DK344783D0 - Fremgangsmade til fremstilling af phenothiazinderivater - Google Patents
Fremgangsmade til fremstilling af phenothiazinderivaterInfo
- Publication number
- DK344783D0 DK344783D0 DK3447/83A DK344783A DK344783D0 DK 344783 D0 DK344783 D0 DK 344783D0 DK 3447/83 A DK3447/83 A DK 3447/83A DK 344783 A DK344783 A DK 344783A DK 344783 D0 DK344783 D0 DK 344783D0
- Authority
- DK
- Denmark
- Prior art keywords
- procedure
- phenothiazine derivatives
- formula
- preparing
- preparing phenothiazine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
- C07D279/18—[b, e]-condensed with two six-membered rings
- C07D279/22—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom
- C07D279/24—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom
- C07D279/26—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom without other substituents attached to the ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
- C07C217/62—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
- C07D279/18—[b, e]-condensed with two six-membered rings
- C07D279/22—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom
- C07D279/24—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom
- C07D279/28—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom with other substituents attached to the ring system
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B21/00—Thiazine dyes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/402,704 US4471116A (en) | 1982-07-28 | 1982-07-28 | Substituted (10H-phenothiazin-10-L)-propyl-1-piperazines |
Publications (2)
Publication Number | Publication Date |
---|---|
DK344783D0 true DK344783D0 (da) | 1983-07-27 |
DK344783A DK344783A (da) | 1984-03-12 |
Family
ID=23592997
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK344783A DK344783A (da) | 1982-07-28 | 1983-07-27 | Fremgangsmaade til fremstilling af phenothiazinderivater |
Country Status (13)
Country | Link |
---|---|
US (1) | US4471116A (da) |
EP (1) | EP0100033B1 (da) |
JP (1) | JPS5942372A (da) |
AT (1) | ATE24902T1 (da) |
AU (1) | AU566225B2 (da) |
CA (1) | CA1209139A (da) |
DE (1) | DE3369133D1 (da) |
DK (1) | DK344783A (da) |
IE (1) | IE55747B1 (da) |
IL (1) | IL69340A (da) |
NZ (1) | NZ205024A (da) |
PH (1) | PH18816A (da) |
ZA (1) | ZA835469B (da) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8628903D0 (en) * | 1986-12-03 | 1987-01-07 | Lunbeck A S H | Neuroleptic compounds |
US5047540A (en) * | 1987-12-17 | 1991-09-10 | Shionogi & Co., Ltd. | Lipid derivatives |
FR2626877B1 (fr) * | 1988-02-05 | 1991-04-05 | Delalande Sa | Ethers alkyliques ou benzyliques du phenol, leurs procedes de preparation et leur application en therapeutique |
SE467330B (sv) * | 1990-10-03 | 1992-06-29 | Ericsson Telefon Ab L M | Saett att linearisera en oeverfoeringsfunktion hos en modulatoranordning samt modulatoranordning med lineariserad oeverfoeringsfunktion |
GB9207855D0 (en) * | 1992-04-09 | 1992-05-27 | Ici Plc | Therapeutic amines |
US7119312B2 (en) * | 2004-07-09 | 2006-10-10 | Sedlmayr Steven R | Microwave fluid heating and distillation method |
US7432482B2 (en) * | 2004-07-09 | 2008-10-07 | Sedlmayr Steven R | Distillation and distillate method by microwaves |
US20090134152A1 (en) * | 2005-10-27 | 2009-05-28 | Sedlmayr Steven R | Microwave nucleon-electron-bonding spin alignment and alteration of materials |
DE102010062810B4 (de) * | 2010-09-07 | 2014-03-13 | Immungenetics Ag | 2-(R2-Thio)-10-[3-(4-R1-piperazin-1-yl)propyl]-10H-phenothiazine zur Behandlung neurodegenerativer Erkrankungen ausgewählt aus beta-Amyloidopathien und alpha-Synucleinopathien |
ES2610206B1 (es) * | 2015-09-23 | 2018-02-07 | Consejo Superior De Investigaciones Científicas (Csic) | Aminofenotiazinas para la modulación del número de sinapsis |
KR102227352B1 (ko) * | 2018-07-24 | 2021-03-12 | 주식회사 프로텍바이오 | 신규한 오토택 키메라 화합물, 이를 포함하는 표적 단백질 분해를 통한 질환의 예방, 개선 또는 치료용 조성물 |
CN109160882B (zh) * | 2018-08-28 | 2021-07-09 | 杭州师范大学 | 一种盐酸左布诺洛尔的制备方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1199227A (fr) * | 1957-05-31 | 1959-12-11 | Rhone Poulenc Sa | Nouveaux dérivés de la phénothiazine à chaîne pipérazinique substituée par un radical carbamoyle et leurs procédés de préparation |
US3081229A (en) * | 1958-12-09 | 1963-03-12 | American Home Prod | Phenothiazines with antihistaminic and antipsychotic activity |
US3264290A (en) * | 1963-02-28 | 1966-08-02 | Squibb & Sons Inc | Basic ethers of hydroxyethylpiperazinopropylphenothiazines |
HU179190B (en) * | 1979-04-06 | 1982-09-28 | Gyogyszerkutato Intezet | Process for preparing new phenthiazine derivatives |
-
1982
- 1982-07-28 US US06/402,704 patent/US4471116A/en not_active Expired - Fee Related
-
1983
- 1983-07-15 DE DE8383106938T patent/DE3369133D1/de not_active Expired
- 1983-07-15 EP EP83106938A patent/EP0100033B1/de not_active Expired
- 1983-07-15 AT AT83106938T patent/ATE24902T1/de not_active IP Right Cessation
- 1983-07-26 CA CA000433256A patent/CA1209139A/en not_active Expired
- 1983-07-26 IL IL69340A patent/IL69340A/xx unknown
- 1983-07-26 ZA ZA835469A patent/ZA835469B/xx unknown
- 1983-07-26 NZ NZ205024A patent/NZ205024A/en unknown
- 1983-07-27 JP JP58135991A patent/JPS5942372A/ja active Pending
- 1983-07-27 PH PH29300A patent/PH18816A/en unknown
- 1983-07-27 DK DK344783A patent/DK344783A/da not_active Application Discontinuation
- 1983-07-27 IE IE1772/83A patent/IE55747B1/xx unknown
- 1983-07-28 AU AU17383/83A patent/AU566225B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
IL69340A0 (en) | 1983-11-30 |
US4471116A (en) | 1984-09-11 |
IE831772L (en) | 1984-01-28 |
JPS5942372A (ja) | 1984-03-08 |
DE3369133D1 (en) | 1987-02-19 |
AU566225B2 (en) | 1987-10-15 |
AU1738383A (en) | 1984-02-02 |
DK344783A (da) | 1984-03-12 |
PH18816A (en) | 1985-10-03 |
EP0100033B1 (de) | 1987-01-14 |
ATE24902T1 (de) | 1987-01-15 |
IE55747B1 (en) | 1991-01-02 |
NZ205024A (en) | 1986-10-08 |
CA1209139A (en) | 1986-08-05 |
ZA835469B (en) | 1984-05-30 |
IL69340A (en) | 1986-09-30 |
EP0100033A1 (de) | 1984-02-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHB | Application shelved due to non-payment |