DK3577A - Fremgangsmade til fremstilling af anestetisk virksomme steroider - Google Patents

Fremgangsmade til fremstilling af anestetisk virksomme steroider

Info

Publication number
DK3577A
DK3577A DK3577A DK3577A DK3577A DK 3577 A DK3577 A DK 3577A DK 3577 A DK3577 A DK 3577A DK 3577 A DK3577 A DK 3577A DK 3577 A DK3577 A DK 3577A
Authority
DK
Denmark
Prior art keywords
procedure
preparation
anesthetically effective
effective steroids
steroids
Prior art date
Application number
DK3577A
Other languages
Danish (da)
English (en)
Inventor
G H Phillipps
P J May
B E Ayres
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of DK3577A publication Critical patent/DK3577A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • A61P23/02Local anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J13/00Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J17/00Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J3/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0088Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing unsubstituted amino radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0007Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
    • C07J5/0015Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa not substituted in position 16
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J63/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008Expansion of ring D by one atom, e.g. D homo steroids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/0015Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
    • C07J7/0025Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa substituted in position 16
    • C07J7/003Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/001Oxiranes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Neurology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK3577A 1976-01-06 1977-01-05 Fremgangsmade til fremstilling af anestetisk virksomme steroider DK3577A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB357/76A GB1570394A (en) 1976-01-06 1976-01-06 11-acyloxy-3-hydroxy steroids

Publications (1)

Publication Number Publication Date
DK3577A true DK3577A (da) 1977-07-07

Family

ID=9702974

Family Applications (1)

Application Number Title Priority Date Filing Date
DK3577A DK3577A (da) 1976-01-06 1977-01-05 Fremgangsmade til fremstilling af anestetisk virksomme steroider

Country Status (12)

Country Link
JP (1) JPS5285159A (en:Method)
AU (1) AU513579B2 (en:Method)
BE (1) BE850108A (en:Method)
CA (1) CA1084903A (en:Method)
DE (1) DE2700267A1 (en:Method)
DK (1) DK3577A (en:Method)
FR (1) FR2361419A1 (en:Method)
GB (1) GB1570394A (en:Method)
NL (1) NL7700054A (en:Method)
NZ (1) NZ183004A (en:Method)
SE (1) SE7700098L (en:Method)
ZA (1) ZA7759B (en:Method)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ300694A3 (en) * 1993-12-02 1996-05-15 Akzo Nobel Nv Substituted 2beta-morpholinandrostane derivatives, process of their preparation, their use for preparing pharmaceutical preparations and pharmaceutical compositions containing thereof
GB0105772D0 (en) * 2001-03-08 2001-04-25 Sterix Ltd Use
ES2738526T3 (es) 2011-10-14 2020-01-23 Sage Therapeutics Inc Compuestos 19-norpregnano 3,3-disustituidos, composiciones y usos de los mismos
NZ773177A (en) 2012-01-23 2022-09-30 Sage Therapeutics Inc Neuroactive steroid formulations and methods of treating cns disorders
IL275725B (en) 2012-08-21 2022-08-01 Sage Therapeutics Inc Treatment methods for epilepsy and status epilepticus
AU2014256229B2 (en) 2013-04-17 2018-10-04 Sage Therapeutics, Inc. 19-nor C3,3-disubstituted C21-N-pyrazolyl steroids and methods of use thereof
RS60420B1 (sr) 2013-04-17 2020-07-31 Sage Therapeutics Inc 19-nor neuroaktivni steroidi za metode lečenja
US9725481B2 (en) 2013-04-17 2017-08-08 Sage Therapeutics, Inc. 19-nor C3, 3-disubstituted C21-C-bound heteroaryl steroids and methods of use thereof
WO2014169836A1 (en) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor neuroactive steroids and methods of use thereof
PL3021852T3 (pl) * 2013-07-19 2021-07-05 Sage Therapeutics, Inc. Neuroaktywne steroidy, kompozycje i ich zastosowania
JP6466942B2 (ja) 2013-08-23 2019-02-06 セージ セラピューティクス, インコーポレイテッド 向神経活性ステロイド、組成物、及びその使用
US10246482B2 (en) 2014-06-18 2019-04-02 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
JOP20200195A1 (ar) 2014-09-08 2017-06-16 Sage Therapeutics Inc سترويدات وتركيبات نشطة عصبياً، واستخداماتها
HUE051488T2 (hu) 2014-10-16 2021-03-01 Sage Therapeutics Inc Készítmények és eljárások központi idegrendszeri rendellenességek kezelésére
WO2016061527A1 (en) 2014-10-16 2016-04-21 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
US10774108B2 (en) 2014-11-27 2020-09-15 Sage Therapeutics, Inc. Compositions and methods for treating CNS disorders
PL3250210T3 (pl) 2015-01-26 2021-07-26 Sage Therapeutics, Inc. Kompozycje i sposoby leczenia zaburzeń OUN
JP6875996B2 (ja) 2015-02-20 2021-05-26 セージ セラピューティクス, インコーポレイテッド 神経刺激性ステロイド、組成物、およびその使用
EP4509079A3 (en) 2015-06-10 2025-04-23 Boston Scientific Scimed, Inc. Bodily substance detection by evaluating photoluminescent response to excitation radiation
WO2017156103A1 (en) 2016-03-08 2017-09-14 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
JP7049313B2 (ja) 2016-07-11 2022-04-06 セージ セラピューティクス, インコーポレイテッド C17、c20、およびc21置換神経刺激性ステロイドおよびそれらの使用方法
ES2992037T3 (es) 2016-07-11 2024-12-05 Sage Therapeutics Inc Esteroides neuroactivos sustituidos en C7, C12 y C16 y sus procedimientos de utilización
AR114044A1 (es) * 2017-12-22 2020-07-15 Sage Therapeutics Inc Composiciones y métodos para el tratamiento de trastornos en el sistema nervioso central
TWI874337B (zh) 2018-12-05 2025-03-01 美商賽吉醫療公司 神經活性類固醇及其使用方法
CR20240234A (es) 2019-05-31 2024-07-09 Sage Therapeutics Inc ESTEROIDES NEUROACTIVOS Y COMPOSICIONES DE ESTOS (Divisional 2021-629)
KR20220038681A (ko) * 2019-06-27 2022-03-29 세이지 테라퓨틱스, 인크. Cns 장애를 치료하기 위한 조성물 및 방법
CA3143545A1 (en) * 2019-06-27 2020-12-30 Sage Therapeutics, Inc. Compounds for treating cns disorders

Also Published As

Publication number Publication date
BE850108A (fr) 1977-07-05
DE2700267A1 (de) 1977-07-14
AU2106577A (en) 1978-07-13
CA1084903A (en) 1980-09-02
FR2361419A1 (fr) 1978-03-10
SE7700098L (sv) 1977-07-07
FR2361419B1 (en:Method) 1980-04-04
AU513579B2 (en) 1980-12-11
JPS5285159A (en) 1977-07-15
ZA7759B (en) 1978-02-22
GB1570394A (en) 1980-07-02
NL7700054A (nl) 1977-07-08
NZ183004A (en) 1980-03-05

Similar Documents

Publication Publication Date Title
DK148677A (da) Fremgangsmade til fremstilling af anestetisk virksomme steroider
DK3577A (da) Fremgangsmade til fremstilling af anestetisk virksomme steroider
DK30277A (da) Fremgangsmade til fremstilling af substituerede phenylamidiner
DK377A (da) Fremgangsmade til fremstilling af n-phosphonomethyl-glycin
DK244577A (da) Fremgangsmade til fremstilling af hydantoinderivater
DK276177A (da) Fremgangsmade til fremstilling af gammapyron-forbindelser
DK577977A (da) Fremgangsmaade til fremstilling af alfa-l-aspartyl-l-phenylalanin-methyler
DK339677A (da) Fremgangsmade til fremstilling af 2-benzylpyrrolidiner
DK587077A (da) Fremgangsmaade til fremstilling af estere
DK144377A (da) Fremgangsmade til fremstilling af acylcyanider
DK233477A (da) Fremgangsmade til fremstilling af antiotiske midler
DK88777A (da) Fremgangsmade til fremstilling af substituerede azapuriner
DK271377A (da) Fremgangsmade til fremstilling af substituerede arylacetamidocephalosporiner
DK216977A (da) Fremgangsmade til fremstilling af imidazobenzoxaziner
DK144277A (da) Fremgangsmade til fremstilling af acylcyanider
DK575077A (da) Fremgangsmaade til fremstilling af 0-alkylerede oximer
DK195077A (da) Fremgangsmade til fremstilling af benzodiazepiner
DK73277A (da) Fremgangsmaade til fremstilling af sulfonylbenzimidazoler
DK575277A (da) Fremgangsmaade til fremstilling af basisk substituerede 0-propyloximer
DK438277A (da) Fremgangsmaade til fremstilling af 9-chlorprednisoloner
DK196577A (da) Fremgangsmade til fremstilling af kolecystokinin-pankreozymin-oktapeptidamidsulfatester
DK538977A (da) Fremgangsmaade til fremstilling af 17alfa-hydroxy-21-acetoxy-progesteron
DK582177A (da) Fremgangsmaade til fremstilling af halogenacylamider
DK564977A (da) Fremgangsmaade til fremstilling af antirhinovirusmidler
DK338677A (da) Frefmgangsmade til fremstilling af 3-alkoxycyproheptadiner

Legal Events

Date Code Title Description
ATS Application withdrawn