-06
LT3600315T (lt) 2023-12-27
US11179329B2 (en) 2021-11-23
HRP20231568T1 (hr) 2024-03-15
JP2020511551A (ja) 2020-04-16
PT3600315T (pt) 2023-12-11
BR112019019633A2 (pt) 2020-04-14
EP3378477A1 (en) 2018-09-26
PL3600315T3 (pl) 2024-03-18
KR20190125354A (ko) 2019-11-06
CN110891570A (zh) 2020-03-17
ES2971063T3 (es) 2024-06-03
ZA201906238B (en) 2020-09-30
IL269424B1 (en) 2023-03-01
FI3600315T3 (fi) 2023-12-11
US20200093738A1 (en) 2020-03-26
RU2019129447A (ru) 2021-03-18
JP2023001210A (ja) 2023-01-04
IL269424B2 (en) 2023-07-01
IL269424A (en) 2019-11-28
SI3600315T1 (sl) 2024-02-29
EP3600315A1 (en) 2020-02-05

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