DK2968218T3 - Kombination til behandling af parkinsons sygdom - Google Patents

Kombination til behandling af parkinsons sygdom Download PDF

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Publication number
DK2968218T3
DK2968218T3 DK14718177.0T DK14718177T DK2968218T3 DK 2968218 T3 DK2968218 T3 DK 2968218T3 DK 14718177 T DK14718177 T DK 14718177T DK 2968218 T3 DK2968218 T3 DK 2968218T3
Authority
DK
Denmark
Prior art keywords
parkinson
disease
treatment
combination
Prior art date
Application number
DK14718177.0T
Other languages
Danish (da)
English (en)
Inventor
Oron Yacoby-Zeevi
Original Assignee
Neuroderm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50513395&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2968218(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Neuroderm Ltd filed Critical Neuroderm Ltd
Application granted granted Critical
Publication of DK2968218T3 publication Critical patent/DK2968218T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/121—Ketones acyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Psychology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Otolaryngology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK14718177.0T 2013-03-13 2014-03-13 Kombination til behandling af parkinsons sygdom DK2968218T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361779357P 2013-03-13 2013-03-13
PCT/IL2014/050261 WO2014141261A1 (en) 2013-03-13 2014-03-13 Method for treatment of parkinson's disease

Publications (1)

Publication Number Publication Date
DK2968218T3 true DK2968218T3 (da) 2021-09-20

Family

ID=50513395

Family Applications (1)

Application Number Title Priority Date Filing Date
DK14718177.0T DK2968218T3 (da) 2013-03-13 2014-03-13 Kombination til behandling af parkinsons sygdom

Country Status (21)

Country Link
US (4) US20160022573A1 (cg-RX-API-DMAC10.html)
EP (2) EP3892266A1 (cg-RX-API-DMAC10.html)
JP (2) JP6472391B2 (cg-RX-API-DMAC10.html)
KR (1) KR102209353B1 (cg-RX-API-DMAC10.html)
CN (2) CN110935026A (cg-RX-API-DMAC10.html)
AU (1) AU2014229127B2 (cg-RX-API-DMAC10.html)
BR (1) BR112015022390A8 (cg-RX-API-DMAC10.html)
CA (1) CA2904838C (cg-RX-API-DMAC10.html)
CL (1) CL2015002641A1 (cg-RX-API-DMAC10.html)
DK (1) DK2968218T3 (cg-RX-API-DMAC10.html)
ES (1) ES2889626T3 (cg-RX-API-DMAC10.html)
HR (1) HRP20211442T1 (cg-RX-API-DMAC10.html)
HU (1) HUE056006T2 (cg-RX-API-DMAC10.html)
IL (1) IL266648B (cg-RX-API-DMAC10.html)
MX (1) MX365206B (cg-RX-API-DMAC10.html)
PL (1) PL2968218T3 (cg-RX-API-DMAC10.html)
PT (1) PT2968218T (cg-RX-API-DMAC10.html)
RU (2) RU2677278C2 (cg-RX-API-DMAC10.html)
SG (2) SG11201507538UA (cg-RX-API-DMAC10.html)
WO (1) WO2014141261A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA201507621B (cg-RX-API-DMAC10.html)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3192500T (pt) 2009-05-19 2021-01-05 Neuroderm Ltd Composições para a administração contínua de inibidores da dopa decarboxilase
DK2640358T3 (en) 2010-11-15 2018-04-16 Neuroderm Ltd CONTINUOUS ADMINISTRATION OF L-DOPA, DOPA-DECARBOXYLASE INHIBITORS, CATECHOL-O-METHYL TRANSFERASE INHIBITORS AND COMPOSITIONS THEREOF
WO2012066537A2 (en) 2010-11-15 2012-05-24 Neuroderm Ltd Compositions for transdermal delivery of active agents
US10258585B2 (en) 2014-03-13 2019-04-16 Neuroderm, Ltd. DOPA decarboxylase inhibitor compositions
PL3777833T3 (pl) * 2014-03-13 2024-03-25 Neuroderm Ltd. Kompozycje inhibitorów dekarboksylazy dopa
PT3782617T (pt) 2014-09-04 2024-02-29 Lobsor Pharmaceuticals Ab Composições farmacêuticas de gel compreendendo levodopa, carbidopa e entacapona
ES2739536T3 (es) 2014-10-21 2020-01-31 Abbvie Inc Profármacos de carbidopa y L-dopa y su uso para tratar la enfermedad de Parkinson
MA41377A (fr) 2015-01-20 2017-11-28 Abbvie Inc Gel intestinal de lévodopa et de carbidona et procédés d'utilisation
WO2017039525A1 (en) * 2015-09-04 2017-03-09 Lobsor Pharmaceuticals Aktiebolag Method of treating a dopamine related disorder in a subject by administering levodopa, in combination with a dopamine decarboxylase inhibitor and a catechol-o-methyltransferase inhibitor
WO2017070293A1 (en) * 2015-10-20 2017-04-27 Ironwood Pharmaceuticals, Inc. Phosphodiesterase 9 inhibitor and levodopa therapy
EP3275433A1 (en) * 2016-07-29 2018-01-31 Som Innovation Biotech S.L. Sustained release composition comprising micronized tolcapone
IL271169B (en) * 2017-06-05 2022-09-01 Dizlin Pharmaceuticals Ab An infusion of levodopa
WO2019097120A1 (en) * 2017-11-16 2019-05-23 Orion Corporation New use and pharmaceutical dosage forms
WO2019147934A1 (en) * 2018-01-29 2019-08-01 Sackner Bernstein Jonathan Methods for dopamine modulation in human neurologic diseases
EP3773532A4 (en) * 2018-03-29 2022-11-02 Avion Pharmaceuticals, LLC FRACTIONAL LEVODOPA DOSAGE AND USE
TW202031265A (zh) 2018-11-15 2020-09-01 美商艾伯維有限公司 用於皮下投藥之醫藥調配物
CN111701024B (zh) * 2020-05-26 2022-05-24 上海京新生物医药有限公司 一种左旋多巴制剂及其制备方法及其应用
WO2022047298A1 (en) * 2020-08-31 2022-03-03 Purdue Pharma L.P. Compositions and methods for levodopa delivery
US11213502B1 (en) 2020-11-17 2022-01-04 Neuroderm, Ltd. Method for treatment of parkinson's disease
US11331293B1 (en) 2020-11-17 2022-05-17 Neuroderm, Ltd. Method for treatment of Parkinson's disease
US11844754B2 (en) 2020-11-17 2023-12-19 Neuroderm, Ltd. Methods for treatment of Parkinson's disease
WO2023282900A1 (en) * 2021-07-08 2023-01-12 Morehouse School Of Medicine Method and system of diagnosing and treating neurodegenerative disease and seizures
US12161612B2 (en) 2023-04-14 2024-12-10 Neuroderm, Ltd. Methods and compositions for reducing symptoms of Parkinson's disease

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4166452A (en) 1976-05-03 1979-09-04 Generales Constantine D J Jr Apparatus for testing human responses to stimuli
US4256108A (en) 1977-04-07 1981-03-17 Alza Corporation Microporous-semipermeable laminated osmotic system
US4265874A (en) 1980-04-25 1981-05-05 Alza Corporation Method of delivering drug with aid of effervescent activity generated in environment of use
US4832957A (en) * 1987-12-11 1989-05-23 Merck & Co., Inc. Controlled release combination of carbidopa/levodopa
FI109453B (fi) * 1999-06-30 2002-08-15 Orion Yhtymae Oyj Farmaseuttinen koostumus
EP2335696A1 (en) * 2005-06-08 2011-06-22 Orion Corporation An entacapone-containing oral dosage form
TR200806646A2 (tr) * 2008-09-03 2009-06-22 Dr. F. Fri̇k İlaç San. Ve Ti̇c. A.Ş. Entakapon, levodopa ve karbidoba içeren farmasötik kombinasyonlar
PT3192500T (pt) * 2009-05-19 2021-01-05 Neuroderm Ltd Composições para a administração contínua de inibidores da dopa decarboxilase
DK2640358T3 (en) * 2010-11-15 2018-04-16 Neuroderm Ltd CONTINUOUS ADMINISTRATION OF L-DOPA, DOPA-DECARBOXYLASE INHIBITORS, CATECHOL-O-METHYL TRANSFERASE INHIBITORS AND COMPOSITIONS THEREOF

Also Published As

Publication number Publication date
MX2015012561A (es) 2016-06-28
US20160022573A1 (en) 2016-01-28
KR20150131230A (ko) 2015-11-24
SG11201507538UA (en) 2015-10-29
AU2014229127B2 (en) 2018-04-05
US20230047847A1 (en) 2023-02-16
MX365206B (es) 2019-05-27
PT2968218T (pt) 2021-09-24
JP2016512230A (ja) 2016-04-25
EP3892266A1 (en) 2021-10-13
CN105209029A (zh) 2015-12-30
HUE056006T2 (hu) 2022-01-28
EP2968218B1 (en) 2021-07-07
CL2015002641A1 (es) 2016-03-18
US20210093560A1 (en) 2021-04-01
IL266648B (en) 2020-08-31
HRP20211442T1 (hr) 2022-02-04
JP6472391B2 (ja) 2019-02-20
US20250177292A1 (en) 2025-06-05
BR112015022390A8 (pt) 2019-11-26
WO2014141261A1 (en) 2014-09-18
EP2968218A1 (en) 2016-01-20
RU2015143112A (ru) 2017-04-20
CA2904838C (en) 2021-03-16
ZA201507621B (en) 2019-04-24
KR102209353B1 (ko) 2021-01-29
JP6625773B2 (ja) 2019-12-25
SG10201911731YA (en) 2020-02-27
BR112015022390A2 (pt) 2017-07-18
RU2018144700A (ru) 2019-02-18
IL266648A (en) 2019-07-31
AU2014229127A1 (en) 2015-11-05
CN110935026A (zh) 2020-03-31
PL2968218T3 (pl) 2022-01-10
CA2904838A1 (en) 2014-09-18
JP2019070041A (ja) 2019-05-09
RU2677278C2 (ru) 2019-01-16
ES2889626T3 (es) 2022-01-12

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