DK2712610T3 - Fremgangsmåder til fremstilling af cykliske, lipidimplantater til intraokulær anvendelse - Google Patents

Fremgangsmåder til fremstilling af cykliske, lipidimplantater til intraokulær anvendelse

Info

Publication number
DK2712610T3
DK2712610T3 DK13179876.1T DK13179876T DK2712610T3 DK 2712610 T3 DK2712610 T3 DK 2712610T3 DK 13179876 T DK13179876 T DK 13179876T DK 2712610 T3 DK2712610 T3 DK 2712610T3
Authority
DK
Denmark
Prior art keywords
preparation
methods
cyclic lipid
implants
intraocular use
Prior art date
Application number
DK13179876.1T
Other languages
English (en)
Inventor
Lon T Spada
James N Chang
Michelle Luu
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Application granted granted Critical
Publication of DK2712610T3 publication Critical patent/DK2712610T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
DK13179876.1T 2006-12-19 2007-12-12 Fremgangsmåder til fremstilling af cykliske, lipidimplantater til intraokulær anvendelse DK2712610T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/612,928 US8846073B2 (en) 2006-12-19 2006-12-19 Low temperature processes for making cyclic lipid implants for intraocular use
EP07855073.8A EP2124879B1 (en) 2006-12-19 2007-12-12 Processes for making cyclic lipid implants for intraocular use

Publications (1)

Publication Number Publication Date
DK2712610T3 true DK2712610T3 (da) 2018-01-29

Family

ID=39467138

Family Applications (3)

Application Number Title Priority Date Filing Date
DK17198020.4T DK3308769T3 (da) 2006-12-19 2007-12-12 Fremgangsmåder til fremstilling af cykliske lipidimplantater til intraokulær anvendelse
DK07855073.8T DK2124879T3 (da) 2006-12-19 2007-12-12 Fremgangsmåder til fremstilling af cykliske lipidimplantater til intraokulær anvendelse
DK13179876.1T DK2712610T3 (da) 2006-12-19 2007-12-12 Fremgangsmåder til fremstilling af cykliske, lipidimplantater til intraokulær anvendelse

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DK17198020.4T DK3308769T3 (da) 2006-12-19 2007-12-12 Fremgangsmåder til fremstilling af cykliske lipidimplantater til intraokulær anvendelse
DK07855073.8T DK2124879T3 (da) 2006-12-19 2007-12-12 Fremgangsmåder til fremstilling af cykliske lipidimplantater til intraokulær anvendelse

Country Status (11)

Country Link
US (5) US8846073B2 (da)
EP (3) EP3308769B1 (da)
JP (2) JP5484911B2 (da)
AU (1) AU2007337139B2 (da)
CA (1) CA2673294C (da)
DK (3) DK3308769T3 (da)
ES (3) ES2588187T3 (da)
HK (1) HK1253728A1 (da)
HU (3) HUE053530T2 (da)
PL (3) PL2124879T3 (da)
WO (1) WO2008079674A2 (da)

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Also Published As

Publication number Publication date
US9149428B2 (en) 2015-10-06
EP3308769A1 (en) 2018-04-18
PL2712610T3 (pl) 2018-05-30
AU2007337139B2 (en) 2013-05-09
HUE030404T2 (en) 2017-05-29
US20200038326A1 (en) 2020-02-06
US10441543B2 (en) 2019-10-15
US8846073B2 (en) 2014-09-30
US20210322318A1 (en) 2021-10-21
JP5826872B2 (ja) 2015-12-02
CA2673294C (en) 2015-07-21
JP5484911B2 (ja) 2014-05-07
EP2712610A1 (en) 2014-04-02
JP2014088448A (ja) 2014-05-15
DK3308769T3 (da) 2021-02-01
HUE037939T2 (hu) 2018-09-28
EP3308769B1 (en) 2020-10-28
US20140364494A1 (en) 2014-12-11
EP2712610B1 (en) 2017-10-25
US20160022581A1 (en) 2016-01-28
CA2673294A1 (en) 2008-07-03
ES2588187T3 (es) 2016-10-31
HK1253728A1 (zh) 2019-06-28
AU2007337139A1 (en) 2008-07-03
US20080145403A1 (en) 2008-06-19
DK2124879T3 (da) 2016-09-05
HUE053530T2 (hu) 2021-07-28
ES2851748T3 (es) 2021-09-08
EP2124879B1 (en) 2016-05-25
WO2008079674A3 (en) 2008-10-23
WO2008079674A2 (en) 2008-07-03
JP2010513555A (ja) 2010-04-30
PL2124879T3 (pl) 2017-01-31
ES2657143T3 (es) 2018-03-01
EP2124879A2 (en) 2009-12-02
PL3308769T3 (pl) 2021-07-26

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