DK2987798T3 - Trehalosederivater og farmaceutiske sammensætninger til behandling af neurodegenerative sygdomme, der indeholder disse - Google Patents
Trehalosederivater og farmaceutiske sammensætninger til behandling af neurodegenerative sygdomme, der indeholder disseInfo
- Publication number
- DK2987798T3 DK2987798T3 DK15186646.4T DK15186646T DK2987798T3 DK 2987798 T3 DK2987798 T3 DK 2987798T3 DK 15186646 T DK15186646 T DK 15186646T DK 2987798 T3 DK2987798 T3 DK 2987798T3
- Authority
- DK
- Denmark
- Prior art keywords
- trehaloside
- derivatives
- pharmaceutical compositions
- neurodegenerative diseases
- treating neurodegenerative
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/12—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/04—Disaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/08—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/02—Monosaccharides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020080071383A KR101021078B1 (ko) | 2008-07-22 | 2008-07-22 | 이노시톨 또는 트리할로스 유도체 및 이를 함유하는 퇴행성뇌신경계 질환 치료용 약학 조성물 |
| EP09800493A EP2321265A4 (en) | 2008-07-22 | 2009-03-23 | INOSITOL AND TREHALOSE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES COMPRISING THESE DERIVATIVES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2987798T3 true DK2987798T3 (da) | 2017-11-13 |
Family
ID=41570452
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15186646.4T DK2987798T3 (da) | 2008-07-22 | 2009-03-23 | Trehalosederivater og farmaceutiske sammensætninger til behandling af neurodegenerative sygdomme, der indeholder disse |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20110224423A1 (da) |
| EP (2) | EP2987798B1 (da) |
| JP (1) | JP5410522B2 (da) |
| KR (1) | KR101021078B1 (da) |
| DK (1) | DK2987798T3 (da) |
| WO (1) | WO2010011012A1 (da) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2608378T3 (es) | 2011-12-29 | 2017-04-10 | Huawei Technologies Co., Ltd. | Sistema y procedimiento de computación en la nube para gestionar recursos de almacenamiento asociados |
| US20140021157A1 (en) | 2012-07-20 | 2014-01-23 | Closure Systems International, Inc. | Lightweight closure and container package |
| US9084720B2 (en) | 2013-05-07 | 2015-07-21 | BioBlast Pharma Ltd. | Compositions and methods for treating oculopharyngeal muscular dystrophy |
| EP2994145B1 (en) | 2013-05-07 | 2023-01-04 | Bio Blast Pharma Ltd. | Treatment of oculopharyngeal muscular dystrophy by intravenous administration of trehalose |
| KR20160001419A (ko) | 2014-06-27 | 2016-01-06 | 포항공과대학교 산학협력단 | 양이온성 분자 수송체 및 음이온성 생리활성 물질을 포함하는 피부 투과용 조성물 |
| KR20160095849A (ko) | 2015-02-04 | 2016-08-12 | 한남대학교 산학협력단 | 퇴행성 신경계 질환의 치료제 후보 물질 스크리닝 방법 |
| CN116600815A (zh) * | 2020-09-17 | 2023-08-15 | 株式会社力森诺科 | 自噬激活剂 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7521481B2 (en) | 2003-02-27 | 2009-04-21 | Mclaurin Joanne | Methods of preventing, treating and diagnosing disorders of protein aggregation |
| KR100578732B1 (ko) * | 2004-03-05 | 2006-05-12 | 학교법인 포항공과대학교 | 분자 수송체로서의 이노시톨 유도체 및 이의 제조방법 |
| KR100699279B1 (ko) * | 2005-04-28 | 2007-03-23 | 학교법인 포항공과대학교 | 당 또는 당 유사체를 골격으로 하는 분자 수송체 및 그의제조방법 |
| KR100849033B1 (ko) * | 2006-09-07 | 2008-07-29 | 포항공과대학교 산학협력단 | 알디톨 또는 이노시톨 유도체를 골격으로 한 분자 수송체 |
| JP2009511568A (ja) * | 2005-10-13 | 2009-03-19 | ワラタ ファーマシューティカルズ， インコーポレイテッド | イノシトール誘導体、ならびに異常なタンパク質の折りたたみまたは凝集、あるいはアミロイドの形成、沈着、蓄積または残存を特徴とする疾患の処置におけるその使用 |
-
2008
- 2008-07-22 KR KR1020080071383A patent/KR101021078B1/ko active IP Right Grant
-
2009
- 2009-03-23 US US13/003,414 patent/US20110224423A1/en not_active Abandoned
- 2009-03-23 EP EP15186646.4A patent/EP2987798B1/en not_active Not-in-force
- 2009-03-23 DK DK15186646.4T patent/DK2987798T3/da active
- 2009-03-23 JP JP2011519969A patent/JP5410522B2/ja not_active Expired - Fee Related
- 2009-03-23 EP EP09800493A patent/EP2321265A4/en not_active Withdrawn
- 2009-03-23 WO PCT/KR2009/001470 patent/WO2010011012A1/en active Application Filing
-
2014
- 2014-10-08 US US14/509,175 patent/US9371350B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP2321265A4 (en) | 2012-04-04 |
| US20110224423A1 (en) | 2011-09-15 |
| KR101021078B1 (ko) | 2011-03-14 |
| EP2987798B1 (en) | 2017-08-09 |
| KR20100010418A (ko) | 2010-02-01 |
| US9371350B2 (en) | 2016-06-21 |
| JP2011529044A (ja) | 2011-12-01 |
| WO2010011012A1 (en) | 2010-01-28 |
| US20150025035A1 (en) | 2015-01-22 |
| EP2987798A1 (en) | 2016-02-24 |
| JP5410522B2 (ja) | 2014-02-05 |
| EP2321265A1 (en) | 2011-05-18 |
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| DK2987798T3 (da) | Trehalosederivater og farmaceutiske sammensætninger til behandling af neurodegenerative sygdomme, der indeholder disse |