DK3193945T3 - Upar-målrettende peptid til anvendelse ved peroperativ optisk billeddannelse af invasiv cancer - Google Patents

Upar-målrettende peptid til anvendelse ved peroperativ optisk billeddannelse af invasiv cancer Download PDF

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Publication number
DK3193945T3
DK3193945T3 DK15842107.3T DK15842107T DK3193945T3 DK 3193945 T3 DK3193945 T3 DK 3193945T3 DK 15842107 T DK15842107 T DK 15842107T DK 3193945 T3 DK3193945 T3 DK 3193945T3
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DK
Denmark
Prior art keywords
peptime
optical imaging
invasive cancer
peroperative
upar targeted
Prior art date
Application number
DK15842107.3T
Other languages
English (en)
Inventor
Morten Persson
Andreas Kjaer
Original Assignee
Fluoguide As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fluoguide As filed Critical Fluoguide As
Application granted granted Critical
Publication of DK3193945T3 publication Critical patent/DK3193945T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0056—Peptides, proteins, polyamino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032—Methine dyes, e.g. cyanine dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032—Methine dyes, e.g. cyanine dyes
    • A61K49/0034—Indocyanine green, i.e. ICG, cardiogreen

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
DK15842107.3T 2014-09-17 2015-09-03 Upar-målrettende peptid til anvendelse ved peroperativ optisk billeddannelse af invasiv cancer DK3193945T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA201470573 2014-09-17
PCT/DK2015/050261 WO2016041558A1 (en) 2014-09-17 2015-09-03 Upar targeting peptide for use in peroperative optical imaging of invasive cancer

Publications (1)

Publication Number Publication Date
DK3193945T3 true DK3193945T3 (da) 2020-11-16

Family

ID=59093318

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15842107.3T DK3193945T3 (da) 2014-09-17 2015-09-03 Upar-målrettende peptid til anvendelse ved peroperativ optisk billeddannelse af invasiv cancer

Country Status (8)

Country Link
US (2) US10111969B2 (da)
EP (2) EP3193945B1 (da)
AU (1) AU2015317444B2 (da)
CA (1) CA2961095C (da)
DK (1) DK3193945T3 (da)
ES (1) ES2828954T3 (da)
PT (1) PT3193945T (da)
WO (1) WO2016041558A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104768573B (zh) * 2012-05-08 2017-08-29 Trt创新有限责任公司 用于位点特异性uPAR靶向的177‑Lu标记肽
DK2928505T3 (da) * 2012-12-03 2019-11-25 Curasight Aps Positron-emitterende radionuklidmærkede peptider til human upar-pet-billeddannelse
PT3193945T (pt) * 2014-09-17 2020-10-27 Fluoguide As Péptido direcionado a upar para utilização em imagiologia ótica peroperatória em cancro invasivo
WO2019113248A1 (en) * 2017-12-07 2019-06-13 The Regents Of The University Of California Anti-upar antibody-drug conjugates and methods of use thereof
EP3999123A1 (en) 2019-07-16 2022-05-25 Fluoguide A/S A receptor-targeting conjugate with an effective pharmacokinetic profile
EP3999094A1 (en) 2019-07-16 2022-05-25 Rigshospitalet A urokinase plasminogen activator receptor-targeting peptide
EP3842073A1 (en) 2019-12-23 2021-06-30 Rigshospitalet Upar-targeted photothermal optical probes for photothermal therapy
CN115379864A (zh) * 2020-01-17 2022-11-22 荧光向导股份公司 包含荧光团标记的uPAR靶向肽缀合物的组合物
US20240066142A1 (en) 2021-01-15 2024-02-29 Fluoguide A/S A upar (urokinase plasminogen activator receptor)-targeting conjugate

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1093768C (zh) * 1995-01-30 2002-11-06 第一化学药品株式会社 诊断用标记物
GB9708265D0 (en) 1997-04-24 1997-06-18 Nycomed Imaging As Contrast agents
US20040204348A1 (en) * 1996-11-12 2004-10-14 The Angstrom Pharmaceuticals, Inc. Cyclic peptide ligands that target urokinase plasminogen activator receptor
AR020101A1 (es) 1998-07-01 2002-04-10 Cancerforskingsfonden Af 1989 Un antagonista peptido del receptor de uroquinasa humana, composicion farmaceutica que lo contiene, su uso para la manufactura de un medicamento y metodopara seleccionar un antagonista peptido adecuado.
NO20035683D0 (no) 2003-12-18 2003-12-18 Amersham Health As Optisk avbildning av prostatakreft
NO20035681D0 (no) * 2003-12-18 2003-12-18 Amersham Health As Optisk avbildning av lungekreft
US8568689B1 (en) * 2004-09-29 2013-10-29 Ge Healthcare As uPAR-targeting contrast agents
EP3536346B1 (en) * 2011-08-31 2020-10-28 Somscan ApS Pet tracer for imaging of neuroendocrine tumors
CN104768573B (zh) * 2012-05-08 2017-08-29 Trt创新有限责任公司 用于位点特异性uPAR靶向的177‑Lu标记肽
DK2928505T3 (da) * 2012-12-03 2019-11-25 Curasight Aps Positron-emitterende radionuklidmærkede peptider til human upar-pet-billeddannelse
PT3193945T (pt) * 2014-09-17 2020-10-27 Fluoguide As Péptido direcionado a upar para utilização em imagiologia ótica peroperatória em cancro invasivo

Also Published As

Publication number Publication date
PT3193945T (pt) 2020-10-27
AU2015317444B2 (en) 2020-07-16
ES2828954T3 (es) 2021-05-28
EP3193945A1 (en) 2017-07-26
WO2016041558A1 (en) 2016-03-24
EP3193945A4 (en) 2018-05-16
CA2961095A1 (en) 2016-03-24
US10111969B2 (en) 2018-10-30
AU2015317444A1 (en) 2017-04-06
CA2961095C (en) 2021-02-09
EP3733215A1 (en) 2020-11-04
US20190125903A1 (en) 2019-05-02
US20170304468A1 (en) 2017-10-26
EP3193945B1 (en) 2020-08-19

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