DK3414343T3 - Fremgangsmåder til vurdering af behandlingsresponset hos tnbc-patienter på neoadjuvanskemoterapi ved analyse af cpg-methylering - Google Patents

Fremgangsmåder til vurdering af behandlingsresponset hos tnbc-patienter på neoadjuvanskemoterapi ved analyse af cpg-methylering Download PDF

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Publication number
DK3414343T3
DK3414343T3 DK17705091.1T DK17705091T DK3414343T3 DK 3414343 T3 DK3414343 T3 DK 3414343T3 DK 17705091 T DK17705091 T DK 17705091T DK 3414343 T3 DK3414343 T3 DK 3414343T3
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Denmark
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neoadjuvan
chemotherapy
analysis
methods
treatment response
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DK17705091.1T
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English (en)
Inventor
Manfred Schmitt
Olaf G Wilhelm
Rudolf Napieralski
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Therawis Diagnostics Gmbh
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/154Methylation markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK17705091.1T 2016-02-11 2017-02-10 Fremgangsmåder til vurdering af behandlingsresponset hos tnbc-patienter på neoadjuvanskemoterapi ved analyse af cpg-methylering DK3414343T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16155279 2016-02-11
PCT/EP2017/053070 WO2017137601A1 (en) 2016-02-11 2017-02-10 Methods for assessing the treatment response of tnbc patients to neo-adjuvant chemotherapy by analysing cpg methylation

Publications (1)

Publication Number Publication Date
DK3414343T3 true DK3414343T3 (da) 2024-05-06

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Family Applications (1)

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DK17705091.1T DK3414343T3 (da) 2016-02-11 2017-02-10 Fremgangsmåder til vurdering af behandlingsresponset hos tnbc-patienter på neoadjuvanskemoterapi ved analyse af cpg-methylering

Country Status (4)

Country Link
US (1) US11230737B2 (da)
EP (1) EP3414343B1 (da)
DK (1) DK3414343T3 (da)
WO (1) WO2017137601A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3802882A1 (en) * 2018-06-04 2021-04-14 Universitat de València In vitro method for the prediction of response to chemotherapy in triple negative breast cancer patients
CN111621576B (zh) * 2020-06-18 2022-11-08 深圳市计量质量检测研究院(国家高新技术计量站、国家数字电子产品质量监督检验中心) 用于检测油鱼的rpa引物和探针及检测方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1561821B1 (en) 2003-12-11 2011-02-16 Epigenomics AG Prognostic markers for prediction of treatment response and/or survival of breast cell proliferative disorder patients
EP1945806B1 (en) 2005-09-21 2013-02-27 Epigenomics AG Markers for the prediction of outcome of anthracycline treatment
WO2015169857A1 (en) 2014-05-07 2015-11-12 Université Libre de Bruxelles Breast cancer epigenetic markers useful in anthracycline treatment prognosis
EP3246413A1 (en) * 2016-05-20 2017-11-22 Klinikum rechts der Isar der Technischen Universität München A method for predicting a breast cancer patient's response to anthracycline treatment

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Publication number Publication date
US11230737B2 (en) 2022-01-25
US20190323084A1 (en) 2019-10-24
EP3414343B1 (en) 2024-04-03
WO2017137601A1 (en) 2017-08-17
EP3414343A1 (en) 2018-12-19

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