DK3129350T3 - Makrocyklusser - Google Patents

Makrocyklusser Download PDF

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Publication number
DK3129350T3
DK3129350T3 DK15776966.2T DK15776966T DK3129350T3 DK 3129350 T3 DK3129350 T3 DK 3129350T3 DK 15776966 T DK15776966 T DK 15776966T DK 3129350 T3 DK3129350 T3 DK 3129350T3
Authority
DK
Denmark
Prior art keywords
macrocy
classes
macrocy classes
Prior art date
Application number
DK15776966.2T
Other languages
English (en)
Inventor
Nathaniel G Butlin
Darren Magda
Jide Xu
Original Assignee
Lumiphore Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lumiphore Inc filed Critical Lumiphore Inc
Application granted granted Critical
Publication of DK3129350T3 publication Critical patent/DK3129350T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/005Compounds of elements of Group 5 of the Periodic Table without metal-carbon linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08Bridged systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D259/00Heterocyclic compounds containing rings having more than four nitrogen atoms as the only ring hetero atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/22Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/60Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK15776966.2T 2014-04-09 2015-04-01 Makrocyklusser DK3129350T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461977301P 2014-04-09 2014-04-09
PCT/US2015/023818 WO2015157057A1 (en) 2014-04-09 2015-04-01 Macrocycles

Publications (1)

Publication Number Publication Date
DK3129350T3 true DK3129350T3 (da) 2021-11-22

Family

ID=54288276

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15776966.2T DK3129350T3 (da) 2014-04-09 2015-04-01 Makrocyklusser

Country Status (7)

Country Link
US (2) US11691997B2 (da)
EP (1) EP3129350B1 (da)
AU (1) AU2015244201B2 (da)
CA (1) CA2945034C (da)
DK (1) DK3129350T3 (da)
ES (1) ES2898633T3 (da)
WO (1) WO2015157057A1 (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2898633T3 (es) 2014-04-09 2022-03-08 Lumiphore Inc Macrociclos
US10434186B2 (en) 2014-12-22 2019-10-08 Lumiphore, Inc. Functionalized linear ligands and complexes thereof
HUE057041T2 (hu) 2015-07-06 2022-04-28 Alkermes Inc Hiszton deacetiláz hetero-halogén gátlói
WO2017007755A1 (en) 2015-07-06 2017-01-12 Rodin Therapeutics, Inc. Heterobicyclic n-aminophenyl-amides as inhibitors of histone deacetylase
AU2017321979B2 (en) 2016-09-02 2022-11-10 Lumiphore, Inc. Macrocyclic ligands with pendant chelating moieties and complexes thereof
MD3570834T2 (ro) 2017-01-11 2022-04-30 Alkermes Inc Inhibitori biciclici ai histon deacetilazei
WO2019032528A1 (en) 2017-08-07 2019-02-14 Rodin Therapeutics, Inc BICYCLIC HISTONE DEACETYLASE INHIBITORS
JP2021514052A (ja) 2018-02-15 2021-06-03 プロサイズディーエックス インコーポレーテッド アッセイキュベット
EP3752819B1 (en) 2018-02-15 2023-08-09 ProciseDx Inc. Analyzer
EP3762042A4 (en) 2018-03-07 2021-12-22 Lumiphore, Inc. MACROCYCLIC LIGANDS WITH PENDANT CHELATING FRACTIONS AND THEIR COMPLEXES
US11798700B2 (en) 2018-03-26 2023-10-24 The University Of British Columbia Systems, apparatus and methods for separating actinium, radium, and thorium
US20210290787A1 (en) * 2018-06-19 2021-09-23 Lumiphore, Inc. Macrocycle conjugates
JP2022532381A (ja) 2019-05-16 2022-07-14 プロサイセデクス インコーポレイティド Vcam-1及びカルプロテクチンのための分析検出方法
EP3821250B1 (en) 2019-05-16 2022-05-04 ProciseDx Inc. An assay method for the detection of vcam-1 and alpha-2-macroglobulin in blood
EP3973290A1 (en) 2019-05-23 2022-03-30 ProciseDx Inc. Assay methods for the detection of human serum albumin, vitamin d, c-reactive protein, and anti-transglutaminase autoantibody
EP3980779A1 (en) 2019-06-06 2022-04-13 ProciseDx Inc. Detection of hemoglobin a1c (hba1c) in blood
JP2022540764A (ja) 2019-06-25 2022-09-20 プロサイセデクス インコーポレイティド 抗TNFα生物製剤および抗薬剤抗体の検出
JP2022538169A (ja) 2019-06-28 2022-08-31 プロサイセデクス インコーポレイティド 光測定アッセイにおける試料マトリックス効果に対処するための方法
WO2021222533A1 (en) 2020-04-30 2021-11-04 Procisedx Inc. Methods of detecting antibodies to sars-cov-2
WO2021242725A1 (en) 2020-05-28 2021-12-02 Procisedx Inc. Predetermined calibration curve

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5049280A (en) 1989-03-29 1991-09-17 The Regents Of The University Of California 2,3-dihydroxyterephthalamides as highly effective metal ion sequestering compounds
US5624901A (en) 1994-04-15 1997-04-29 The Regents Of The University Of California 3-hydroxy-2(1H)-pyridinone chelating agents
AU762754B2 (en) 1999-02-18 2003-07-03 Regents Of The University Of California, The Salicylamide-lanthanide complexes for use as luminescent markers
US6515113B2 (en) 1999-02-18 2003-02-04 The Regents Of The University Of California Phthalamide lanthanide complexes for use as luminescent markers
US6846915B2 (en) 2001-08-13 2005-01-25 The Regents Of The University Of California Hydroxypyridonate and hydroxypyrimidinone chelating agents
AU2007272604B2 (en) 2006-07-10 2013-08-01 The Regents Of The University Of California Luminescent 1-hydroxy-2-pyridinone chelates of lanthanides
CA2660800C (en) 2006-08-15 2016-03-01 The Regents Of The University Of California Luminescent macrocyclic lanthanide complexes
EP2114905B1 (en) 2007-01-25 2015-04-15 Lumiphore, Inc. Multi-color time resolved fluorophores based on macrocyclic lanthanide complexes
EP2816038B8 (en) 2009-08-24 2019-12-25 Lumiphore, Inc. Hopo chelators
WO2011079291A1 (en) * 2009-12-24 2011-06-30 Lumiphore, Inc. Radiopharmaceutical complexes
US9439984B2 (en) * 2012-05-31 2016-09-13 The Regents Of The University Of California Macrocycles
CA2891593C (en) 2012-11-16 2021-09-14 Lumiphore, Inc. Di-macrocycles
ES2898633T3 (es) 2014-04-09 2022-03-08 Lumiphore Inc Macrociclos

Also Published As

Publication number Publication date
CA2945034A1 (en) 2015-10-15
WO2015157057A1 (en) 2015-10-15
ES2898633T3 (es) 2022-03-08
US10273256B2 (en) 2019-04-30
US20180298040A1 (en) 2018-10-18
AU2015244201A1 (en) 2016-10-20
CA2945034C (en) 2024-03-05
US20170183365A1 (en) 2017-06-29
EP3129350A4 (en) 2017-09-27
US11691997B2 (en) 2023-07-04
EP3129350B1 (en) 2021-10-27
AU2015244201B2 (en) 2019-09-12
EP3129350A1 (en) 2017-02-15

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