DK266289A - Substituerede 2-ethenyl-3,4,5,6-tetrahydrofuro(4,3,2-ef)(3)benzazepinforbindelser, fremgangsmaader til fremstilling heraf samt farmaceutiske midler indeholdende disse - Google Patents

Substituerede 2-ethenyl-3,4,5,6-tetrahydrofuro(4,3,2-ef)(3)benzazepinforbindelser, fremgangsmaader til fremstilling heraf samt farmaceutiske midler indeholdende disse Download PDF

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Publication number
DK266289A
DK266289A DK266289A DK266289A DK266289A DK 266289 A DK266289 A DK 266289A DK 266289 A DK266289 A DK 266289A DK 266289 A DK266289 A DK 266289A DK 266289 A DK266289 A DK 266289A
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Prior art keywords
tetrahydrofuro
ethenyl
procedures
substituted
preparing
Prior art date
Application number
DK266289A
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English (en)
Other versions
DK266289D0 (da
Inventor
John Joseph Lafferty
Robert Michael Demarinis
Joseph Walter Venslavsky
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of DK266289D0 publication Critical patent/DK266289D0/da
Publication of DK266289A publication Critical patent/DK266289A/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK266289A 1988-06-01 1989-05-31 Substituerede 2-ethenyl-3,4,5,6-tetrahydrofuro(4,3,2-ef)(3)benzazepinforbindelser, fremgangsmaader til fremstilling heraf samt farmaceutiske midler indeholdende disse DK266289A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20088488A 1988-06-01 1988-06-01

Publications (2)

Publication Number Publication Date
DK266289D0 DK266289D0 (da) 1989-05-31
DK266289A true DK266289A (da) 1989-12-02

Family

ID=22743610

Family Applications (1)

Application Number Title Priority Date Filing Date
DK266289A DK266289A (da) 1988-06-01 1989-05-31 Substituerede 2-ethenyl-3,4,5,6-tetrahydrofuro(4,3,2-ef)(3)benzazepinforbindelser, fremgangsmaader til fremstilling heraf samt farmaceutiske midler indeholdende disse

Country Status (8)

Country Link
EP (1) EP0344980A3 (da)
JP (1) JPH0232081A (da)
AU (2) AU627729B2 (da)
CA (1) CA1320486C (da)
DK (1) DK266289A (da)
PT (1) PT90718B (da)
WO (1) WO1989012050A1 (da)
ZA (1) ZA894097B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ229296A (en) * 1988-06-01 1991-05-28 Smithkline Beckman Corp 2-substituted-3,4,5,b-tetrahydrofuran(4,3,2-ef)(3) benzazepine derivatives and pharmaceutical compositions
US5470845A (en) * 1992-10-28 1995-11-28 Bristol-Myers Squibb Company Methods of using α-phosphonosulfonate squalene synthetase inhibitors including the treatment of atherosclerosis and hypercholesterolemia
CA2107644A1 (en) * 1992-10-28 1994-04-29 David R. Magnin .alpha.-phosphonosulfonae squalene synthetase inhibitors and methd
US5447922A (en) * 1994-08-24 1995-09-05 Bristol-Myers Squibb Company α-phosphonosulfinic squalene synthetase inhibitors
JP6198715B2 (ja) * 2012-03-06 2017-09-20 武田薬品工業株式会社 三環性化合物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3856910A (en) * 1950-01-10 1974-12-24 Roussel Uclaf Novel thienobenzazepines as anti-depressants
US3649644A (en) * 1969-08-08 1972-03-14 Warner Lambert Co 1 2 3 4 4a 5 6 6a-octahydrobenzofuro (3 2-c)indoles
BE795451A (fr) * 1972-02-23 1973-08-16 Pfizer Agents hypoglycemiants aza indoliques tricycliques
US3950343A (en) * 1973-11-06 1976-04-13 Ayerst, Mckenna And Harrison Ltd. Pyrroloisoquinoline derivatives
JPS57144286A (en) * 1981-03-02 1982-09-06 Takeda Chem Ind Ltd Azepinoindole derivative and its preparation
US4833244A (en) * 1985-04-22 1989-05-23 Hoechst-Rouseel Pharmaceuticals Inc. Ethanobenzazepines
DE3525564A1 (de) * 1985-07-15 1987-02-05 Schering Ag Tricyclische verbindungen mit indolstruktur, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
US4769368A (en) * 1986-02-10 1988-09-06 Smithkline Beckman Corporation 2,3,4,8,9,9A-Hexahydro-4-aryl-1H-indeno(1,7-CD)azepines
DE3630539A1 (de) * 1986-09-08 1988-03-10 Madaus & Co Dr Derivate von 2,3,4,5,6,7-hexahydro-2,7-methano-1,5-benzoxazonin (bzw. -1,4-benzoxazonin), verfahren zu ihrer herstellung und arzneimittel, die diese verbindung enthalten
NZ229296A (en) * 1988-06-01 1991-05-28 Smithkline Beckman Corp 2-substituted-3,4,5,b-tetrahydrofuran(4,3,2-ef)(3) benzazepine derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
AU627729B2 (en) 1992-09-03
AU3769089A (en) 1990-01-05
JPH0232081A (ja) 1990-02-01
WO1989012050A1 (en) 1989-12-14
EP0344980A3 (en) 1991-05-15
DK266289D0 (da) 1989-05-31
CA1320486C (en) 1993-07-20
PT90718A (pt) 1989-12-29
AU3527989A (en) 1990-01-11
EP0344980A2 (en) 1989-12-06
ZA894097B (en) 1990-06-27
PT90718B (pt) 1994-11-30

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