DK320680A - Fremgangsmaade til fremstilling af fluorerede beta-alanin-derivater - Google Patents

Fremgangsmaade til fremstilling af fluorerede beta-alanin-derivater

Info

Publication number
DK320680A
DK320680A DK320680A DK320680A DK320680A DK 320680 A DK320680 A DK 320680A DK 320680 A DK320680 A DK 320680A DK 320680 A DK320680 A DK 320680A DK 320680 A DK320680 A DK 320680A
Authority
DK
Denmark
Prior art keywords
fluored
beta
procedure
preparation
alanine derivatives
Prior art date
Application number
DK320680A
Other languages
English (en)
Other versions
DK149269C (da
DK149269B (da
Inventor
P Bey
M Jung
F Gerhart
Original Assignee
Merrell Toraude & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Toraude & Co filed Critical Merrell Toraude & Co
Publication of DK320680A publication Critical patent/DK320680A/da
Publication of DK149269B publication Critical patent/DK149269B/da
Application granted granted Critical
Publication of DK149269C publication Critical patent/DK149269C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/20Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04Formation of amino groups in compounds containing carboxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK320680A 1979-07-26 1980-07-24 Analogifremgangsmaade til fremstilling af beta-mono- eller -difluormethyl-beta-alanin-derivater eller farmaceutisk acceptable salte eller optiske isomere deraf DK149269C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB7926030 1979-07-26
GB7926030 1979-07-26
GB8002553 1980-01-25
GB8002553 1980-01-25

Publications (3)

Publication Number Publication Date
DK320680A true DK320680A (da) 1981-01-27
DK149269B DK149269B (da) 1986-04-14
DK149269C DK149269C (da) 1986-08-25

Family

ID=26272327

Family Applications (1)

Application Number Title Priority Date Filing Date
DK320680A DK149269C (da) 1979-07-26 1980-07-24 Analogifremgangsmaade til fremstilling af beta-mono- eller -difluormethyl-beta-alanin-derivater eller farmaceutisk acceptable salte eller optiske isomere deraf

Country Status (10)

Country Link
US (1) US4375477A (da)
EP (1) EP0024965B1 (da)
AU (1) AU536371B2 (da)
CA (1) CA1161450A (da)
DE (1) DE3062893D1 (da)
DK (1) DK149269C (da)
ES (1) ES8105969A1 (da)
NO (1) NO151319C (da)
NZ (1) NZ194348A (da)
PH (1) PH16349A (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1158657A (en) * 1979-07-26 1983-12-13 Philippe Bey Preparation of fluorinated methyl aminoalkanoic acids and novel process intermediates
GB2082578B (en) * 1980-08-23 1984-05-23 Merrell Toraude & Co Fluorinated amino-butyric acid and diaminobutane derivatives
GB2083030B (en) * 1980-08-23 1984-03-07 Merrell Toraude & Co Fluorinated pentene diamine derivatives
US4518528A (en) * 1983-05-19 1985-05-21 Rasnick David W α Amino fluoro ketones
EP0353732A3 (de) * 1988-08-05 1991-11-06 Ciba-Geigy Ag Neue Fluorolefine, Verfahren zu deren Herstellung und deren Verwendung
US6001876A (en) 1996-07-24 1999-12-14 Warner-Lambert Company Isobutylgaba and its derivatives for the treatment of pain
US6306909B1 (en) * 1997-03-12 2001-10-23 Queen's University At Kingston Anti-epileptogenic agents
US6541520B1 (en) * 1998-08-05 2003-04-01 Brookhaven Science Associates Treatment of addiction and addiction-related behavior
IL157845A0 (en) * 2001-03-13 2004-03-28 Univ Kingston Anti-epileptogenic agents
US20030032579A1 (en) * 2001-04-20 2003-02-13 Pfizer Inc. Therapeutic use of selective PDE10 inhibitors
WO2002096424A1 (en) * 2001-05-25 2002-12-05 Queen's University At Kingston Hetereocyclic beta-aminoacids and their use as anti-epileptogenic agents
WO2003102015A2 (en) * 2002-05-29 2003-12-11 University Of Florida Method and apparatus for detecting and monitoring peptides, and peptides identified therewith
AU2014209028C1 (en) 2013-01-28 2019-08-29 Hector L. Lopez Methods of improving tolerability, pharmacodynamics, and efficacy of b-alanine and use therefor

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2662915A (en) * 1952-06-30 1953-12-15 Du Pont Alpha-amino acids containing alpha, fluorinated-alkyl or cycloalkyl groups
JPS5225458Y2 (da) * 1971-05-17 1977-06-10
SE7511733L (sv) * 1974-11-08 1976-05-10 Merck & Co Inc Syntes av recemisk 3-fluoro-alanin och salter derav, samt mellanprodukt i denna syntes
US3972921A (en) * 1974-11-08 1976-08-03 Merck & Co., Inc. Synthesis of racemic 2-deutero-3-fluoro-alanine and its salts
IE46910B1 (en) * 1977-06-01 1983-11-02 Merck & Co Inc Fluorinated alkylamines and process for preparing same
IE47542B1 (en) * 1977-06-01 1984-04-18 Merck & Co Inc Di-and tri-fluoromethyl amino acids and amines,compositions and processes for preparing said compounds
US4326071A (en) 1977-09-28 1982-04-20 Merrell Toraude Et Compagnie Halomethyl derivatives of gamma-aminobutyric acid and related compounds
US4264590A (en) * 1979-05-23 1981-04-28 Abbott Laboratories Antibacterial peptide

Also Published As

Publication number Publication date
ES493555A0 (es) 1981-07-01
DK149269C (da) 1986-08-25
AU6047680A (en) 1981-02-05
AU536371B2 (en) 1984-05-03
US4375477A (en) 1983-03-01
PH16349A (en) 1983-09-05
EP0024965A1 (en) 1981-03-11
NZ194348A (en) 1982-09-14
ES8105969A1 (es) 1981-07-01
DK149269B (da) 1986-04-14
CA1161450A (en) 1984-01-31
EP0024965B1 (en) 1983-04-27
NO151319B (no) 1984-12-10
NO802218L (no) 1981-01-27
DE3062893D1 (en) 1983-06-01
NO151319C (no) 1985-03-20

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Legal Events

Date Code Title Description
PBP Patent lapsed