DK3436007T3 - Beta-amino-pateamin-A-derivater og fremgangsmåder til behandling af kronisk lymfocytisk leukæmi - Google Patents

Beta-amino-pateamin-A-derivater og fremgangsmåder til behandling af kronisk lymfocytisk leukæmi Download PDF

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Publication number
DK3436007T3
DK3436007T3 DK17776804.1T DK17776804T DK3436007T3 DK 3436007 T3 DK3436007 T3 DK 3436007T3 DK 17776804 T DK17776804 T DK 17776804T DK 3436007 T3 DK3436007 T3 DK 3436007T3
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Denmark
Prior art keywords
pateamine
beta
derivatives
amino
methods
Prior art date
Application number
DK17776804.1T
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Danish (da)
English (en)
Inventor
Daniel Romo
Kenneth Hull
Mingzhao Zhu
Omar Robles
Original Assignee
Texas A & M Univ Sys
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Publication date
Application filed by Texas A & M Univ Sys filed Critical Texas A & M Univ Sys
Application granted granted Critical
Publication of DK3436007T3 publication Critical patent/DK3436007T3/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/429Thiazoles condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK17776804.1T 2016-03-31 2017-03-31 Beta-amino-pateamin-A-derivater og fremgangsmåder til behandling af kronisk lymfocytisk leukæmi DK3436007T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662316299P 2016-03-31 2016-03-31
PCT/US2017/025448 WO2017173313A1 (en) 2016-03-31 2017-03-31 Beta-amimo pateamine a derivatives and methods for treating chronic lymphocytic leukemia

Publications (1)

Publication Number Publication Date
DK3436007T3 true DK3436007T3 (da) 2022-03-14

Family

ID=59965302

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17776804.1T DK3436007T3 (da) 2016-03-31 2017-03-31 Beta-amino-pateamin-A-derivater og fremgangsmåder til behandling af kronisk lymfocytisk leukæmi

Country Status (7)

Country Link
US (1) US10889596B2 (https=)
EP (1) EP3436007B1 (https=)
JP (1) JP6993348B2 (https=)
CA (1) CA3018192C (https=)
DK (1) DK3436007T3 (https=)
ES (1) ES2913210T3 (https=)
WO (1) WO2017173313A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024254195A1 (en) * 2023-06-06 2024-12-12 Baylor University Methods for treating pancreatic cancer with a combination of des-methyl pateamine a and a class 1 hdac inhibitor

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0647645A1 (en) 1993-10-12 1995-04-12 Pharma Mar, S.A. Novel antitumoral and antiviral compound
US7737134B2 (en) 2002-03-13 2010-06-15 The Texas A & M University System Anticancer agents and use
US7230021B2 (en) 2002-03-13 2007-06-12 The Texas A&M University System Potent, simplified derivatives of pateamine A
US20130053994A1 (en) * 2011-08-31 2013-02-28 General Electric Company Method and apparatus for monitoring radiopharmaceutical processing
WO2013152299A2 (en) * 2012-04-06 2013-10-10 University Of North Carolina At Chapel Hill Inhibitors of eif4a and derivatives of pateamine a with antiviral activity and use

Also Published As

Publication number Publication date
WO2017173313A1 (en) 2017-10-05
EP3436007A1 (en) 2019-02-06
EP3436007A4 (en) 2019-10-09
EP3436007B1 (en) 2022-03-02
US10889596B2 (en) 2021-01-12
JP2019510070A (ja) 2019-04-11
CA3018192A1 (en) 2017-10-05
JP6993348B2 (ja) 2022-02-15
US20190177339A1 (en) 2019-06-13
CA3018192C (en) 2025-05-06
ES2913210T3 (es) 2022-06-01

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