DK3193945T3 - Upar-målrettende peptid til anvendelse ved peroperativ optisk billeddannelse af invasiv cancer - Google Patents
Upar-målrettende peptid til anvendelse ved peroperativ optisk billeddannelse af invasiv cancer Download PDFInfo
- Publication number
- DK3193945T3 DK3193945T3 DK15842107.3T DK15842107T DK3193945T3 DK 3193945 T3 DK3193945 T3 DK 3193945T3 DK 15842107 T DK15842107 T DK 15842107T DK 3193945 T3 DK3193945 T3 DK 3193945T3
- Authority
- DK
- Denmark
- Prior art keywords
- peptime
- optical imaging
- invasive cancer
- peroperative
- upar targeted
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 101150038998 PLAUR gene Proteins 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 238000012634 optical imaging Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
- A61K49/0056—Peptides, proteins, polyamino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
- A61K49/0032—Methine dyes, e.g. cyanine dyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
- A61K49/0032—Methine dyes, e.g. cyanine dyes
- A61K49/0034—Indocyanine green, i.e. ICG, cardiogreen
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA201470573 | 2014-09-17 | ||
| PCT/DK2015/050261 WO2016041558A1 (en) | 2014-09-17 | 2015-09-03 | Upar targeting peptide for use in peroperative optical imaging of invasive cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3193945T3 true DK3193945T3 (da) | 2020-11-16 |
Family
ID=59093318
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15842107.3T DK3193945T3 (da) | 2014-09-17 | 2015-09-03 | Upar-målrettende peptid til anvendelse ved peroperativ optisk billeddannelse af invasiv cancer |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US10111969B2 (da) |
| EP (2) | EP3733215A1 (da) |
| AU (1) | AU2015317444B2 (da) |
| CA (1) | CA2961095C (da) |
| DK (1) | DK3193945T3 (da) |
| ES (1) | ES2828954T3 (da) |
| PT (1) | PT3193945T (da) |
| WO (1) | WO2016041558A1 (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2905172C (en) * | 2012-05-08 | 2021-07-20 | Andreas Kjaer | 177-lu labeled peptide for site-specific upar-targeting |
| EP2928505B1 (en) * | 2012-12-03 | 2019-08-28 | Curasight APS | Positron emitting radionuclide labeled peptides for human upar pet imaging |
| WO2016041558A1 (en) * | 2014-09-17 | 2016-03-24 | Rigshospitalet | Upar targeting peptide for use in peroperative optical imaging of invasive cancer |
| WO2019113248A1 (en) * | 2017-12-07 | 2019-06-13 | The Regents Of The University Of California | Anti-upar antibody-drug conjugates and methods of use thereof |
| US20220257799A1 (en) | 2019-07-16 | 2022-08-18 | Fluoguide A/S | A receptor-targeting conjugate with an effective pharmacokinetic profile |
| AU2020314065A1 (en) | 2019-07-16 | 2022-02-17 | Fluoguide A/S | A urokinase plasminogen activator receptor-targeting peptide |
| EP3842073A1 (en) | 2019-12-23 | 2021-06-30 | Rigshospitalet | Upar-targeted photothermal optical probes for photothermal therapy |
| EP4090385A1 (en) * | 2020-01-17 | 2022-11-23 | Fluoguide A/S | A composition comprising a fluorophore labelled upar-targeting peptide conjugate |
| US20240066142A1 (en) | 2021-01-15 | 2024-02-29 | Fluoguide A/S | A upar (urokinase plasminogen activator receptor)-targeting conjugate |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2211470A1 (en) * | 1995-01-30 | 1996-08-08 | Daiichi Pure Chemicals Co., Ltd. | Diagnostic marker |
| GB9708265D0 (en) * | 1997-04-24 | 1997-06-18 | Nycomed Imaging As | Contrast agents |
| US20040204348A1 (en) | 1996-11-12 | 2004-10-14 | The Angstrom Pharmaceuticals, Inc. | Cyclic peptide ligands that target urokinase plasminogen activator receptor |
| AR020101A1 (es) | 1998-07-01 | 2002-04-10 | Cancerforskingsfonden Af 1989 | Un antagonista peptido del receptor de uroquinasa humana, composicion farmaceutica que lo contiene, su uso para la manufactura de un medicamento y metodopara seleccionar un antagonista peptido adecuado. |
| NO20035683D0 (no) | 2003-12-18 | 2003-12-18 | Amersham Health As | Optisk avbildning av prostatakreft |
| NO20035681D0 (no) * | 2003-12-18 | 2003-12-18 | Amersham Health As | Optisk avbildning av lungekreft |
| AU2005287934B2 (en) * | 2004-09-29 | 2009-03-26 | Ge Healthcare As | Urokinase plasminogen activator receptor targeted contrast agent |
| WO2013029616A1 (en) * | 2011-08-31 | 2013-03-07 | Rigshospitalet | Pet tracer for imaging of neuroendocrine tumors |
| CA2905172C (en) | 2012-05-08 | 2021-07-20 | Andreas Kjaer | 177-lu labeled peptide for site-specific upar-targeting |
| EP2928505B1 (en) * | 2012-12-03 | 2019-08-28 | Curasight APS | Positron emitting radionuclide labeled peptides for human upar pet imaging |
| WO2016041558A1 (en) * | 2014-09-17 | 2016-03-24 | Rigshospitalet | Upar targeting peptide for use in peroperative optical imaging of invasive cancer |
-
2015
- 2015-09-03 WO PCT/DK2015/050261 patent/WO2016041558A1/en active Application Filing
- 2015-09-03 DK DK15842107.3T patent/DK3193945T3/da active
- 2015-09-03 AU AU2015317444A patent/AU2015317444B2/en active Active
- 2015-09-03 PT PT158421073T patent/PT3193945T/pt unknown
- 2015-09-03 ES ES15842107T patent/ES2828954T3/es active Active
- 2015-09-03 CA CA2961095A patent/CA2961095C/en active Active
- 2015-09-03 EP EP20174184.0A patent/EP3733215A1/en active Pending
- 2015-09-03 US US15/512,276 patent/US10111969B2/en active Active
- 2015-09-03 EP EP15842107.3A patent/EP3193945B1/en active Active
-
2018
- 2018-09-26 US US16/142,977 patent/US20190125903A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US10111969B2 (en) | 2018-10-30 |
| CA2961095A1 (en) | 2016-03-24 |
| US20190125903A1 (en) | 2019-05-02 |
| EP3733215A1 (en) | 2020-11-04 |
| EP3193945A4 (en) | 2018-05-16 |
| EP3193945A1 (en) | 2017-07-26 |
| PT3193945T (pt) | 2020-10-27 |
| US20170304468A1 (en) | 2017-10-26 |
| EP3193945B1 (en) | 2020-08-19 |
| AU2015317444A1 (en) | 2017-04-06 |
| WO2016041558A1 (en) | 2016-03-24 |
| AU2015317444B2 (en) | 2020-07-16 |
| CA2961095C (en) | 2021-02-09 |
| ES2828954T3 (es) | 2021-05-28 |
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