PT3067093T - Utilização de um inibidor de adrenomedulina para a produção de um fármaco útil na prevenção e tratamento de doenças que reduzem a densidade óssea - Google Patents
Utilização de um inibidor de adrenomedulina para a produção de um fármaco útil na prevenção e tratamento de doenças que reduzem a densidade ósseaInfo
- Publication number
- PT3067093T PT3067093T PT153821111T PT15382111T PT3067093T PT 3067093 T PT3067093 T PT 3067093T PT 153821111 T PT153821111 T PT 153821111T PT 15382111 T PT15382111 T PT 15382111T PT 3067093 T PT3067093 T PT 3067093T
- Authority
- PT
- Portugal
- Prior art keywords
- adrenomedullin
- inhibitor
- diseases
- prevention
- manufacture
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/433—Thidiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Emergency Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15382111.1A EP3067093B1 (en) | 2015-03-12 | 2015-03-12 | Use of an inhibitor of adrenomedullin for the manufacture of a drug useful in the prevention and treatment of diseases that reduce bone density |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3067093T true PT3067093T (pt) | 2019-11-18 |
Family
ID=52737038
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT153821111T PT3067093T (pt) | 2015-03-12 | 2015-03-12 | Utilização de um inibidor de adrenomedulina para a produção de um fármaco útil na prevenção e tratamento de doenças que reduzem a densidade óssea |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP3067093B1 (pt) |
| DK (1) | DK3067093T3 (pt) |
| ES (1) | ES2754478T3 (pt) |
| PT (1) | PT3067093T (pt) |
| WO (1) | WO2016142560A1 (pt) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6320022B1 (en) * | 1995-08-18 | 2001-11-20 | The United States Of America As Represented By The Department Of Health And Human Services | Adrenomedullin peptides |
| US6440421B1 (en) * | 1996-04-18 | 2002-08-27 | Auchkland Uniservices Limited | Treatment of bone disorders with adrenomedullin or adrenomedullin agonists |
| ATE348589T1 (de) * | 1997-09-26 | 2007-01-15 | Auckland Uniservices Ltd | Verwendung von amylin, adrenomedullin und deren analoga zur behandlung von knorpeldefekten |
| CA2539467C (en) | 2003-09-08 | 2012-11-13 | Frank Cuttitta | Non-peptide agonists and antagonists of adrenomedullin and gastric releasing peptide |
-
2015
- 2015-03-12 DK DK15382111T patent/DK3067093T3/da active
- 2015-03-12 EP EP15382111.1A patent/EP3067093B1/en active Active
- 2015-03-12 ES ES15382111T patent/ES2754478T3/es active Active
- 2015-03-12 PT PT153821111T patent/PT3067093T/pt unknown
-
2016
- 2016-03-14 WO PCT/ES2016/000035 patent/WO2016142560A1/es active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| EP3067093B1 (en) | 2019-08-07 |
| DK3067093T3 (da) | 2019-11-18 |
| WO2016142560A1 (es) | 2016-09-15 |
| EP3067093A1 (en) | 2016-09-14 |
| ES2754478T3 (es) | 2020-04-17 |
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