PT2799091T - Sistema, dispositivo e método para preparar traçadores e transferir materiais durante a radiossíntese - Google Patents

Sistema, dispositivo e método para preparar traçadores e transferir materiais durante a radiossíntese

Info

Publication number
PT2799091T
PT2799091T PT141747121T PT14174712T PT2799091T PT 2799091 T PT2799091 T PT 2799091T PT 141747121 T PT141747121 T PT 141747121T PT 14174712 T PT14174712 T PT 14174712T PT 2799091 T PT2799091 T PT 2799091T
Authority
PT
Portugal
Prior art keywords
materials during
transferring materials
tracers
preparing
radiosynthesis
Prior art date
Application number
PT141747121T
Other languages
English (en)
Inventor
Edward Ball Carroll
M Elizarov Arkadij
B Gangadharmath Umesh
C Kolb Hartmuth
Rodriguez Ricardo
C Walsh Joseph
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of PT2799091T publication Critical patent/PT2799091T/pt

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0006—Controlling or regulating processes
    • B01J19/004—Multifunctional apparatus for automatic manufacturing of various chemical products
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/082—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being a RGD-containing peptide
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J4/00—Feed or outlet devices; Feed or outlet control devices
    • B01J4/008—Feed or outlet control devices
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/8593—Systems
    • Y10T137/85978—With pump
    • Y10T137/86035—Combined with fluid receiver

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Manufacturing & Machinery (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Measuring Volume Flow (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
PT141747121T 2011-04-13 2012-04-13 Sistema, dispositivo e método para preparar traçadores e transferir materiais durante a radiossíntese PT2799091T (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161474804P 2011-04-13 2011-04-13
US201161497190P 2011-06-15 2011-06-15
US13/445,147 US10639608B2 (en) 2010-04-08 2012-04-12 System, device and method for preparing tracers and transferring materials during radiosynthesis

Publications (1)

Publication Number Publication Date
PT2799091T true PT2799091T (pt) 2016-09-02

Family

ID=46000897

Family Applications (1)

Application Number Title Priority Date Filing Date
PT141747121T PT2799091T (pt) 2011-04-13 2012-04-13 Sistema, dispositivo e método para preparar traçadores e transferir materiais durante a radiossíntese

Country Status (12)

Country Link
US (1) US10639608B2 (pt)
EP (2) EP2511006A2 (pt)
CY (1) CY1117988T1 (pt)
DK (1) DK2799091T3 (pt)
ES (1) ES2593474T3 (pt)
HR (1) HRP20161084T1 (pt)
HU (1) HUE028893T2 (pt)
LT (1) LT2799091T (pt)
PL (1) PL2799091T3 (pt)
PT (1) PT2799091T (pt)
RS (1) RS55077B1 (pt)
SI (1) SI2799091T1 (pt)

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GB201420094D0 (en) 2014-11-12 2014-12-24 Ge Healthcare Ltd Flouride trapping arrangement
US8932557B2 (en) 2008-02-14 2015-01-13 Eli Lilly And Company Imaging agents for detecting neurological dysfunction
WO2013176698A1 (en) * 2012-05-22 2013-11-28 Eli Lilly And Company Carboline and carbazole based imaging agents for detecting neurological dysfunction
US20140072482A1 (en) * 2012-09-12 2014-03-13 Atomic Energy Council-Institute Of Nuclear Energy Research Automated synthesis system for iodine-123-ibzm nuclear medicine
ITTO20120996A1 (it) * 2012-11-16 2014-05-17 Consiglio Nazionale Ricerche Procedimento e impianto per la produzione di radiotraccianti pet 18f-fluorurati
GB201223178D0 (en) 2012-12-21 2013-02-06 Ge Healthcare Ltd Dose recordal
WO2014194169A1 (en) * 2013-05-31 2014-12-04 The General Hospital Corporation Radiosynthesis of tau radiopharmaceuticals
US9907867B2 (en) * 2013-09-26 2018-03-06 General Electric Company Systems, methods and apparatus for manufacturing radioisotopes
EP3068747A1 (en) * 2013-11-13 2016-09-21 GE Healthcare Limited Dual run cassette for the synthesis of 18f-labelled compounds
GB201420093D0 (en) * 2014-11-12 2014-12-24 Ge Healthcare Ltd Pet tracer purification system
FR3035262B1 (fr) * 2015-04-16 2020-02-07 P M B Dispositif de synthese d'un radio-traceur, installation comportant un tel dispositif et procede d'obtention d'un radio-traceur au moyen d'un tel dispositif
US11707538B2 (en) 2016-01-11 2023-07-25 Washington University Methods and devices to generate [F-18]triflyl fluoride and other [F-18] sulfonyl fluorides
US11242314B2 (en) * 2016-01-11 2022-02-08 Washington University Synthesizing pet tracers using [F-18]sulfonyl fluoride as a source of [F-18]fluoride
WO2018089491A1 (en) * 2016-11-08 2018-05-17 The Regents Of The University Of California Methods for multi-dose synthesis of [f-18]fddnp for clinical settings
US20180209921A1 (en) * 2017-01-20 2018-07-26 Mallinckrodt Nuclear Medicine Llc Systems and methods for assaying an eluate of a radionuclide generator
US20200000946A1 (en) * 2017-03-03 2020-01-02 The General Hospital Corporation Method and apparatus for preparing a radiolabeled pharmaceutical
US20200316230A1 (en) * 2019-04-08 2020-10-08 Vanderbilt University Devices and methods for radiopharmaceutical synthesis

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BE1010280A3 (fr) * 1996-05-02 1998-05-05 Coincidence S A Procede et dispositif de synthese de 2-[18f] fluoro-2-deoxy-d-glucose.
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EP2017359A3 (en) 2007-06-11 2009-08-05 Trasis S.A. Method for the elution of 18F fluoride trapped on an anion-exchange resin in a form suitable for efficient radiolabeling without any evaporation step
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Also Published As

Publication number Publication date
LT2799091T (lt) 2016-10-10
EP2511006A2 (en) 2012-10-17
DK2799091T3 (en) 2016-10-03
EP2799091A2 (en) 2014-11-05
HUE028893T2 (en) 2017-01-30
RS55077B1 (sr) 2016-12-30
US10639608B2 (en) 2020-05-05
EP2799091A3 (en) 2014-11-19
CY1117988T1 (el) 2017-05-17
US20120283490A1 (en) 2012-11-08
HRP20161084T1 (hr) 2016-11-04
PL2799091T3 (pl) 2017-01-31
EP2799091B1 (en) 2016-07-13
ES2593474T3 (es) 2016-12-09
SI2799091T1 (sl) 2016-08-31

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