DK3067093T3 - Anvendelse af en inhibitor af adrenomedullin til fremstilling af et lægemiddel egnet til forebyggelse og behandling af sygdomme, der reducerer knogletætheden - Google Patents

Anvendelse af en inhibitor af adrenomedullin til fremstilling af et lægemiddel egnet til forebyggelse og behandling af sygdomme, der reducerer knogletætheden Download PDF

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Publication number
DK3067093T3
DK3067093T3 DK15382111T DK15382111T DK3067093T3 DK 3067093 T3 DK3067093 T3 DK 3067093T3 DK 15382111 T DK15382111 T DK 15382111T DK 15382111 T DK15382111 T DK 15382111T DK 3067093 T3 DK3067093 T3 DK 3067093T3
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Prior art keywords
adrenomedullin
inhibitor
diseases
prevention
preparation
Prior art date
Application number
DK15382111T
Other languages
English (en)
Inventor
Ramírez Alfredo Martínez
Herrero Sonia Martínez
Roldán Ignacio Larráyoz
Callejero Laura Ochoa
Ledesma Luis José Fernández
Garrido Ignacio Ochoa
Josune García Sanmartín
Original Assignee
Fund Rioja Salud
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Application filed by Fund Rioja Salud filed Critical Fund Rioja Salud
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Publication of DK3067093T3 publication Critical patent/DK3067093T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4468Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245Oxadiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/433Thidiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/468-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK15382111T 2015-03-12 2015-03-12 Anvendelse af en inhibitor af adrenomedullin til fremstilling af et lægemiddel egnet til forebyggelse og behandling af sygdomme, der reducerer knogletætheden DK3067093T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP15382111.1A EP3067093B1 (en) 2015-03-12 2015-03-12 Use of an inhibitor of adrenomedullin for the manufacture of a drug useful in the prevention and treatment of diseases that reduce bone density

Publications (1)

Publication Number Publication Date
DK3067093T3 true DK3067093T3 (da) 2019-11-18

Family

ID=52737038

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15382111T DK3067093T3 (da) 2015-03-12 2015-03-12 Anvendelse af en inhibitor af adrenomedullin til fremstilling af et lægemiddel egnet til forebyggelse og behandling af sygdomme, der reducerer knogletætheden

Country Status (5)

Country Link
EP (1) EP3067093B1 (da)
DK (1) DK3067093T3 (da)
ES (1) ES2754478T3 (da)
PT (1) PT3067093T (da)
WO (1) WO2016142560A1 (da)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69602756T2 (de) * 1995-08-18 2000-02-10 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Rockville Funktionelle rolle von adrenomedullin(am) und dem gen-verwandten produkt(pamp) in der menschlichen pathologie und physiologie
US6440421B1 (en) * 1996-04-18 2002-08-27 Auchkland Uniservices Limited Treatment of bone disorders with adrenomedullin or adrenomedullin agonists
DE69836689D1 (de) * 1997-09-26 2007-02-01 Auckland Uniservices Ltd Verwendung von Amylin, Adrenomedullin und deren Analoga zur Behandlung von Knorpeldefekten
AU2004273057C1 (en) 2003-09-08 2011-06-30 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Non-peptide agonists and antagonists of adrenomedullin and gastrin releasing peptide

Also Published As

Publication number Publication date
ES2754478T3 (es) 2020-04-17
WO2016142560A1 (es) 2016-09-15
EP3067093B1 (en) 2019-08-07
EP3067093A1 (en) 2016-09-14
PT3067093T (pt) 2019-11-18

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