DK3083970T3 - Fremgangsmåde til oprensning af kappebærende virusser eller virale vektorer - Google Patents

Fremgangsmåde til oprensning af kappebærende virusser eller virale vektorer Download PDF

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Publication number
DK3083970T3
DK3083970T3 DK14828237T DK14828237T DK3083970T3 DK 3083970 T3 DK3083970 T3 DK 3083970T3 DK 14828237 T DK14828237 T DK 14828237T DK 14828237 T DK14828237 T DK 14828237T DK 3083970 T3 DK3083970 T3 DK 3083970T3
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DK
Denmark
Prior art keywords
procedure
viral vectors
cleaning coat
carrying viruses
viruses
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DK14828237T
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English (en)
Inventor
Driss Boudeffa
Otto-Wilhelm Merten
David Fenard
Original Assignee
Genethon
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50933209&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3083970(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genethon filed Critical Genethon
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Publication of DK3083970T3 publication Critical patent/DK3083970T3/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/15043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15051—Methods of production or purification of viral material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16051—Methods of production or purification of viral material

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
DK14828237T 2013-12-17 2014-12-17 Fremgangsmåde til oprensning af kappebærende virusser eller virale vektorer DK3083970T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1362835A FR3014901B1 (fr) 2013-12-17 2013-12-17 Procede de purification de virus ou vecteurs viraux enveloppes
PCT/FR2014/053406 WO2015092287A1 (fr) 2013-12-17 2014-12-17 Procédé de purification de virus ou vecteurs viraux enveloppes

Publications (1)

Publication Number Publication Date
DK3083970T3 true DK3083970T3 (da) 2019-11-11

Family

ID=50933209

Family Applications (1)

Application Number Title Priority Date Filing Date
DK14828237T DK3083970T3 (da) 2013-12-17 2014-12-17 Fremgangsmåde til oprensning af kappebærende virusser eller virale vektorer

Country Status (9)

Country Link
US (1) US10465169B2 (da)
EP (1) EP3083970B2 (da)
JP (1) JP6553043B2 (da)
CN (1) CN105980571A (da)
DK (1) DK3083970T3 (da)
ES (1) ES2753300T3 (da)
FR (1) FR3014901B1 (da)
SG (1) SG11201605805RA (da)
WO (1) WO2015092287A1 (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3010720B1 (fr) 2013-09-16 2017-08-11 Genethon Procede de production de virus enveloppes
CN116162658A (zh) * 2015-11-19 2023-05-26 诺华股份有限公司 用于稳定慢病毒制剂的缓冲液
WO2017180724A1 (en) 2016-04-12 2017-10-19 Artemis Biosystems, Inc. Perfusion filtration systems
CN108524929B (zh) * 2017-03-06 2019-05-07 广州瑞贝斯药业有限公司 一种狂犬病疫苗的生产方法
CN107630037A (zh) * 2017-10-19 2018-01-26 和元生物技术（上海）股份有限公司 一种获得高纯度腺相关病毒载体的纯化工艺
CN110317832B (zh) * 2018-03-28 2022-07-05 西比曼生物科技（香港）有限公司 Gmp级规模化制备重组慢病毒载体的纯化制剂的方法
CN110317791A (zh) 2018-03-29 2019-10-11 西比曼生物科技（香港）有限公司 Gmp级无血清悬浮细胞大规模生产慢病毒的方法
GB201806736D0 (en) * 2018-04-25 2018-06-06 Ge Healthcare Bioprocess R&D Ab Method for virus purification
US11529413B2 (en) 2018-06-12 2022-12-20 Kbio Holdings Limited Virus and antigen purification and conjugation
AU2019286406B2 (en) 2018-06-12 2023-04-13 Kbio Holdings Limited Virus and antigen purification and conjugation
US11696948B2 (en) 2018-06-12 2023-07-11 Kbio Holdings Limited Vaccines formed by virus and antigen conjugation
EP3581646A1 (en) * 2018-06-15 2019-12-18 Themis Bioscience GmbH Integrated manufacturing and chromatographic system for virus production
JP2021528999A (ja) * 2018-07-04 2021-10-28 プロバイオジェン アーゲー エンベロープウイルスの精製方法
US20220243224A1 (en) * 2019-04-15 2022-08-04 Children's Hospital Medical Center Viral vector manufacturing methods
CN110499287B (zh) * 2019-08-30 2021-07-23 博雅干细胞科技有限公司 简易制备胎盘间充质干细胞外泌体的方法
CN110540956B (zh) * 2019-08-30 2021-07-20 博雅干细胞科技有限公司 由胎盘间充质干细胞简易制备细胞因子的方法
US20240076631A2 (en) 2020-02-27 2024-03-07 Takeda Vaccines, Inc. Method for removing host cell dna from virus preparation
CN111876393A (zh) * 2020-06-30 2020-11-03 恒瑞源正（上海）生物科技有限公司 一种大规模快速生产高纯度高活性慢病毒载体的方法
CN116590346B (zh) * 2020-09-15 2024-05-14 上海药明巨诺生物医药研发有限公司 一种慢病毒载体纯化方法
CN113373120B (zh) * 2021-06-18 2022-04-26 浙江康佰裕生物科技有限公司 Gmp级逆转录病毒载体的纯化方法与应用
WO2023031858A1 (en) * 2021-09-01 2023-03-09 Glaxosmithkline Biologicals Sa Plasmid dna purification methods
WO2023177639A1 (en) * 2022-03-14 2023-09-21 Brammer Bio, Llc Lentiviral manufacturing platform
CN115505578A (zh) * 2022-09-20 2022-12-23 苏州博腾生物制药有限公司 可放大的用于纯化重组病毒的方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1358909A (fr) 1962-06-13 1964-04-17 Autelca Ag Installation téléphonique d'abonnés avec postes d'abonnés équipés avec un accumulateur
JPS63153016A (ja) 1987-11-10 1988-06-25 株式会社東芝 電気炊飯器
WO1989006276A2 (en) 1988-01-08 1989-07-13 Dpz Deutsches Primatenzentrum Gesellschaft Mbh Hiv-2-type retroviruses of primates, vaccines, diagnostic and pharmaceutical compositions
JPH09508017A (ja) † 1994-01-12 1997-08-19 ジェネティック セラピー，インコーポレイテッド レトロウイルスベクターの精製
EP1501921B2 (en) 2002-04-30 2012-07-25 Oncolytics Biotech Inc. Improved viral purification methods
EP1807511B1 (en) * 2004-11-05 2017-01-04 Wellstat Biologics Corporation Stable and filterable enveloped virus formulations
PL2007883T3 (pl) * 2006-04-20 2012-07-31 Wyeth Llc Sposób oczyszczania do izolacji oczyszczonego wirusa pęcherzykowatego zapalenia jamy ustnej z hodowli komórkowej
PL3192874T3 (pl) * 2008-06-18 2020-06-29 Oxford Biomedica (Uk) Limited Oczyszczanie wirusa
TWI469992B (zh) 2008-08-28 2015-01-21 Baxter Int 濃縮剪切靈敏生物聚合物的方法
EP2726497B1 (en) 2011-06-30 2017-06-21 Genethon Peptides with viral infection enhancing properties and their use
CN109097398A (zh) 2011-11-24 2018-12-28 吉尼松公司 与工业制药应用相容的可放大的慢病毒载体生产系统
FR3010720B1 (fr) 2013-09-16 2017-08-11 Genethon Procede de production de virus enveloppes
CN105829539B (zh) 2013-12-20 2023-11-10 帝斯曼营养品股份公司 从微生物中回收油的方法

Also Published As

Publication number Publication date
SG11201605805RA (en) 2016-09-29
CN105980571A (zh) 2016-09-28
EP3083970B1 (fr) 2019-09-04
WO2015092287A1 (fr) 2015-06-25
FR3014901A1 (fr) 2015-06-19
ES2753300T3 (es) 2020-04-08
JP2017503486A (ja) 2017-02-02
US10465169B2 (en) 2019-11-05
EP3083970B2 (fr) 2024-03-13
US20170002332A1 (en) 2017-01-05
FR3014901B1 (fr) 2017-06-09
EP3083970A1 (fr) 2016-10-26
JP6553043B2 (ja) 2019-07-31

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