DK3216791T3 - Polymorft stof på basis af yonkenafil-hydrochlorid, fremgangsmåde til fremstilling heraf samt sammensætning og anvendelse heraf - Google Patents
Polymorft stof på basis af yonkenafil-hydrochlorid, fremgangsmåde til fremstilling heraf samt sammensætning og anvendelse heraf Download PDFInfo
- Publication number
- DK3216791T3 DK3216791T3 DK15869159.2T DK15869159T DK3216791T3 DK 3216791 T3 DK3216791 T3 DK 3216791T3 DK 15869159 T DK15869159 T DK 15869159T DK 3216791 T3 DK3216791 T3 DK 3216791T3
- Authority
- DK
- Denmark
- Prior art keywords
- procedure
- manufacture
- composition
- substance based
- polymorphic substance
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Pulmonology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Gynecology & Obstetrics (AREA)
- Ophthalmology & Optometry (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Pregnancy & Childbirth (AREA)
- Otolaryngology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201410799600.9A CN104530054B (zh) | 2014-12-19 | 2014-12-19 | 盐酸优克那非的多晶型物及其制备方法 |
PCT/CN2015/095059 WO2016095650A1 (zh) | 2014-12-19 | 2015-11-19 | 盐酸优克那非的多晶型物及其制备方法、组合物和用途 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3216791T3 true DK3216791T3 (da) | 2022-07-11 |
Family
ID=52845723
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK15869159.2T DK3216791T3 (da) | 2014-12-19 | 2015-11-19 | Polymorft stof på basis af yonkenafil-hydrochlorid, fremgangsmåde til fremstilling heraf samt sammensætning og anvendelse heraf |
Country Status (12)
Country | Link |
---|---|
US (1) | US9884870B2 (da) |
EP (1) | EP3216791B1 (da) |
JP (1) | JP6473820B2 (da) |
KR (1) | KR102003847B1 (da) |
CN (1) | CN104530054B (da) |
CA (1) | CA2971484C (da) |
DK (1) | DK3216791T3 (da) |
ES (1) | ES2918948T3 (da) |
PL (1) | PL3216791T3 (da) |
PT (1) | PT3216791T (da) |
RU (1) | RU2672249C9 (da) |
WO (1) | WO2016095650A1 (da) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104530054B (zh) | 2014-12-19 | 2018-01-19 | 扬子江药业集团有限公司 | 盐酸优克那非的多晶型物及其制备方法 |
CN106333953A (zh) * | 2015-07-08 | 2017-01-18 | 珠海津之敦医药科技有限公司 | 尤克那非新用途 |
CN116478309B (zh) * | 2023-05-19 | 2024-05-17 | 青海大学 | 锁阳精多糖、锁阳多糖化合物及制备方法和应用 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2097384C1 (ru) * | 1989-10-31 | 1997-11-27 | Биокрист Фармасьютикалз Инк. | Производные 2-амино-7-(chr2r3)-3н,5н-пирроло[3,2-d]-пиримидин-4-она, способы их получения и способ селективного ингибирования пролиферации т-лимфоцитов млекопитающего и не оказывающий воздействия на b-лимфоциты |
CN100374441C (zh) * | 2003-06-06 | 2008-03-12 | 天津倍方科技发展有限公司 | 二氢吡咯[2,3-d]嘧啶-4-酮衍生物,其制备方法及其制药用途 |
JP2009518415A (ja) * | 2005-12-05 | 2009-05-07 | バイオマリン ファーマシューティカル インコーポレイテッド | 疾患の処置のための方法および組成物 |
CN102970965A (zh) * | 2010-04-05 | 2013-03-13 | Sk化学公司 | 含有pde5抑制剂的减少皮肤皱纹的合成物 |
CN104530054B (zh) * | 2014-12-19 | 2018-01-19 | 扬子江药业集团有限公司 | 盐酸优克那非的多晶型物及其制备方法 |
-
2014
- 2014-12-19 CN CN201410799600.9A patent/CN104530054B/zh active Active
-
2015
- 2015-11-19 KR KR1020177015107A patent/KR102003847B1/ko active IP Right Grant
- 2015-11-19 PL PL15869159.2T patent/PL3216791T3/pl unknown
- 2015-11-19 ES ES15869159T patent/ES2918948T3/es active Active
- 2015-11-19 DK DK15869159.2T patent/DK3216791T3/da active
- 2015-11-19 US US15/535,502 patent/US9884870B2/en active Active
- 2015-11-19 RU RU2017120508A patent/RU2672249C9/ru active
- 2015-11-19 EP EP15869159.2A patent/EP3216791B1/en active Active
- 2015-11-19 PT PT158691592T patent/PT3216791T/pt unknown
- 2015-11-19 CA CA2971484A patent/CA2971484C/en active Active
- 2015-11-19 WO PCT/CN2015/095059 patent/WO2016095650A1/zh active Application Filing
- 2015-11-19 JP JP2017531776A patent/JP6473820B2/ja active Active
Also Published As
Publication number | Publication date |
---|---|
PL3216791T3 (pl) | 2022-09-19 |
ES2918948T3 (es) | 2022-07-21 |
WO2016095650A1 (zh) | 2016-06-23 |
CA2971484C (en) | 2019-08-06 |
RU2672249C1 (ru) | 2018-11-13 |
JP2018503608A (ja) | 2018-02-08 |
JP6473820B2 (ja) | 2019-02-20 |
US20170349592A1 (en) | 2017-12-07 |
CN104530054B (zh) | 2018-01-19 |
EP3216791A4 (en) | 2017-09-13 |
RU2672249C9 (ru) | 2022-03-30 |
KR20170085525A (ko) | 2017-07-24 |
EP3216791B1 (en) | 2022-05-11 |
KR102003847B1 (ko) | 2019-10-01 |
EP3216791A1 (en) | 2017-09-13 |
PT3216791T (pt) | 2022-07-04 |
CN104530054A (zh) | 2015-04-22 |
CA2971484A1 (en) | 2016-06-23 |
US9884870B2 (en) | 2018-02-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK3346961T3 (da) | Anordning til stomi | |
DK3233360T3 (da) | Modstandssvejsefastgørelsesanordning, indretning og fremgangsmåder til samling af tilsvarende og forskellige materialer | |
DK3538864T3 (da) | Mikrotom | |
DK3888658T3 (da) | Eif4-a-inhiberende forbindelser og fremgangsmåder relateret dertil | |
DK3161124T3 (da) | Endofytter, associerede sammensætninger og fremgangsmåder til anvendelse deraf | |
DK3110988T3 (da) | Metoder til behandling af lithiumholdige materialer | |
DK3227336T3 (da) | Anti-CD79b-antistoffer og fremgangsmåder til anvendelse | |
DK3198035T3 (da) | Fremgangsmåder til forudsigelse af medicinrespons | |
DK3072835T3 (da) | Fremgangsmåde til fremføring | |
DK3224603T3 (da) | Nordning og fremgangsmåde til materialekarakteristik | |
DK3215147T3 (da) | Neurodæmpende norketamin-forbindelser og fremgangsmåder | |
DK3092256T3 (da) | Forbindelser og sammensætninger til immunterapi | |
DK3286311T3 (da) | Fremgangsmåde til behandling af maligniteter | |
DK3294700T3 (da) | Fremgangsmåde til fremstilling af limonen-4-ol | |
DK3940352T3 (da) | Fremgangsmåde til diagnosticering af vægte | |
DK3509893T3 (da) | Fremgangsmåde til roaming | |
DK3204386T3 (da) | Substituerede aminopurinforbindelser, sammensætninger deraf og fremgangsmåder til behandling dermed | |
DK3314010T3 (da) | Fremgangsmåde til detektering af kromosomaberrationer | |
DK3253207T3 (da) | Fremgangsmåde til desinficering af en overflade og sammensætning, der er egnet til anvendelse dertil | |
DK3520591T3 (da) | Fremgangsmåde til spredning af gødningsmidler | |
DK3227483T3 (da) | Elastisk stof og fremgangsmåde til fremstilling | |
DK3529233T3 (da) | Fremgangsmåde til fremstilling af 3-alkylsulfanyl-2-chlor-n-(1-alkyl-1h-tetrazol-5-yl)-4-trifluoromethyl-benzamider | |
DK3269676T3 (da) | Holdeindretning til byrde | |
DK3366832T3 (da) | Indretning til identifikation af stoftype | |
DK3265443T3 (da) | Pyrrolidincarboxamidderivater og fremgangsmåde til fremstilling og anvendelse af samme |