DK314280A - Fremgangsmaade til fremstilling af thienamycin og mellemprodukter til brug ved udoevelse af fremgangsmaaden - Google Patents

Fremgangsmaade til fremstilling af thienamycin og mellemprodukter til brug ved udoevelse af fremgangsmaaden

Info

Publication number
DK314280A
DK314280A DK314280A DK314280A DK314280A DK 314280 A DK314280 A DK 314280A DK 314280 A DK314280 A DK 314280A DK 314280 A DK314280 A DK 314280A DK 314280 A DK314280 A DK 314280A
Authority
DK
Denmark
Prior art keywords
procedure
thienamycine
intermediates
practice
preparation
Prior art date
Application number
DK314280A
Other languages
Danish (da)
English (en)
Inventor
B G Christensen
R W Ratcliffe
T N Salzmann
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/059,842 external-priority patent/US4273709A/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK314280A publication Critical patent/DK314280A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/10Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/02Preparation
    • C07D477/04Preparation by forming the ring or condensed ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK314280A 1979-07-23 1980-07-22 Fremgangsmaade til fremstilling af thienamycin og mellemprodukter til brug ved udoevelse af fremgangsmaaden DK314280A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5984379A 1979-07-23 1979-07-23
US06/059,842 US4273709A (en) 1979-07-23 1979-07-23 Process for the preparation of thienamycin and intermediates

Publications (1)

Publication Number Publication Date
DK314280A true DK314280A (da) 1981-01-24

Family

ID=26739255

Family Applications (1)

Application Number Title Priority Date Filing Date
DK314280A DK314280A (da) 1979-07-23 1980-07-22 Fremgangsmaade til fremstilling af thienamycin og mellemprodukter til brug ved udoevelse af fremgangsmaaden

Country Status (7)

Country Link
EP (1) EP0026817B1 (el)
DE (1) DE3067688D1 (el)
DK (1) DK314280A (el)
ES (1) ES8105708A1 (el)
GR (1) GR69717B (el)
IE (1) IE50071B1 (el)
PT (1) PT71552B (el)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE15039T1 (de) * 1979-04-27 1985-09-15 Merck & Co Inc Verfahren zur herstellung von 3-(1-hydroxyaethyl)- azetidinonen.
DE3879791T2 (de) * 1987-07-17 1993-10-14 Merck & Co Inc 4-Substituierte 3-Oxobutanoat-Esterderivate.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4174316A (en) * 1978-08-14 1979-11-13 Merck & Co., Inc. 4-Iodomethylazetidin-2-one
ATE15039T1 (de) * 1979-04-27 1985-09-15 Merck & Co Inc Verfahren zur herstellung von 3-(1-hydroxyaethyl)- azetidinonen.

Also Published As

Publication number Publication date
IE801504L (en) 1981-01-23
EP0026817B1 (en) 1984-05-02
PT71552B (en) 1981-12-14
GR69717B (el) 1982-07-09
ES493598A0 (es) 1981-06-16
IE50071B1 (en) 1986-02-05
EP0026817A1 (en) 1981-04-15
PT71552A (en) 1980-08-01
DE3067688D1 (en) 1984-06-07
ES8105708A1 (es) 1981-06-16

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Legal Events

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