DK3214094T3 - Kanalrhodopsiner til optisk kontrol af celler - Google Patents
Kanalrhodopsiner til optisk kontrol af celler Download PDFInfo
- Publication number
- DK3214094T3 DK3214094T3 DK17165633.3T DK17165633T DK3214094T3 DK 3214094 T3 DK3214094 T3 DK 3214094T3 DK 17165633 T DK17165633 T DK 17165633T DK 3214094 T3 DK3214094 T3 DK 3214094T3
- Authority
- DK
- Denmark
- Prior art keywords
- cells
- optical control
- channel rhodopsins
- rhodopsins
- channel
- Prior art date
Links
- 108010035848 Channelrhodopsins Proteins 0.000 title 1
- 230000003287 optical effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/405—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from algae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0023—Agression treatment or altering
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/062—Photodynamic therapy, i.e. excitation of an agent
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N13/00—Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
- G01N33/48728—Investigating individual cells, e.g. by patch clamp, voltage clamp
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5041—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving analysis of members of signalling pathways
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5058—Neurological cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
- A61N2005/0661—Radiation therapy using light characterised by the wavelength of light used ultraviolet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
- A61N2005/0662—Visible light
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161559076P | 2011-11-12 | 2011-11-12 | |
| EP12808926.5A EP2776455B1 (en) | 2011-11-12 | 2012-11-12 | Channelrhodopsins for optical control of cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3214094T3 true DK3214094T3 (da) | 2020-07-13 |
Family
ID=47470101
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK12808926.5T DK2776455T3 (da) | 2011-11-12 | 2012-11-12 | Kanalrhodopsiner til optisk kontrol af celler |
| DK17165633.3T DK3214094T3 (da) | 2011-11-12 | 2012-11-12 | Kanalrhodopsiner til optisk kontrol af celler |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK12808926.5T DK2776455T3 (da) | 2011-11-12 | 2012-11-12 | Kanalrhodopsiner til optisk kontrol af celler |
Country Status (8)
| Country | Link |
|---|---|
| US (6) | US10472398B2 (da) |
| EP (2) | EP3214094B1 (da) |
| KR (2) | KR102084803B1 (da) |
| DK (2) | DK2776455T3 (da) |
| ES (2) | ES2660114T3 (da) |
| HK (2) | HK1202128A1 (da) |
| PL (1) | PL2776455T3 (da) |
| WO (1) | WO2013071231A1 (da) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10022457B2 (en) * | 2005-08-05 | 2018-07-17 | Gholam A. Peyman | Methods to regulate polarization and enhance function of cells |
| US20130309278A1 (en) * | 2005-08-05 | 2013-11-21 | Gholam A. Peyman | Methods to regulate polarization and enhance function of cells |
| US9962558B2 (en) * | 2005-08-05 | 2018-05-08 | Gholam A. Peyman | Methods to regulate polarization and enhance function of cells |
| ES2660114T3 (es) | 2011-11-12 | 2018-03-20 | Massachusetts Institute Of Technology | Canalrodopsinas para el control óptico de células |
| EP3102290A1 (en) * | 2014-02-07 | 2016-12-14 | Massachusetts Institute Of Technology | Blue light-activated ion channel molecules and uses thereof |
| US10590181B2 (en) | 2014-04-18 | 2020-03-17 | Massachusetts Institute Of Technology | Mutant channelrhodopsins with altered ion selectivity |
| US10882892B2 (en) | 2014-08-05 | 2021-01-05 | Massachusetts Institute Of Technology | Channelrhodopsin variants and uses thereof |
| CA3025975A1 (en) * | 2016-04-29 | 2017-11-02 | Gensight Biologics Sa | Optogenetic visual restoration using chrimson |
| WO2017207761A1 (en) | 2016-06-03 | 2017-12-07 | Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V. | Mutant light-inducible ion channel of chrimson |
| KR20190020702A (ko) | 2016-06-03 | 2019-03-04 | 막스-플랑크-게젤샤프트 츄어 푀르더룽 데어 비쎈샤프텐 에.파우. | 채널로돕신의 돌연변이 광-유도성 이온 채널 |
| JP7083821B2 (ja) | 2016-06-17 | 2022-06-13 | ソルボンヌ・ユニヴェルシテ | 制御された光強度で対象物を照明するための装置および関連する方法 |
| WO2018017831A1 (en) * | 2016-07-21 | 2018-01-25 | Massachusetts Institute Of Technology | Dummy-fluorescent protein fusions and methods of use |
| MX2019002321A (es) | 2016-08-29 | 2019-10-21 | Univ Wayne State | Identificación de mutaciones en variantes de opsina de canal con sensibilidad a la luz mejorada y métodos de uso de estas. |
| WO2018106369A2 (en) | 2016-11-06 | 2018-06-14 | Nanoscope Technologies Llc | Optogenetic modulation by multi-characteristic opsins for vision restoration and other applications thereof |
| EP3422065A1 (en) | 2017-06-28 | 2019-01-02 | Gensight Biologics | Objective, camera and system adapted for optogenetics comprising such objective |
| WO2019137973A1 (en) | 2018-01-11 | 2019-07-18 | Gensight Biologics | Method and device for processing asynchronous signals generated by an event-based light sensor |
| TWI653037B (zh) | 2018-01-11 | 2019-03-11 | 友睦科技股份有限公司 | 可控溫的遠紅外線照射設備 |
| US11858969B2 (en) * | 2018-09-18 | 2024-01-02 | California Institute Of Technology | Engineered light-sensitive proteins |
| EP3693061A1 (en) | 2019-02-05 | 2020-08-12 | Gensight Biologics | Method for controlling an optogenetic device using filtering and associated devices |
| EP3693060A1 (en) | 2019-02-05 | 2020-08-12 | Gensight Biologics | Method for controlling an optogenetic device using a command law for the radiant power of a light source and associated devices |
| EP3733139A1 (en) | 2019-05-02 | 2020-11-04 | Gensight Biologics | Viewing apparatus and method for projecting a light signal |
| US11454402B1 (en) | 2021-12-01 | 2022-09-27 | Mcevoy William B | Tabletop cooking assembly |
| EP4223768A1 (en) | 2022-02-04 | 2023-08-09 | Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin | Novel mutant bacteriorhodopsin-like-channelrhodopsin ion channel |
| WO2024015705A1 (en) * | 2022-07-09 | 2024-01-18 | Bionic Sight, Llc | An optogenetic gene therapy for treating blindness |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1322439C (en) | 1988-03-28 | 1993-09-28 | Junji Ohyama | Ion permeable membrane and ion transport method by utilizing said membrane |
| US6197387B1 (en) | 1996-10-25 | 2001-03-06 | Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E. V. | Method to prepare the production of structured metal coatings using proteins |
| WO2002010207A2 (de) | 2000-07-27 | 2002-02-07 | Mib Munich Innovative Biomaterials Gmbh | Protonen-translozierendes retinalprotein |
| DE10216005A1 (de) | 2002-04-11 | 2003-10-30 | Max Planck Gesellschaft | Verwendung von biologischen Photorezeptoren als direkt lichtgesteuerte Ionenkanäle |
| US9274099B2 (en) | 2005-07-22 | 2016-03-01 | The Board Of Trustees Of The Leland Stanford Junior University | Screening test drugs to identify their effects on cell membrane voltage-gated ion channel |
| US8906360B2 (en) | 2005-07-22 | 2014-12-09 | The Board Of Trustees Of The Leland Stanford Junior University | Light-activated cation channel and uses thereof |
| CN101484005A (zh) * | 2006-05-04 | 2009-07-15 | 韦恩州立大学 | 通过向体内递送视紫红质核酸恢复视觉响应 |
| WO2008086470A1 (en) | 2007-01-10 | 2008-07-17 | The Board Of Trustees Of The Leland Stanford Junior University | System for optical stimulation of target cells |
| US8401609B2 (en) | 2007-02-14 | 2013-03-19 | The Board Of Trustees Of The Leland Stanford Junior University | System, method and applications involving identification of biological circuits such as neurological characteristics |
| US20110165681A1 (en) | 2009-02-26 | 2011-07-07 | Massachusetts Institute Of Technology | Light-Activated Proton Pumps and Applications Thereof |
| US9138596B2 (en) * | 2007-08-22 | 2015-09-22 | Cardiac Pacemakers, Inc. | Optical depolarization of cardiac tissue |
| JP5544659B2 (ja) * | 2008-03-24 | 2014-07-09 | 国立大学法人東北大学 | 改変された光受容体チャネル型ロドプシンタンパク質 |
| KR20100136550A (ko) * | 2008-04-18 | 2010-12-28 | 노파르티스 포르슝스티프퉁 쯔바이크니덜라쑹 프리드리히 미셔 인스티튜트 포 바이오메디칼 리서치 | 실명을 치료하기 위한 신규의 치료 도구 및 방법 |
| DE102008020152B4 (de) * | 2008-04-22 | 2012-04-05 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Verwendung von biologischen Photorezeptoren als direkt lichtgesteuerte Ionenkanäle |
| ES2608498T3 (es) * | 2008-04-23 | 2017-04-11 | The Board Of Trustees Of The Leland Stanford Junior University | Sistemas, métodos y composiciones para la estimulación óptica de células diana |
| WO2010033230A2 (en) | 2008-09-18 | 2010-03-25 | Shai Einbinder | Use of fluorescent protien in cyanobacteria and algae for improving photosynthesis and preventing cell damage |
| NZ602416A (en) | 2008-11-14 | 2014-08-29 | Univ Leland Stanford Junior | Optically-based stimulation of target cells and modifications thereto |
| EP2635108B1 (en) * | 2010-11-05 | 2019-01-23 | The Board of Trustees of the Leland Stanford Junior University | Light-activated chimeric opsins and methods of using the same |
| EP2635111B1 (en) | 2010-11-05 | 2018-05-23 | The Board of Trustees of the Leland Stanford Junior University | Stabilized step function opsin proteins and methods of using the same |
| US20120214188A1 (en) | 2010-11-12 | 2012-08-23 | Nathan Klapoetke | Light-activated ion channel molecules and uses thereof |
| US8957028B2 (en) | 2010-11-13 | 2015-02-17 | Massachusetts Institute Of Technology | Red-shifted opsin molecules and uses thereof |
| ES2660114T3 (es) | 2011-11-12 | 2018-03-20 | Massachusetts Institute Of Technology | Canalrodopsinas para el control óptico de células |
-
2012
- 2012-11-12 ES ES12808926.5T patent/ES2660114T3/es active Active
- 2012-11-12 WO PCT/US2012/064665 patent/WO2013071231A1/en active Application Filing
- 2012-11-12 DK DK12808926.5T patent/DK2776455T3/da active
- 2012-11-12 US US14/357,635 patent/US10472398B2/en active Active
- 2012-11-12 KR KR1020147015784A patent/KR102084803B1/ko active IP Right Grant
- 2012-11-12 EP EP17165633.3A patent/EP3214094B1/en active Active
- 2012-11-12 DK DK17165633.3T patent/DK3214094T3/da active
- 2012-11-12 EP EP12808926.5A patent/EP2776455B1/en active Active
- 2012-11-12 ES ES17165633T patent/ES2801679T3/es active Active
- 2012-11-12 KR KR1020207005571A patent/KR102194185B1/ko active IP Right Grant
- 2012-11-12 PL PL12808926T patent/PL2776455T3/pl unknown
-
2015
- 2015-03-16 HK HK15102671.5A patent/HK1202128A1/xx unknown
-
2016
- 2016-11-23 US US15/359,875 patent/US10472399B2/en active Active
-
2018
- 2018-03-05 HK HK18103122.5A patent/HK1243717A1/zh unknown
-
2019
- 2019-08-02 US US16/530,047 patent/US10717769B2/en active Active
- 2019-09-13 US US16/570,429 patent/US10711044B2/en active Active
-
2020
- 2020-05-28 US US16/885,457 patent/US11274128B2/en active Active
-
2022
- 2022-02-10 US US17/668,766 patent/US20220169684A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20200291074A1 (en) | 2020-09-17 |
| DK2776455T3 (da) | 2018-02-26 |
| US20190352347A1 (en) | 2019-11-21 |
| US20170088590A1 (en) | 2017-03-30 |
| ES2801679T3 (es) | 2021-01-12 |
| US10717769B2 (en) | 2020-07-21 |
| PL2776455T3 (pl) | 2018-07-31 |
| US10472398B2 (en) | 2019-11-12 |
| US20200031883A1 (en) | 2020-01-30 |
| ES2660114T3 (es) | 2018-03-20 |
| US20140324134A1 (en) | 2014-10-30 |
| WO2013071231A1 (en) | 2013-05-16 |
| US10472399B2 (en) | 2019-11-12 |
| EP3214094B1 (en) | 2020-04-01 |
| US11274128B2 (en) | 2022-03-15 |
| KR20140091743A (ko) | 2014-07-22 |
| EP2776455A1 (en) | 2014-09-17 |
| EP2776455B1 (en) | 2018-01-10 |
| HK1202128A1 (en) | 2015-09-18 |
| HK1243717A1 (zh) | 2018-07-20 |
| US20220169684A1 (en) | 2022-06-02 |
| KR20200024336A (ko) | 2020-03-06 |
| US10711044B2 (en) | 2020-07-14 |
| KR102194185B1 (ko) | 2020-12-22 |
| EP3214094A1 (en) | 2017-09-06 |
| KR102084803B1 (ko) | 2020-03-05 |
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