DK3319651T3 - Vaskulariserede in vitro perfusionsindretninger, fremgangsmåder til fremstilling og anvendelser deraf - Google Patents
Vaskulariserede in vitro perfusionsindretninger, fremgangsmåder til fremstilling og anvendelser deraf Download PDFInfo
- Publication number
- DK3319651T3 DK3319651T3 DK16821889.9T DK16821889T DK3319651T3 DK 3319651 T3 DK3319651 T3 DK 3319651T3 DK 16821889 T DK16821889 T DK 16821889T DK 3319651 T3 DK3319651 T3 DK 3319651T3
- Authority
- DK
- Denmark
- Prior art keywords
- vascularized
- manufacture
- methods
- perfusion devices
- vitro perfusion
- Prior art date
Links
- 238000000338 in vitro Methods 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 230000010412 perfusion Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/10—Perfusion
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/16—Microfluidic devices; Capillary tubes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
- C12M25/14—Scaffolds; Matrices
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/069—Vascular Endothelial cells
- C12N5/0691—Vascular smooth muscle cells; 3D culture thereof, e.g. models of blood vessels
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5064—Endothelial cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2513/00—3D culture
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Sustainable Development (AREA)
- Tropical Medicine & Parasitology (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Toxicology (AREA)
- Physics & Mathematics (AREA)
- Clinical Laboratory Science (AREA)
- Dispersion Chemistry (AREA)
- Vascular Medicine (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562188803P | 2015-07-06 | 2015-07-06 | |
US201662279019P | 2016-01-15 | 2016-01-15 | |
PCT/US2016/041034 WO2017007786A1 (en) | 2015-07-06 | 2016-07-06 | Vascularized in vitro perfusion devices, methods of fabricating, and applications thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3319651T3 true DK3319651T3 (da) | 2022-07-18 |
Family
ID=57686133
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK16821889.9T DK3319651T3 (da) | 2015-07-06 | 2016-07-06 | Vaskulariserede in vitro perfusionsindretninger, fremgangsmåder til fremstilling og anvendelser deraf |
Country Status (11)
Country | Link |
---|---|
US (2) | US10392595B2 (da) |
EP (1) | EP3319651B1 (da) |
JP (1) | JP6917975B2 (da) |
KR (1) | KR102530274B1 (da) |
AU (1) | AU2016289944B2 (da) |
CA (1) | CA2991297A1 (da) |
DK (1) | DK3319651T3 (da) |
ES (1) | ES2922905T3 (da) |
IL (1) | IL256673B (da) |
PL (1) | PL3319651T3 (da) |
WO (1) | WO2017007786A1 (da) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10159765B2 (en) * | 2013-10-25 | 2018-12-25 | The Board Of Regents Of The University Of Texas System | Tissue engineered devices and methods for making same |
WO2018132720A1 (en) * | 2017-01-13 | 2018-07-19 | The Penn State Research Foundation | Organ models |
AU2018233180B2 (en) * | 2017-03-15 | 2023-12-14 | Aspect Biosystems Ltd. | Systems and methods for printing a fiber structure |
CA3059983C (en) * | 2017-04-14 | 2023-09-05 | Advanced Solutions Life Sciences, Llc | Vascularized in vitro arrays of living cells |
US11035740B1 (en) * | 2017-07-31 | 2021-06-15 | Prasidiux, Llc | Stimulus indicating device employing thermoreversible amphiphilic gels |
EP3684915A4 (en) * | 2017-09-19 | 2021-06-30 | Cornell University | MANUFACTURING OF A BIOMIMETIC PLATFORM SYSTEM AND METHODS OF USE |
GB201801582D0 (en) * | 2018-01-31 | 2018-03-14 | Univ Leuven Kath | Devices and methods for three-dimensional growth of cells |
KR102441083B1 (ko) | 2018-03-08 | 2022-09-06 | 현대자동차주식회사 | 크랭크샤프트용 댐퍼풀리 |
EP3775154A4 (en) * | 2018-03-26 | 2021-12-22 | The Trustees of the University of Pennsylvania | SYSTEMS AND METHODS FOR A MULTI-WAY VASCULAR SYSTEM |
CN110607271B (zh) * | 2018-06-14 | 2023-01-20 | 中国科学院大连化学物理研究所 | 一种基于微加工技术的体外血管化3d组织的制备方法 |
CN110713921B (zh) * | 2018-07-13 | 2022-12-20 | 复旦大学 | 一套体外动态的药物代谢孵育系统 |
SE543308C2 (en) * | 2018-12-11 | 2020-11-24 | Cellink Ab | Microfluidic device facilitating perfusion of mammalian and human tissue constructs |
WO2020185576A1 (en) * | 2019-03-08 | 2020-09-17 | Advanced Solutions Life Sciences, Llc | Modular and expandable low flow pumping assemblies |
WO2020205567A1 (en) * | 2019-03-29 | 2020-10-08 | Advanced Solutions Life Sciences, Llc | Systems and methods for biomedical object segmentation |
JP2022536892A (ja) * | 2019-06-18 | 2022-08-22 | スリーディー バイオラブズ,エルエルシー | マイクロチャネル導管ネットワークデバイスの製作およびマイクロチャネルへの播種のためのシステムならびに方法 |
GB202004177D0 (en) * | 2020-03-16 | 2020-05-06 | Imp College Innovations Ltd | Device for perfusion and preservation of tissue specimens ex vivo |
EP4146783A1 (en) * | 2020-05-05 | 2023-03-15 | 3D Systems, Inc. | Microcosm bio-scaffold and applications thereof |
KR102520786B1 (ko) * | 2020-05-27 | 2023-04-13 | 한국재료연구원 | 3차원 구조체 내부 관류 가능 미세 혈관 생성을 위한 바이오리액팅 시스템 |
WO2022015854A2 (en) * | 2020-07-15 | 2022-01-20 | Advanced Solutions Life Sciences, Llc | Methods of identifying therapeutic targets for treating angiogenesis |
US20220135951A1 (en) * | 2020-11-04 | 2022-05-05 | The University Of Kansas | Renal tube assay device and methods of manufacture and use |
WO2022155337A1 (en) * | 2021-01-15 | 2022-07-21 | The Trustees Of Indiana University | A device having a support structure for creating a hollow, three-dimensional organoids and cultures |
US20220284832A1 (en) * | 2021-03-05 | 2022-09-08 | Advanced Solutions Life Sciences, Llc | Models and methods to establish perfused vascularized tissues in three-dimensional in vitro culture |
AU2022351688A1 (en) * | 2021-09-24 | 2024-04-04 | 3D Systems, Inc. | Manifolds, systems and methods for conducting biological studies under flow |
WO2023133523A2 (en) * | 2022-01-07 | 2023-07-13 | South Dakota Board Of Regents | Physiologically-relevant, serum-free in vitro angiogenesis platform |
WO2023140719A1 (ko) * | 2022-01-24 | 2023-07-27 | 울산과학기술원 | 바이오 스캐폴드 제조용 미세유체 장치 및 이의 용도 |
WO2024044348A1 (en) * | 2022-08-26 | 2024-02-29 | Chunguang Xia | System and method for perfusion bioreactor for 3d cell culture |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH02261375A (ja) * | 1989-04-03 | 1990-10-24 | Terumo Corp | 血管新生活性を有する細胞および血管新生活性物ならびにその製造方法 |
US7052829B2 (en) | 2001-03-30 | 2006-05-30 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Prevascularized constructs for implantation to provide blood perfusion |
WO2002078439A2 (en) | 2001-03-30 | 2002-10-10 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Prevascularized constructs for implantation to provide blood perfusion |
WO2003078586A2 (en) | 2002-03-12 | 2003-09-25 | The Regents Of The University Of California | Vascularized tissue for transplantation |
US8663625B2 (en) | 2004-10-15 | 2014-03-04 | Cornell Research Foundation | Diffusively permeable monolithic biomaterial with embedded microfluidic channels |
US7622298B2 (en) * | 2006-03-24 | 2009-11-24 | Norits, Inc. | Method for creating perfusable microvessel systems |
US8003388B2 (en) * | 2006-03-24 | 2011-08-23 | Nortis, Inc. | Method for creating perfusable microvessel systems |
ES2639183T3 (es) * | 2007-09-19 | 2017-10-25 | The Charles Stark Draper Laboratory, Inc. | Estructuras microfluídicas con sección transversal circular |
WO2010033820A1 (en) * | 2008-09-19 | 2010-03-25 | University Of Louisville Research Foundation, Inc. | Bioreactors, systems, and methods for vascularizing tissue constructs |
WO2011115974A1 (en) * | 2010-03-15 | 2011-09-22 | Indiana University Research And Technology Corporation | Engineered lumenized vascular networks and support matrix |
US20150231182A1 (en) | 2012-09-07 | 2015-08-20 | University Of Louisville Research Foundation, Inc. | Cell systems and methods for delivering disease-specific therapies |
JP2015062392A (ja) * | 2013-09-26 | 2015-04-09 | 学校法人東京電機大学 | 毛細血管の製造方法および毛細血管の製造装置 |
CN106163581B (zh) | 2013-11-05 | 2019-10-25 | 哈佛学院院长及董事 | 打印具有包埋的脉管系统的组织构建体的方法 |
EP3265104A4 (en) | 2015-03-03 | 2018-11-07 | President and Fellows of Harvard College | Methods of generating functional human tissue |
-
2016
- 2016-07-06 DK DK16821889.9T patent/DK3319651T3/da active
- 2016-07-06 WO PCT/US2016/041034 patent/WO2017007786A1/en active Application Filing
- 2016-07-06 US US15/202,675 patent/US10392595B2/en active Active
- 2016-07-06 AU AU2016289944A patent/AU2016289944B2/en active Active
- 2016-07-06 EP EP16821889.9A patent/EP3319651B1/en active Active
- 2016-07-06 PL PL16821889.9T patent/PL3319651T3/pl unknown
- 2016-07-06 JP JP2018500730A patent/JP6917975B2/ja active Active
- 2016-07-06 KR KR1020187003591A patent/KR102530274B1/ko active IP Right Grant
- 2016-07-06 ES ES16821889T patent/ES2922905T3/es active Active
- 2016-07-06 CA CA2991297A patent/CA2991297A1/en active Pending
-
2017
- 2017-12-31 IL IL256673A patent/IL256673B/en unknown
-
2019
- 2019-07-01 US US16/458,305 patent/US20190330583A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP3319651A4 (en) | 2018-10-24 |
KR102530274B1 (ko) | 2023-05-08 |
JP2018532371A (ja) | 2018-11-08 |
IL256673A (en) | 2018-02-28 |
PL3319651T3 (pl) | 2022-11-14 |
US10392595B2 (en) | 2019-08-27 |
AU2016289944A1 (en) | 2018-02-01 |
US20170009194A1 (en) | 2017-01-12 |
IL256673B (en) | 2021-12-01 |
CA2991297A1 (en) | 2017-01-12 |
EP3319651B1 (en) | 2022-05-11 |
KR20180027553A (ko) | 2018-03-14 |
AU2016289944B2 (en) | 2020-05-07 |
WO2017007786A1 (en) | 2017-01-12 |
ES2922905T3 (es) | 2022-09-21 |
EP3319651A1 (en) | 2018-05-16 |
JP6917975B2 (ja) | 2021-08-11 |
US20190330583A1 (en) | 2019-10-31 |
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