DK2928505T3 - Positron-emitterende radionuklidmærkede peptider til human upar-pet-billeddannelse - Google Patents

Positron-emitterende radionuklidmærkede peptider til human upar-pet-billeddannelse Download PDF

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Publication number
DK2928505T3
DK2928505T3 DK13860317T DK13860317T DK2928505T3 DK 2928505 T3 DK2928505 T3 DK 2928505T3 DK 13860317 T DK13860317 T DK 13860317T DK 13860317 T DK13860317 T DK 13860317T DK 2928505 T3 DK2928505 T3 DK 2928505T3
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DK
Denmark
Prior art keywords
imagination
positron
pet
labeled peptides
emitting radionuclide
Prior art date
Application number
DK13860317T
Other languages
English (en)
Inventor
Morten Persson
Jacob Madsen
Andreas Kjaer
Original Assignee
Curasight Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Curasight Aps filed Critical Curasight Aps
Application granted granted Critical
Publication of DK2928505T3 publication Critical patent/DK2928505T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/083Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK13860317T 2012-12-03 2013-11-29 Positron-emitterende radionuklidmærkede peptider til human upar-pet-billeddannelse DK2928505T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA201270751 2012-12-03
PCT/DK2013/050402 WO2014086364A1 (en) 2012-12-03 2013-11-29 Positron emitting radionuclide labeled peptides for human upar pet imaging

Publications (1)

Publication Number Publication Date
DK2928505T3 true DK2928505T3 (da) 2019-11-25

Family

ID=50882823

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13860317T DK2928505T3 (da) 2012-12-03 2013-11-29 Positron-emitterende radionuklidmærkede peptider til human upar-pet-billeddannelse

Country Status (8)

Country Link
US (4) US9884131B2 (da)
EP (2) EP2928505B1 (da)
CA (3) CA2903261C (da)
DK (1) DK2928505T3 (da)
ES (2) ES2972124T3 (da)
HU (1) HUE046326T2 (da)
PL (2) PL3590542T3 (da)
WO (1) WO2014086364A1 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2905172C (en) * 2012-05-08 2021-07-20 Andreas Kjaer 177-lu labeled peptide for site-specific upar-targeting
ES2972124T3 (es) * 2012-12-03 2024-06-11 Curasight As Péptidos marcados con un radionúclido que emite positrones para obtención de imágenes de PET del uPAR humana
CN104725473B (zh) * 2014-09-11 2018-03-20 厦门大学附属第一医院 一种[18F]AlF标记的PET多肽探针及其制备方法
EP3733215A1 (en) 2014-09-17 2020-11-04 Fluoguide A/S Upar targeting peptide for use in peroperative optical imaging of invasive cancer
AU2015353573B2 (en) 2014-11-25 2020-09-03 Bristol-Myers Squibb Company Novel PD-L1 binding polypeptides for imaging
US11229713B2 (en) 2014-11-25 2022-01-25 Bristol-Myers Squibb Company Methods and compositions for 18F-radiolabeling of biologics
US11344639B2 (en) 2016-06-01 2022-05-31 Bristol-Myers Squibb Company PET imaging with PD-L1 binding polypeptides
US10994033B2 (en) 2016-06-01 2021-05-04 Bristol-Myers Squibb Company Imaging methods using 18F-radiolabeled biologics
US11987629B2 (en) 2018-06-01 2024-05-21 Tayu Huaxia Biotech Medical Group Co., Ltd. Compositions and uses thereof for treating disease or condition
CN109285142B (zh) * 2018-08-07 2023-01-06 广州智能装备研究院有限公司 一种头颈部肿瘤检测方法、装置及计算机可读存储介质
WO2023099472A1 (en) 2021-11-30 2023-06-08 Curasight A/S Urokinase-type plasminogen activator receptor (upar)-pet/ct in head and neck squamous cell carcinomas (hnsccs)
EP4197561A1 (en) 2021-12-15 2023-06-21 Curasight A/S Urokinase-type plasminogen activator receptor (upar)-pet/ct in neuroendocrine neoplams

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1991395A (en) 1994-03-11 1995-10-03 Wilson Greatbatch Ltd. Low power electromagnetic pump
US6277818B1 (en) 1998-10-29 2001-08-21 Angstrom Pharmaceuticals, Inc. Cyclic peptide ligands that target urokinase plasminogen activator receptor
US5942492A (en) 1996-11-12 1999-08-24 Angstrom Pharmaceuticals, Inc. Cyclic peptides that bind to urokinase-type plasminogen activator receptor
AR020101A1 (es) 1998-07-01 2002-04-10 Cancerforskingsfonden Af 1989 Un antagonista peptido del receptor de uroquinasa humana, composicion farmaceutica que lo contiene, su uso para la manufactura de un medicamento y metodopara seleccionar un antagonista peptido adecuado.
EP1218496A2 (en) 1999-10-01 2002-07-03 Angstrom Pharmaceuticals, inc. DIAGNOSTIC PROBES AND THERAPEUTICS TARGETING uPA AND uPAR
US6896870B1 (en) * 1999-10-01 2005-05-24 Angstrom Pharmaceuticals, Inc. Diagnostic probes and therapeutics targeting uPA and uPAR
KR101248350B1 (ko) * 2004-09-29 2013-04-01 지이 헬스케어 에이에스 uPAR 영상화제
US20100233082A1 (en) * 2006-08-28 2010-09-16 Bengt Langstrom 68GA-Labeled Peptide-Based Radiopharmaceuticals
US10159759B2 (en) * 2011-08-31 2018-12-25 Somscan Aps Pet tracer for imaging of neuroendocrine tumors
CN102600489A (zh) * 2012-02-24 2012-07-25 南方医科大学南方医院 含iRGD序列的多肽放射性药物
CA2905172C (en) * 2012-05-08 2021-07-20 Andreas Kjaer 177-lu labeled peptide for site-specific upar-targeting
ES2972124T3 (es) * 2012-12-03 2024-06-11 Curasight As Péptidos marcados con un radionúclido que emite positrones para obtención de imágenes de PET del uPAR humana
EP3733215A1 (en) * 2014-09-17 2020-11-04 Fluoguide A/S Upar targeting peptide for use in peroperative optical imaging of invasive cancer

Also Published As

Publication number Publication date
EP3590542B1 (en) 2024-01-03
PL3590542T3 (pl) 2024-05-13
EP2928505B1 (en) 2019-08-28
EP3590542C0 (en) 2024-01-03
PL2928505T3 (pl) 2020-02-28
US9884131B2 (en) 2018-02-06
EP2928505A4 (en) 2016-08-24
US20220202966A1 (en) 2022-06-30
ES2972124T3 (es) 2024-06-11
ES2755804T3 (es) 2020-04-23
CA3221851A1 (en) 2014-06-12
CA2903261A1 (en) 2014-06-12
CA2903261C (en) 2021-03-09
EP3590542A1 (en) 2020-01-08
EP2928505A1 (en) 2015-10-14
CA3106713A1 (en) 2014-06-12
HUE046326T2 (hu) 2020-03-30
US11311637B2 (en) 2022-04-26
CA3106713C (en) 2024-01-09
WO2014086364A1 (en) 2014-06-12
US20160263260A1 (en) 2016-09-15
US20200268914A1 (en) 2020-08-27
US20180193495A1 (en) 2018-07-12

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