DK3520797T3 - Carboxylerede derivater af glycosaminoglycaner og anvendelse som lægemidler - Google Patents
Carboxylerede derivater af glycosaminoglycaner og anvendelse som lægemidler Download PDFInfo
- Publication number
- DK3520797T3 DK3520797T3 DK19164954.0T DK19164954T DK3520797T3 DK 3520797 T3 DK3520797 T3 DK 3520797T3 DK 19164954 T DK19164954 T DK 19164954T DK 3520797 T3 DK3520797 T3 DK 3520797T3
- Authority
- DK
- Denmark
- Prior art keywords
- glycosaminoglycans
- drugs
- carboxylated derivatives
- carboxylated
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0069—Chondroitin-4-sulfate, i.e. chondroitin sulfate A; Dermatan sulfate, i.e. chondroitin sulfate B or beta-heparin; Chondroitin-6-sulfate, i.e. chondroitin sulfate C; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
- C08B37/0078—Degradation products
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Polymers & Plastics (AREA)
- Materials Engineering (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000006A ITLO20130006A1 (it) | 2013-11-06 | 2013-11-06 | Derivati carbossilati di glucosamminoglicani e loro uso come farmaci |
| EP17205232.6A EP3308791B1 (en) | 2013-11-06 | 2014-10-22 | Carboxylated derivatives of glycosaminoglycans and use as drugs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3520797T3 true DK3520797T3 (da) | 2020-11-09 |
Family
ID=49683858
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK14790560.8T DK3065747T3 (da) | 2013-11-06 | 2014-10-22 | Carboxylerede derivater af glucosaminoglycaner og anvendelse som lægemidler |
| DK19164954.0T DK3520797T3 (da) | 2013-11-06 | 2014-10-22 | Carboxylerede derivater af glycosaminoglycaner og anvendelse som lægemidler |
| DK17205232.6T DK3308791T3 (da) | 2013-11-06 | 2014-10-22 | Carboxylerede derivater af glycosaminoglycaner og anvendelse som lægemidler |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK14790560.8T DK3065747T3 (da) | 2013-11-06 | 2014-10-22 | Carboxylerede derivater af glucosaminoglycaner og anvendelse som lægemidler |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17205232.6T DK3308791T3 (da) | 2013-11-06 | 2014-10-22 | Carboxylerede derivater af glycosaminoglycaner og anvendelse som lægemidler |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US10822430B2 (da) |
| EP (3) | EP3065747B1 (da) |
| JP (1) | JP6784454B2 (da) |
| KR (1) | KR102113905B1 (da) |
| CN (2) | CN110218268B (da) |
| CY (2) | CY1120221T1 (da) |
| DK (3) | DK3065747T3 (da) |
| ES (3) | ES2724475T3 (da) |
| HK (1) | HK1222797A1 (da) |
| IT (1) | ITLO20130006A1 (da) |
| PL (3) | PL3520797T3 (da) |
| PT (3) | PT3308791T (da) |
| TR (2) | TR201906180T4 (da) |
| WO (1) | WO2015067471A1 (da) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111670038B (zh) * | 2018-02-02 | 2024-01-26 | 深圳市海普瑞药业集团股份有限公司 | 糖胺聚糖衍生物及其制备方法和用途 |
| CN114689722A (zh) * | 2020-12-31 | 2022-07-01 | 深圳市海普瑞药业集团股份有限公司 | 一种用于检测样品中糖胺聚糖羧酸化衍生物含量的方法及其应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA928218A (en) * | 1969-06-17 | 1973-06-12 | Recherche Et Industrie Therapeutiques R.I.T. | Antiinfectious compositions and process for their preparation |
| GB1295666A (da) * | 1969-06-17 | 1972-11-08 | ||
| IT1230582B (it) | 1988-10-21 | 1991-10-28 | Opocrin S P A Lab Farmabiologi | Oliogosaccaridi di dermatan solfato ed eparina aventi attivita' antiaterosclerotica |
| SE466779B (sv) | 1991-02-13 | 1992-03-30 | L T S I Soederkoeping Ab | Anordning vid ett kylsystem foer kylning av teleteknisk utrustning |
| US5250519A (en) | 1991-03-29 | 1993-10-05 | Glycomed Incorporated | Non-anticoagulant heparin derivatives |
| IL131074A0 (en) * | 1999-07-23 | 2001-03-19 | Polygene Ltd | A biodegradable polycation composition for delivery of an anionic macromolecule |
| US7781416B2 (en) | 2000-01-25 | 2010-08-24 | Sigma-Tau Research Switzerland S.A. | Derivatives of partially desulphated glycosaminoglycans as heparanase inhibitors, endowed with antiangiogenic activity and devoid of anticoagulating effect |
| IT1316986B1 (it) * | 2000-01-25 | 2003-05-26 | Sigma Tau Ind Farmaceuti | Derivati glicosamminoglicani parzialmente desolfatati nonanticoagulanti ad attivita' antiangiogenica. |
| US20020062019A1 (en) * | 2000-03-30 | 2002-05-23 | Pasqua Oreste | Glycosaminoglycans derived from K5 polysaccharide having high anticoagulant and antithrombotic activities and process for their preparation |
| EP1427427B1 (en) * | 2001-09-12 | 2011-06-08 | SIGMA-TAU Research Switzerland S.A. | Derivatives of partially desulphated glycosaminoglycans as heparanase inhibitors, endowed with antiangiogenic activity and devoid of anticoagulating effect |
| JP5572095B2 (ja) * | 2007-11-02 | 2014-08-13 | モメンタ ファーマシューティカルズ インコーポレイテッド | 非抗凝固性多糖組成物 |
-
2013
- 2013-11-06 IT IT000006A patent/ITLO20130006A1/it unknown
-
2014
- 2014-10-22 ES ES17205232T patent/ES2724475T3/es active Active
- 2014-10-22 EP EP14790560.8A patent/EP3065747B1/en active Active
- 2014-10-22 ES ES19164954T patent/ES2835173T3/es active Active
- 2014-10-22 DK DK14790560.8T patent/DK3065747T3/da active
- 2014-10-22 PT PT17205232T patent/PT3308791T/pt unknown
- 2014-10-22 KR KR1020167014561A patent/KR102113905B1/ko active IP Right Grant
- 2014-10-22 CN CN201910539702.XA patent/CN110218268B/zh active Active
- 2014-10-22 ES ES14790560.8T patent/ES2660777T3/es active Active
- 2014-10-22 TR TR2019/06180T patent/TR201906180T4/tr unknown
- 2014-10-22 PL PL19164954T patent/PL3520797T3/pl unknown
- 2014-10-22 PT PT147905608T patent/PT3065747T/pt unknown
- 2014-10-22 PL PL14790560T patent/PL3065747T3/pl unknown
- 2014-10-22 TR TR2018/02314T patent/TR201802314T4/tr unknown
- 2014-10-22 EP EP19164954.0A patent/EP3520797B1/en active Active
- 2014-10-22 JP JP2016550977A patent/JP6784454B2/ja active Active
- 2014-10-22 PL PL17205232T patent/PL3308791T3/pl unknown
- 2014-10-22 CN CN201480063192.9A patent/CN105744940B/zh active Active
- 2014-10-22 EP EP17205232.6A patent/EP3308791B1/en active Active
- 2014-10-22 WO PCT/EP2014/072676 patent/WO2015067471A1/en active Application Filing
- 2014-10-22 PT PT191649540T patent/PT3520797T/pt unknown
- 2014-10-22 DK DK19164954.0T patent/DK3520797T3/da active
- 2014-10-22 DK DK17205232.6T patent/DK3308791T3/da active
- 2014-10-22 US US15/034,555 patent/US10822430B2/en active Active
-
2016
- 2016-09-20 HK HK16111020.3A patent/HK1222797A1/zh unknown
-
2018
- 2018-02-23 CY CY20181100223T patent/CY1120221T1/el unknown
-
2019
- 2019-04-24 CY CY20191100449T patent/CY1121569T1/el unknown
-
2020
- 2020-02-04 US US16/781,735 patent/US11332548B2/en active Active
- 2020-02-21 US US16/798,065 patent/US11370848B2/en active Active
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