DK2799091T3 - System, indretning og fremgangsmåde til fremstilling af tracere og overførsel af materialer under radiosyntese - Google Patents

System, indretning og fremgangsmåde til fremstilling af tracere og overførsel af materialer under radiosyntese Download PDF

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Publication number
DK2799091T3
DK2799091T3 DK14174712.1T DK14174712T DK2799091T3 DK 2799091 T3 DK2799091 T3 DK 2799091T3 DK 14174712 T DK14174712 T DK 14174712T DK 2799091 T3 DK2799091 T3 DK 2799091T3
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container
line
reaction
solution
communication
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DK14174712.1T
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English (en)
Inventor
Carroll Edward Ball
Arkadij M Elizarov
Umesh B Gangadharmath
Hartmuth C Kolb
Ricardo Rodriguez
Joseph C Walsh
Original Assignee
Lilly Co Eli
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Publication of DK2799091T3 publication Critical patent/DK2799091T3/da

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0006—Controlling or regulating processes
    • B01J19/004—Multifunctional apparatus for automatic manufacturing of various chemical products
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/082—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being a RGD-containing peptide
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J4/00—Feed or outlet devices; Feed or outlet control devices
    • B01J4/008—Feed or outlet control devices
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/8593—Systems
    • Y10T137/85978—With pump
    • Y10T137/86035—Combined with fluid receiver

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Manufacturing & Machinery (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Measuring Volume Flow (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)

Claims (4)

1. Forbindelse, som er
eller et farmaceutisk acceptabelt salt deraf, hvor *F er F eller 18F.
2. Forbindelse, som er 7-(6-nitropyridin-3-yl)-5H-pyrido[4,3-b]indol:
eller farmaceutisk acceptable salte deraf.
3.
Fremgangsmåde til fremstilling af 7-[6-(18F)fluorpyridin-3-yl]-5/-/-pyrido[4,3-£>]indole, omfattende at reagere 7-(6-nitropyridin-3-yl)-5/-/-pyrido[4,3-b]indol med vandfri [F-18] fluorid-ion.
DK14174712.1T 2011-04-13 2012-04-13 System, indretning og fremgangsmåde til fremstilling af tracere og overførsel af materialer under radiosyntese DK2799091T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161474804P 2011-04-13 2011-04-13
US201161497190P 2011-06-15 2011-06-15
US13/445,147 US10639608B2 (en) 2010-04-08 2012-04-12 System, device and method for preparing tracers and transferring materials during radiosynthesis
EP20120164172 EP2511006A2 (en) 2011-04-13 2012-04-13 System, device and method for preparing tracers and transferring materials during radiosynthesis

Publications (1)

Publication Number Publication Date
DK2799091T3 true DK2799091T3 (da) 2016-10-03

Family

ID=46000897

Family Applications (1)

Application Number Title Priority Date Filing Date
DK14174712.1T DK2799091T3 (da) 2011-04-13 2012-04-13 System, indretning og fremgangsmåde til fremstilling af tracere og overførsel af materialer under radiosyntese

Country Status (12)

Country Link
US (1) US10639608B2 (da)
EP (2) EP2511006A2 (da)
CY (1) CY1117988T1 (da)
DK (1) DK2799091T3 (da)
ES (1) ES2593474T3 (da)
HR (1) HRP20161084T1 (da)
HU (1) HUE028893T2 (da)
LT (1) LT2799091T (da)
PL (1) PL2799091T3 (da)
PT (1) PT2799091T (da)
RS (1) RS55077B1 (da)
SI (1) SI2799091T1 (da)

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GB201223178D0 (en) 2012-12-21 2013-02-06 Ge Healthcare Ltd Dose recordal
WO2014194169A1 (en) * 2013-05-31 2014-12-04 The General Hospital Corporation Radiosynthesis of tau radiopharmaceuticals
US9907867B2 (en) * 2013-09-26 2018-03-06 General Electric Company Systems, methods and apparatus for manufacturing radioisotopes
EP3068747A1 (en) * 2013-11-13 2016-09-21 GE Healthcare Limited Dual run cassette for the synthesis of 18f-labelled compounds
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WO2018089491A1 (en) * 2016-11-08 2018-05-17 The Regents Of The University Of California Methods for multi-dose synthesis of [f-18]fddnp for clinical settings
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US20200316230A1 (en) * 2019-04-08 2020-10-08 Vanderbilt University Devices and methods for radiopharmaceutical synthesis

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Also Published As

Publication number Publication date
LT2799091T (lt) 2016-10-10
EP2511006A2 (en) 2012-10-17
EP2799091A2 (en) 2014-11-05
HUE028893T2 (en) 2017-01-30
RS55077B1 (sr) 2016-12-30
US10639608B2 (en) 2020-05-05
EP2799091A3 (en) 2014-11-19
CY1117988T1 (el) 2017-05-17
US20120283490A1 (en) 2012-11-08
HRP20161084T1 (hr) 2016-11-04
PL2799091T3 (pl) 2017-01-31
PT2799091T (pt) 2016-09-02
EP2799091B1 (en) 2016-07-13
ES2593474T3 (es) 2016-12-09
SI2799091T1 (sl) 2016-08-31

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