DK3338791T3 - Terapeutisk dosering af en neuregulin i behandling eller profylaxis af hjertesvigt - Google Patents

Terapeutisk dosering af en neuregulin i behandling eller profylaxis af hjertesvigt Download PDF

Info

Publication number
DK3338791T3
DK3338791T3 DK17209369.2T DK17209369T DK3338791T3 DK 3338791 T3 DK3338791 T3 DK 3338791T3 DK 17209369 T DK17209369 T DK 17209369T DK 3338791 T3 DK3338791 T3 DK 3338791T3
Authority
DK
Denmark
Prior art keywords
neureguline
prophylaxis
treatment
heart failure
therapeutic dosage
Prior art date
Application number
DK17209369.2T
Other languages
Danish (da)
English (en)
Inventor
Anthony Caggiano
Anindita Ganguly
Jennifer Iaci
Tom Parry
Original Assignee
Acorda Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acorda Therapeutics Inc filed Critical Acorda Therapeutics Inc
Application granted granted Critical
Publication of DK3338791T3 publication Critical patent/DK3338791T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1883—Neuregulins, e.g.. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK17209369.2T 2008-07-17 2009-07-17 Terapeutisk dosering af en neuregulin i behandling eller profylaxis af hjertesvigt DK3338791T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13517108P 2008-07-17 2008-07-17
EP09813336.6A EP2320933B1 (en) 2008-07-17 2009-07-17 Therapeutic dosing of a neuregulin or a subsequence thereof for treatment or prophylaxis of heart failure

Publications (1)

Publication Number Publication Date
DK3338791T3 true DK3338791T3 (da) 2019-12-16

Family

ID=42005671

Family Applications (2)

Application Number Title Priority Date Filing Date
DK17209369.2T DK3338791T3 (da) 2008-07-17 2009-07-17 Terapeutisk dosering af en neuregulin i behandling eller profylaxis af hjertesvigt
DK09813336.6T DK2320933T3 (en) 2008-07-17 2009-07-17 THERAPEUTIC DOSAGE OF A NEUREGULIN OR A SUBSEQUENT THEREOF FOR TREATMENT OR PROPHYLAXY OF HEART FAILURE

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK09813336.6T DK2320933T3 (en) 2008-07-17 2009-07-17 THERAPEUTIC DOSAGE OF A NEUREGULIN OR A SUBSEQUENT THEREOF FOR TREATMENT OR PROPHYLAXY OF HEART FAILURE

Country Status (13)

Country Link
US (5) US20110166068A1 (cg-RX-API-DMAC7.html)
EP (3) EP2320933B1 (cg-RX-API-DMAC7.html)
JP (5) JP5797112B2 (cg-RX-API-DMAC7.html)
CN (3) CN102159236A (cg-RX-API-DMAC7.html)
AU (3) AU2009292216B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0916442A2 (cg-RX-API-DMAC7.html)
CA (1) CA2731113A1 (cg-RX-API-DMAC7.html)
DK (2) DK3338791T3 (cg-RX-API-DMAC7.html)
ES (2) ES2664394T3 (cg-RX-API-DMAC7.html)
MX (2) MX2011000696A (cg-RX-API-DMAC7.html)
PL (2) PL2320933T3 (cg-RX-API-DMAC7.html)
RU (4) RU2536938C2 (cg-RX-API-DMAC7.html)
WO (1) WO2010030317A2 (cg-RX-API-DMAC7.html)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010030317A2 (en) 2008-07-17 2010-03-18 Acorda Therapeutics, Inc. Therapeutic dosing of a neuregulin or a subsequence thereof for treatment or prophylaxis of heart failure
EP3777878A1 (en) 2008-08-15 2021-02-17 Acorda Therapeutics, Inc. Compositions and methods for treatment during non-acute periods following cns neurological injury
JP5743898B2 (ja) 2008-11-28 2015-07-01 ゼンサン （シャンハイ） サイエンス アンド テクノロジー リミテッド ニューレグリンペプチド及びその使用
EP3235504B1 (en) 2009-10-14 2019-09-18 Acorda Therapeutics, Inc. Use of a neuregulin to treat peripheral nerve injury
WO2013053076A1 (en) 2011-10-10 2013-04-18 Zensun （Shanghai）Science & Technology Limited Compositions and methods for treating heart failure
EP3278811B1 (en) * 2012-03-30 2020-12-02 Acorda Therapeutics, Inc. Use of ggf2 to treat neuropathic pain upon peripheral nerve injury
US20160129084A1 (en) * 2013-03-06 2016-05-12 Acorda Therapeutics, Inc. Therapeutic Dosing of a Neuregulin or a Fragment Thereof for Treatment or Prophylaxis of Heart Failure
CN105611955A (zh) 2013-05-22 2016-05-25 上海泽生科技开发有限公司 缓释纽兰格林治疗心力衰竭
CN104758922A (zh) 2014-01-03 2015-07-08 上海泽生科技开发有限公司 纽兰格林制剂的配方
CN105561298A (zh) * 2014-10-17 2016-05-11 上海泽生科技开发有限公司 神经调节蛋白用于预防、治疗或延迟射血分数保留的心力衰竭的方法和组合物
CN108474787A (zh) 2015-09-25 2018-08-31 道格拉斯.B.索耶 用于治疗心脏损伤的方法
EP3445386B1 (en) * 2016-04-19 2020-08-26 Leibniz-Institut für Alternsforschung - Fritz-Lipmann-Institut e.V. (FLI) Neuregulin for the treatment and/or prevention of tumors of the nervous system
CN110835368A (zh) * 2018-08-15 2020-02-25 上海泽生科技开发股份有限公司 神经调节蛋白多肽片段及其用途
AR121035A1 (es) 2019-04-01 2022-04-13 Lilly Co Eli Compuestos de neuregulina-4 y métodos de uso
AU2020348436A1 (en) * 2019-09-16 2022-04-07 Zensun (Shanghai) Science & Technology, Co., Ltd. Recombinant human neuregulin derivatives and use thereof
WO2023070078A1 (en) * 2021-10-22 2023-04-27 The Research Institute At Nationwide Children's Hospital Neuregulin for protection against respiratory viral infection and post-viral disease

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5530109A (en) 1991-04-10 1996-06-25 Ludwig Institute For Cancer Research DNA encoding glial mitogenic factors
US5716930A (en) 1991-04-10 1998-02-10 Ludwig Institute For Cancer Research Glial growth factors
US7115554B1 (en) * 1993-05-06 2006-10-03 Acorda Therapeutics, Inc. Methods of increasing myotube formation or survival or muscle cell mitogenesis differentiation or survival using neuregulin GGF III
US6087323A (en) 1992-04-03 2000-07-11 Cambridge Neuroscience, Inc. Use of neuregulins as modulators of cellular communication
US7037888B1 (en) 1992-04-03 2006-05-02 Acorda Therapeutics, Inc. Methods for treating muscle diseases and disorders
US5811098A (en) * 1992-11-24 1998-09-22 Bristol-Myers Squibb Company Antibodies to HER4, human receptor tyrosine kinase
US5912326A (en) 1995-09-08 1999-06-15 President And Fellows Of Harvard College Cerebellum-derived growth factors
US6136558A (en) * 1997-02-10 2000-10-24 Genentech, Inc. Heregulin variants
US6051401A (en) 1998-07-28 2000-04-18 Bayer Corporation Methods and constructs for protein expression
SI1115417T1 (sl) 1998-09-25 2006-08-31 Cubist Pharm Inc Uporaba daptomicina
AUPP785098A0 (en) * 1998-12-21 1999-01-21 Victor Chang Cardiac Research Institute, The Treatment of heart disease
US6635249B1 (en) 1999-04-23 2003-10-21 Cenes Pharmaceuticals, Inc. Methods for treating congestive heart failure
CN1138785C (zh) * 1999-06-04 2004-02-18 周明东 生长因子神经调节蛋白及其类似物的新应用
WO2001034174A2 (en) 1999-11-12 2001-05-17 Entremed, Inc. Methods for administration of therapeutic agents on an antiangiogenic schedule
ES2370875T3 (es) 2000-05-23 2011-12-23 Acorda Therapeutics, Inc. Moléculas de ácido nucleico nrg-2, polipéptidos y métodos de diagnóstico y terapéuticos.
CU23157A1 (es) * 2001-01-03 2006-07-18 Ct Ingenieria Genetica Biotech COMPOSICION FARMACéUTICA PARA EL TRATAMIENTO DEL DANO TISULAR DEBIDO A FALTA DE IRRIGACION SANGUINEA ARTERIAL
EP1569689A4 (en) 2002-01-18 2009-08-05 Novartis Vaccines & Diagnostic IL2 / ANTI-HER2-ANTIBODY COMBINATION THERAPY AGAINST CANCER, which is characterized by overexpression of the HER2-RECEPTOR PROTEIN
WO2003099320A1 (en) * 2002-05-24 2003-12-04 Zensun (Shanghai) Sci-Tech.Ltd Neuregulin based methods and compositions for treating viral myocarditis and dilated cardiomyopathy
US20070032557A1 (en) * 2005-02-18 2007-02-08 Matti Kivikko Method for administering levosimendan
AR053690A1 (es) 2005-03-23 2007-05-16 Pfizer Prod Inc Terapia de cancer de prostata con anticuerpos contra ctla4 y terapia hormonal
US7776817B2 (en) 2005-09-02 2010-08-17 Morehouse School Of Medicine Neuregulins for prevention and treatment of damage from acute assault on vascular and neuronal tissue and as regulators of neuronal stem cell migration
US20070213264A1 (en) * 2005-12-02 2007-09-13 Mingdong Zhou Neuregulin variants and methods of screening and using thereof
EP2918283B1 (en) * 2005-12-30 2018-01-31 Zensun (Shanghai) Science & Technology, Co., Ltd. Extended release of neuregulin for improved cardiac function
US8410050B2 (en) 2008-02-29 2013-04-02 Acorda Therapeutics, Inc. Method for achieving desired glial growth factor 2 plasma levels
WO2010030317A2 (en) 2008-07-17 2010-03-18 Acorda Therapeutics, Inc. Therapeutic dosing of a neuregulin or a subsequence thereof for treatment or prophylaxis of heart failure
EP3235504B1 (en) 2009-10-14 2019-09-18 Acorda Therapeutics, Inc. Use of a neuregulin to treat peripheral nerve injury
WO2012021818A2 (en) 2010-08-13 2012-02-16 Georgetown University Ggf2 and methods of use
EP3278811B1 (en) 2012-03-30 2020-12-02 Acorda Therapeutics, Inc. Use of ggf2 to treat neuropathic pain upon peripheral nerve injury

Also Published As

Publication number Publication date
US20130324466A1 (en) 2013-12-05
JP2022023208A (ja) 2022-02-07
US20110166068A1 (en) 2011-07-07
RU2719199C1 (ru) 2020-04-17
JP2011528353A (ja) 2011-11-17
JP2017200949A (ja) 2017-11-09
EP3338791A1 (en) 2018-06-27
PL2320933T3 (pl) 2018-07-31
US20160113999A1 (en) 2016-04-28
EP3338791B1 (en) 2019-09-18
EP3632459A1 (en) 2020-04-08
JP2019196370A (ja) 2019-11-14
CN102159236A (zh) 2011-08-17
CN104623633A (zh) 2015-05-20
HK1256637A1 (en) 2019-09-27
JP6189879B2 (ja) 2017-08-30
EP2320933A4 (en) 2013-02-27
CN107019794B (zh) 2021-03-12
US9198951B2 (en) 2015-12-01
JP2015129137A (ja) 2015-07-16
US20200009228A1 (en) 2020-01-09
AU2009292216B2 (en) 2015-03-05
EP2320933B1 (en) 2017-12-27
US9956266B2 (en) 2018-05-01
US11235031B2 (en) 2022-02-01
AU2009292216A1 (en) 2010-03-18
AU2015202877B2 (en) 2017-03-09
CN107019794A (zh) 2017-08-08
AU2017203528A1 (en) 2017-06-15
RU2536938C2 (ru) 2014-12-27
RU2020111236A3 (cg-RX-API-DMAC7.html) 2021-09-21
ES2763184T3 (es) 2020-05-27
US20180280477A1 (en) 2018-10-04
ES2664394T3 (es) 2018-04-19
BRPI0916442A2 (pt) 2018-06-19
WO2010030317A2 (en) 2010-03-18
AU2015202877A1 (en) 2015-06-18
MX384378B (es) 2025-03-14
JP5797112B2 (ja) 2015-10-21
PL3338791T3 (pl) 2020-04-30
RU2020111236A (ru) 2021-09-21
MX2011000696A (es) 2011-07-29
CA2731113A1 (en) 2010-03-18
RU2014141514A (ru) 2016-05-10
DK2320933T3 (en) 2018-04-16
EP2320933A1 (en) 2011-05-18
RU2698090C2 (ru) 2019-08-22
RU2011105821A (ru) 2012-08-27

Similar Documents

Publication Publication Date Title
DK3338791T3 (da) Terapeutisk dosering af en neuregulin i behandling eller profylaxis af hjertesvigt
FR18C1043I2 (fr) Therapie antivirale
DK2448637T4 (da) Anvendelse af et phytocannabinoid eller en kombination af phytocannabinoider i behandling af epilepsi
DK2222272T3 (da) Behandling af luftvejssygdom
NO2019010I1 (no) Eravasyklin eller farmasøytisk akseptable salter derav
CY2014006I2 (el) Μεθοδοι θεραπευτικης αγωγης χρησιμοποιωντας γλυκοπεγκυλιωμενο g-csf
DK2488242T3 (da) Medicinsk indåndingsmaske
RU2557654C3 (ru) Терапевтические агенты для снижения уровней паратиреоидного гормона
DK3967274T4 (da) Hjerteklapanordninger med stent
DK2808024T3 (da) Bifidobakterier til behandling af kongestiv hjerteinsufficiens
BRPI1011441A2 (pt) cinta corporal terapeutica
HRP20170972T1 (hr) Kombinacijska terapija afukoziliranog cd20-protutijela s bendamustinom
HUE045367T2 (hu) Kombinált terápia diabétesz kezelésére
DK2452281T3 (da) Fremgangsmåde til at forudsige virkningen af lægemidler i en patient
DK2538986T3 (da) Intraartikulært supplement til anvendelse til behandling af ledsygdomme og -skader
EP2247297A4 (en) THERAPEUTIC TREATMENT OF LUNG DISEASES
DK2252317T3 (da) Behandling af makuladegeneration
ZA201308391B (en) Use of cathepsin k inhibition for the treatment and/or prophylaxis of pulmonary hypertension and/or heart failure
EP2496194A4 (en) EXOTHERMIC NATURAL THERAPEUTIC MASSAGE SHELLS
DK3211005T3 (da) Terapeutisk anvendelse af specifik ligand i msrv-associerede sygdomme
PL2320878T3 (pl) Monoterpeny do leczenia chorób dróg oddechowych, w szczególności chorób oskrzelowo-płucnych
FI20096402A0 (fi) Veriryhmästatuksen käyttö II
DK2323686T3 (da) Adiponectin til behandling af lungesygdom
BRPI1013903A2 (pt) tratamentos terapêuticos utilizando centaquina
BRPI1009322A2 (pt) dose de ave5026 para o tratamento de tromboembolia venosa em pacientes com deficiência renal grave