DK3226905T3 - Hyaluronan-konjugater med farmaceutisk aktive substanser, fremgangsmåder og sammensætninger - Google Patents

Hyaluronan-konjugater med farmaceutisk aktive substanser, fremgangsmåder og sammensætninger Download PDF

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Publication number
DK3226905T3
DK3226905T3 DK15710918.2T DK15710918T DK3226905T3 DK 3226905 T3 DK3226905 T3 DK 3226905T3 DK 15710918 T DK15710918 T DK 15710918T DK 3226905 T3 DK3226905 T3 DK 3226905T3
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DK
Denmark
Prior art keywords
compositions
methods
active substances
pharmaceutically active
hyaluronan conjugates
Prior art date
Application number
DK15710918.2T
Other languages
English (en)
Inventor
Bengt Lindqvist
Rune Ringom
Original Assignee
Synartro Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synartro Ab filed Critical Synartro Ab
Application granted granted Critical
Publication of DK3226905T3 publication Critical patent/DK3226905T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/12Ophthalmic agents for cataracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DK15710918.2T 2014-02-27 2015-02-21 Hyaluronan-konjugater med farmaceutisk aktive substanser, fremgangsmåder og sammensætninger DK3226905T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461945491P 2014-02-27 2014-02-27
PCT/IB2015/051331 WO2015128787A1 (en) 2014-02-27 2015-02-21 Hyaluronan conjugates with pharmaceutically active substances, methods and compositions

Publications (1)

Publication Number Publication Date
DK3226905T3 true DK3226905T3 (da) 2022-01-24

Family

ID=52693002

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15710918.2T DK3226905T3 (da) 2014-02-27 2015-02-21 Hyaluronan-konjugater med farmaceutisk aktive substanser, fremgangsmåder og sammensætninger

Country Status (14)

Country Link
US (3) US10660906B2 (da)
EP (2) EP3988121A1 (da)
CA (1) CA2974611C (da)
CY (1) CY1125005T1 (da)
DK (1) DK3226905T3 (da)
ES (1) ES2905606T3 (da)
HR (1) HRP20220176T1 (da)
HU (1) HUE057871T2 (da)
LT (1) LT3226905T (da)
PL (1) PL3226905T3 (da)
PT (1) PT3226905T (da)
RS (1) RS62909B1 (da)
SI (1) SI3226905T1 (da)
WO (1) WO2015128787A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015128787A1 (en) * 2014-02-27 2015-09-03 Pharmalink Ab Hyaluronan conjugates with pharmaceutically active substances, methods and compositions
KR20200113036A (ko) * 2017-03-14 2020-10-05 세이가가쿠 고교 가부시키가이샤 관절 질환 처치용 조성물 및 그것을 포함하는 키트
TWI840445B (zh) 2018-11-16 2024-05-01 日商生化學工業股份有限公司 水性組成物及其用途、注射套組、醫藥組成物及其製造方法、生成抑制方法
CN113750255B (zh) * 2021-09-30 2023-10-31 大连民族大学 环境响应型透明质酸-鬼臼毒素前药胶束及其制备方法和应用
WO2024038088A1 (en) 2022-08-16 2024-02-22 Synartro Ab Liquid formulations

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE442820B (sv) 1984-06-08 1986-02-03 Pharmacia Ab Gel av tverbunden hyaluronsyra for anvendning som glaskroppssubstitut
IT1281877B1 (it) 1995-05-10 1998-03-03 Fidia Advanced Biopolymers Srl Sali di metalli pesanti di succinil derivati dell'acido ialuronico e loro impiego come potenziali agenti terapeutici
IT1281876B1 (it) 1995-05-10 1998-03-03 Fidia Advanced Biopolymers Srl Acido ialuronico e suoi derivati esterei per la preparazione di matrici per il rilascio controllato di farmaci.
IT1294797B1 (it) * 1997-07-28 1999-04-15 Fidia Advanced Biopolymers Srl Uso dei derivati dell'acido ialuronico nella preparazione di biomateriali aventi attivita' emostatica fisica e tamponante
DE19882079D2 (de) 1997-12-31 2000-11-16 Schleifring Und App Bau Gmbh Anordnung zur Übertragung elektrischer Signale und/oder Energie
AU2001267852B2 (en) * 2000-06-30 2006-01-19 Msd K.K. Novel pyrazinone derivatives
US20030049253A1 (en) * 2001-08-08 2003-03-13 Li Frank Q. Polymeric conjugates for delivery of MHC-recognized epitopes via peptide vaccines
JP2004099581A (ja) * 2002-09-09 2004-04-02 Masashi Takahashi 抗炎症剤
AU2005203988B2 (en) 2004-01-07 2010-11-11 Seikagaku Corporation Hyaluronic acid derivative and drug containing the same
JP5043364B2 (ja) * 2006-05-01 2012-10-10 生化学工業株式会社 多糖誘導体の製造方法
IE20070900A1 (en) 2007-12-12 2009-06-24 Eurand Pharmaceuticals Ltd New anticancer conjugates
US20130053405A1 (en) * 2009-10-06 2013-02-28 Ulrich Hersel Carrier linked paliperidone prodrugs
KR20140103099A (ko) * 2011-10-12 2014-08-25 아센디스 파마 옵탈몰로지 디비젼 에이/에스 안구 병태의 예방 및 치료
GB2510587B (en) * 2013-02-07 2020-05-20 Orthopaedic Res Uk Biospecific agents for bone
WO2015128787A1 (en) 2014-02-27 2015-09-03 Pharmalink Ab Hyaluronan conjugates with pharmaceutically active substances, methods and compositions

Also Published As

Publication number Publication date
PT3226905T (pt) 2022-01-19
RS62909B1 (sr) 2022-03-31
CY1125005T1 (el) 2023-01-05
WO2015128787A1 (en) 2015-09-03
US11229656B2 (en) 2022-01-25
US20200237783A1 (en) 2020-07-30
LT3226905T (lt) 2022-03-10
SI3226905T1 (sl) 2022-04-29
ES2905606T3 (es) 2022-04-11
EP3226905A1 (en) 2017-10-11
CA2974611C (en) 2022-07-12
EP3226905B1 (en) 2021-12-22
HRP20220176T1 (hr) 2022-04-29
PL3226905T3 (pl) 2022-04-19
HUE057871T2 (hu) 2022-06-28
US11642357B2 (en) 2023-05-09
US20160367684A1 (en) 2016-12-22
EP3988121A1 (en) 2022-04-27
CA2974611A1 (en) 2015-09-03
US10660906B2 (en) 2020-05-26
US20220168320A1 (en) 2022-06-02

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