DK3231790T3 - Fremgangsmåde til fremstilling af kationisk lipid - Google Patents
Fremgangsmåde til fremstilling af kationisk lipid Download PDFInfo
- Publication number
- DK3231790T3 DK3231790T3 DK15866734.5T DK15866734T DK3231790T3 DK 3231790 T3 DK3231790 T3 DK 3231790T3 DK 15866734 T DK15866734 T DK 15866734T DK 3231790 T3 DK3231790 T3 DK 3231790T3
- Authority
- DK
- Denmark
- Prior art keywords
- procedure
- cationic lipid
- preparing cationic
- preparing
- lipid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C219/04—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C219/06—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having the hydroxy groups esterified by carboxylic acids having the esterifying carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms of an acyclic saturated carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2014247723 | 2014-12-08 | ||
| PCT/JP2015/084345 WO2016093205A1 (ja) | 2014-12-08 | 2015-12-08 | カチオン性脂質の製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3231790T3 true DK3231790T3 (da) | 2020-01-27 |
Family
ID=56107388
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15866734.5T DK3231790T3 (da) | 2014-12-08 | 2015-12-08 | Fremgangsmåde til fremstilling af kationisk lipid |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9834502B2 (da) |
| EP (1) | EP3231790B1 (da) |
| JP (1) | JP6583682B2 (da) |
| KR (1) | KR102583917B1 (da) |
| CN (1) | CN107001238B (da) |
| DK (1) | DK3231790T3 (da) |
| WO (1) | WO2016093205A1 (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107827762B (zh) * | 2017-11-14 | 2020-10-02 | 苏州东南药业股份有限公司 | 一种(2,3-二油酰基-丙基)三甲基氯化铵及其制备方法和用途 |
| CN114853618A (zh) * | 2022-03-25 | 2022-08-05 | 江苏东南纳米材料有限公司 | 一种阳离子脂质材料dodma的制备方法 |
| WO2024109794A1 (zh) * | 2022-11-24 | 2024-05-30 | 传信生物医药(苏州)有限公司 | 用于递送核酸的新型脂质和脂质纳米颗粒组合物 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5264618A (en) | 1990-04-19 | 1993-11-23 | Vical, Inc. | Cationic lipids for intracellular delivery of biologically active molecules |
| AU7078396A (en) * | 1995-09-27 | 1997-04-30 | Regents Of The University Of California, The | Polyfunctional cationic cytofectins, formulations and methods for generating active cytofectin:polynucleotide transfection complexes |
| US5869715A (en) | 1995-09-27 | 1999-02-09 | The Reagents Of The University Of California | Polyfunctional cationic cytofectins |
| EP1940775A2 (en) * | 2005-08-11 | 2008-07-09 | University of Massachusetts | Methods and compositions for the efficient delivery of therapeutic agents to cells and animals |
| EP2167480A2 (en) | 2007-05-23 | 2010-03-31 | Vical Incorporated | Cationic lipids compositions and methods for enhancing immune responses to vaccines |
| AU2008347251A1 (en) * | 2008-01-02 | 2009-07-16 | Tekmira Pharmaceuticals Corporation | Liver screening method |
| WO2009086558A1 (en) * | 2008-01-02 | 2009-07-09 | Tekmira Pharmaceuticals Corporation | Improved compositions and methods for the delivery of nucleic acids |
| WO2009088891A1 (en) | 2008-01-02 | 2009-07-16 | Alnylam Pharmaceuticals, Inc. | Screening method for selected amino lipid-containing compositions |
| AU2012261276B2 (en) * | 2011-05-20 | 2017-05-25 | Merck Patent Gmbh | Stable crystal modifications of DOTAP chloride |
| JP2013095755A (ja) * | 2011-11-02 | 2013-05-20 | Kyowa Hakko Kirin Co Ltd | カチオン性脂質 |
| CN103880688B (zh) * | 2014-03-14 | 2016-10-05 | 北京大学 | 一种疏水亲油可聚合电解质及其高吸油聚电解质凝胶 |
-
2015
- 2015-12-08 CN CN201580066832.6A patent/CN107001238B/zh active Active
- 2015-12-08 JP JP2015239062A patent/JP6583682B2/ja active Active
- 2015-12-08 DK DK15866734.5T patent/DK3231790T3/da active
- 2015-12-08 KR KR1020177014617A patent/KR102583917B1/ko active IP Right Grant
- 2015-12-08 US US15/529,324 patent/US9834502B2/en active Active
- 2015-12-08 WO PCT/JP2015/084345 patent/WO2016093205A1/ja active Application Filing
- 2015-12-08 EP EP15866734.5A patent/EP3231790B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN107001238B (zh) | 2019-04-26 |
| KR20170094163A (ko) | 2017-08-17 |
| US20170275242A1 (en) | 2017-09-28 |
| JP6583682B2 (ja) | 2019-10-02 |
| JP2016108343A (ja) | 2016-06-20 |
| US9834502B2 (en) | 2017-12-05 |
| EP3231790A1 (en) | 2017-10-18 |
| EP3231790B1 (en) | 2019-11-06 |
| WO2016093205A1 (ja) | 2016-06-16 |
| EP3231790A4 (en) | 2018-07-04 |
| KR102583917B1 (ko) | 2023-10-04 |
| CN107001238A (zh) | 2017-08-01 |
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