DK3169334T3 - Rna til anvendelse til behandling af ledbånds- eller senelæsioner - Google Patents
Rna til anvendelse til behandling af ledbånds- eller senelæsioner Download PDFInfo
- Publication number
- DK3169334T3 DK3169334T3 DK15747397.6T DK15747397T DK3169334T3 DK 3169334 T3 DK3169334 T3 DK 3169334T3 DK 15747397 T DK15747397 T DK 15747397T DK 3169334 T3 DK3169334 T3 DK 3169334T3
- Authority
- DK
- Denmark
- Prior art keywords
- tense
- injuries
- rna
- link
- treatment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
- A61K48/0016—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the nucleic acid is delivered as a 'naked' nucleic acid, i.e. not combined with an entity such as a cationic lipid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
- A61K48/0066—Manipulation of the nucleic acid to modify its expression pattern, e.g. enhance its duration of expression, achieved by the presence of particular introns in the delivered nucleic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0075—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the delivery route, e.g. oral, subcutaneous
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14177302 | 2014-07-16 | ||
| PCT/EP2015/066329 WO2016009000A1 (en) | 2014-07-16 | 2015-07-16 | Rna for use in the treatment of ligament or tendon lesions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3169334T3 true DK3169334T3 (da) | 2021-07-05 |
Family
ID=51178781
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15747397.6T DK3169334T3 (da) | 2014-07-16 | 2015-07-16 | Rna til anvendelse til behandling af ledbånds- eller senelæsioner |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US10272161B2 (da) |
| EP (1) | EP3169334B1 (da) |
| DK (1) | DK3169334T3 (da) |
| ES (1) | ES2879606T3 (da) |
| WO (1) | WO2016009000A1 (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TR201910686T4 (tr) | 2011-06-08 | 2019-08-21 | Translate Bio Inc | Mrna iletimine yönelik lipit nanopartikül bileşimleri ve yöntemler. |
| DK3169334T3 (da) * | 2014-07-16 | 2021-07-05 | Ethris Gmbh | Rna til anvendelse til behandling af ledbånds- eller senelæsioner |
| US10335498B2 (en) | 2014-12-29 | 2019-07-02 | University Of Iowa Research Foundation | RNA based biomaterial for tissue engineering applications |
| AU2017368050A1 (en) | 2016-11-29 | 2019-06-20 | Puretech Lyt, Inc. | Exosomes for delivery of therapeutic agents |
| US11904006B2 (en) | 2019-12-11 | 2024-02-20 | University Of Iowa Research Foundation | Poly(diaminosulfide) particle-based vaccine |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7105481B2 (en) * | 1998-11-10 | 2006-09-12 | Ludwig Institute For Cancer Research | Method for stimulating connective tissue growth or wound healing |
| DE102005023170A1 (de) | 2005-05-19 | 2006-11-23 | Curevac Gmbh | Optimierte Formulierung für mRNA |
| AU2007223383A1 (en) * | 2006-03-03 | 2007-09-13 | Wyeth | Treatment of tendinopathy by inhibition of molecules that contribute to cartilage formation |
| CN102695525B (zh) | 2009-07-31 | 2016-01-20 | 埃泽瑞斯公司 | 用于蛋白质表达的具有未修饰和修饰核苷酸的组合的rna |
| DK3169334T3 (da) * | 2014-07-16 | 2021-07-05 | Ethris Gmbh | Rna til anvendelse til behandling af ledbånds- eller senelæsioner |
-
2015
- 2015-07-16 DK DK15747397.6T patent/DK3169334T3/da active
- 2015-07-16 ES ES15747397T patent/ES2879606T3/es active Active
- 2015-07-16 EP EP15747397.6A patent/EP3169334B1/en active Active
- 2015-07-16 WO PCT/EP2015/066329 patent/WO2016009000A1/en active Application Filing
- 2015-07-16 US US15/326,332 patent/US10272161B2/en active Active
-
2019
- 2019-04-29 US US16/398,191 patent/US11065346B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2016009000A1 (en) | 2016-01-21 |
| ES2879606T3 (es) | 2021-11-22 |
| US11065346B2 (en) | 2021-07-20 |
| US20170189552A1 (en) | 2017-07-06 |
| EP3169334B1 (en) | 2021-04-28 |
| US20190381193A1 (en) | 2019-12-19 |
| EP3169334A1 (en) | 2017-05-24 |
| US10272161B2 (en) | 2019-04-30 |
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