DK2938346T3 - APPLICATION OF PREGN-4-EN-20-YN-3-ON FOR THE TREATMENT OF DEPRESSIVE DISORDERS - Google Patents

APPLICATION OF PREGN-4-EN-20-YN-3-ON FOR THE TREATMENT OF DEPRESSIVE DISORDERS Download PDF

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Publication number
DK2938346T3
DK2938346T3 DK13819136.6T DK13819136T DK2938346T3 DK 2938346 T3 DK2938346 T3 DK 2938346T3 DK 13819136 T DK13819136 T DK 13819136T DK 2938346 T3 DK2938346 T3 DK 2938346T3
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DK
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Prior art keywords
pregn
depressive disorder
subject
nasal
treatment
Prior art date
Application number
DK13819136.6T
Other languages
Danish (da)
English (en)
Inventor
Louis Monti
Original Assignee
Pherin Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pherin Pharm Inc filed Critical Pherin Pharm Inc
Application granted granted Critical
Publication of DK2938346T3 publication Critical patent/DK2938346T3/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Otolaryngology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK13819136.6T 2012-12-28 2013-12-19 APPLICATION OF PREGN-4-EN-20-YN-3-ON FOR THE TREATMENT OF DEPRESSIVE DISORDERS DK2938346T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261747167P 2012-12-28 2012-12-28
PCT/US2013/076497 WO2014105620A1 (en) 2012-12-28 2013-12-19 Use of pregn-4-en-20-yn-3-one for the treatment of depressive disorders

Publications (1)

Publication Number Publication Date
DK2938346T3 true DK2938346T3 (en) 2017-06-12

Family

ID=49950051

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13819136.6T DK2938346T3 (en) 2012-12-28 2013-12-19 APPLICATION OF PREGN-4-EN-20-YN-3-ON FOR THE TREATMENT OF DEPRESSIVE DISORDERS

Country Status (11)

Country Link
US (1) US10322138B2 (OSRAM)
EP (1) EP2938346B1 (OSRAM)
JP (1) JP6283689B2 (OSRAM)
KR (1) KR102209475B1 (OSRAM)
CN (1) CN104936600B (OSRAM)
AU (1) AU2013371025B2 (OSRAM)
CA (1) CA2894686C (OSRAM)
DK (1) DK2938346T3 (OSRAM)
ES (1) ES2625778T3 (OSRAM)
MX (1) MX369774B (OSRAM)
WO (1) WO2014105620A1 (OSRAM)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210393621A1 (en) 2018-10-26 2021-12-23 The Research Foundation For The State University Of New York Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia
ES2972282T3 (es) * 2019-04-15 2024-06-12 Vistagen Therapeutics Inc Tratamiento de la migraña
WO2024254005A1 (en) 2023-06-04 2024-12-12 Vistagen Therapeutics, Inc. 1,3,5(10),16-estratetraen-3-yl acetate for use in improving psychomotor or cognitive performance
US20250312356A1 (en) * 2024-04-08 2025-10-09 Vistagen Therapeutics, Inc. Treatment of dysmenorrhea

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5303703A (en) 1991-10-03 1994-04-19 Pherin Corporation Combined neuroepithelial sample delivery electrode device and methods of using same
EP1340502A3 (en) * 1993-06-15 2004-01-21 Pherin Corporation Androstane steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods
US6066627A (en) 1994-08-04 2000-05-23 Pherin Corporation Steroids as neurochemical initiators of change in human blood levels of LH
US5563131A (en) * 1994-08-04 1996-10-08 Pherin Corporation Pregnane steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods
US5994333A (en) 1994-08-04 1999-11-30 Pherin Corporation Pregnane and cholane steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods
US6117860A (en) 1994-08-04 2000-09-12 Pherin Pharmaceuticals, Inc. Steroids as neurochemical stimulators of the VNO to treat paroxistic tachycardia
US6057439A (en) 1994-08-04 2000-05-02 Pherin Corporation Steroids as neurochemical stimulators of the VNO to alleviate symptoms of PMS and anxiety
US6331534B1 (en) 1994-08-04 2001-12-18 Pherin Pharmaceuticals, Inc. Steroids as neurochemical stimulators of the VNO to alleviate pain
JP4450435B2 (ja) * 1996-07-23 2010-04-14 フィーリン・ファーマシューティカルズ・インコーポレイテッド Pmsおよび不安の症状を緩和する、vnoにおける神経化学刺激物質としてのステロイド
US20020123138A1 (en) * 2000-11-30 2002-09-05 Jian Zhang Human VNO receptor (R1)
US20030045514A1 (en) 2001-05-03 2003-03-06 Louis Monti 17-Methyleneandrostan-3alpha-ol analogs as CRH inhibitors

Also Published As

Publication number Publication date
CA2894686A1 (en) 2014-07-03
CN104936600B (zh) 2018-08-03
EP2938346A1 (en) 2015-11-04
KR20150100884A (ko) 2015-09-02
MX369774B (es) 2019-11-21
WO2014105620A1 (en) 2014-07-03
CN104936600A (zh) 2015-09-23
EP2938346B1 (en) 2017-04-05
MX2015008454A (es) 2016-05-16
CA2894686C (en) 2021-05-04
US20140187524A1 (en) 2014-07-03
HK1210421A1 (en) 2016-04-22
JP2016504361A (ja) 2016-02-12
AU2013371025B2 (en) 2018-01-18
AU2013371025A1 (en) 2015-07-09
KR102209475B1 (ko) 2021-01-28
ES2625778T3 (es) 2017-07-20
JP6283689B2 (ja) 2018-02-21
US10322138B2 (en) 2019-06-18

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