DK2654417T3 - Kuldebeskyttende sammensætninger og anvendelser deraf - Google Patents

Kuldebeskyttende sammensætninger og anvendelser deraf Download PDF

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Publication number
DK2654417T3
DK2654417T3 DK11807839.3T DK11807839T DK2654417T3 DK 2654417 T3 DK2654417 T3 DK 2654417T3 DK 11807839 T DK11807839 T DK 11807839T DK 2654417 T3 DK2654417 T3 DK 2654417T3
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Denmark
Prior art keywords
composition
microorganisms
inositol
derivative
lactobacillus
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DK11807839.3T
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English (en)
Inventor
Christophe Hollard
David Fett
Petersen Lars Wexøe
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Dupont Nutrition Biosci Aps
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/04—Preserving or maintaining viable microorganisms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0221—Freeze-process protecting agents, i.e. substances protecting cells from effects of the physical process, e.g. cryoprotectants, osmolarity regulators like oncotic agents

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  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Claims (13)

1. Sammensætning, der omfatter: (a) mindst ét ikke-reducerende sukker, (b) inositol eller et derivat deraf, hvor derivatet er en inositol, hvori mindst én hydroxylfunktion er blevet modificeret eller substitueret, hvor vægt/vægt-forholdet (a)/ (b) i sammensætningen er fra 1,1 til 1,7, og (c) mikroorganismer.
2. Sammensætning ifølge krav 1, hvor mikroorganismerne er bakterier.
3. Sammensætning ifølge krav 1, hvor mikroorganismerne er mælkesyrebakterier.
4. Sammensætning ifølge krav 1, 2 eller 3, hvor vægt/vægt- forholdet (a)/ (b) er fra 1,3 til 1,7.
5. Sammensætning ifølge et hvilket som helst af kravene 1 til 4, hvor (a) er en blanding af ikke-reducerende sukre.
6. Sammensætning ifølge et hvilket som helst af kravene 1-5, hvor det eller de ikke-reducerende sukre er valgt fra gruppen, der omfatter trehalose, 2,3,2',3'-tetra-0-benzyl-6,6'-di-O-decanoyl-4,4'-bis-0(diphenylphosphono)-alfa,alfa-trehalose, 6. 6'-di-0-decanoyl-4,4'-di-O-phosphono-alfa,alfa-trehalose, 2,3,2',3'-tetra-0-benzyl-4,4'-bis-O-(diphenylphosphono)-alfa,alfa-trehalose-6, 6' , fedtsyreester, saccharose, saccharose-6-benzoat, saccharose-6-acetat, saccharose-6- glutarat og saccharose-6-laurat.
7. Sammensætning ifølge et hvilket som helst af kravene 1 til 4, hvor (a) er trehalose, og (b) er inositol.
8. Sammensætning ifølge krav 3, hvor mælkesyrebakterierne er valgt fra gruppen, der omfatter stammer fra slægten Lactococcus, Lactobacillus, Leuconostoc, Bifidobacterium, Carnobacterium, Enterococcus, Propionibacterium, Pediococcus, Streptococcus og blandinger deraf.
9. Sammensætning ifølge krav 8, hvor mælkesyrebakterierne er valgt fra gruppen, der omfatter stammer fra arten og underarten Bifidobacterium bifidum, Bifidobacterium lactis, Bifidobacterium longum, Bifidobacterium breve, Lactobacillus reuteri, Lactobacillus acidophilus, Lactobacillus casei, Lactobacillus plantarum, Lactobacillus delbruckii bulgaricus, Lactobacillus rhamnosus, Streptococcus thermophilus, Lactococcus lactis, Lactobacillus pentoceus, Lactobacillus buchneri, Lactobacillus brevis, Pediococcus pentosaceus, Pediococcus acidilactici, Pediococcus pervulus, Propionibacterium freudenreichi, Propionibacterium jenseni, Streptococcus salivarius og blandinger deraf.
10. Sammensætning ifølge et hvilket som helst af kravene 1, 2, 3, 8 og 9, hvor sammensætningen omfatter mikroorganismer ved en koncentration på mellem lxlO8 CFU/g sammensætning og 5xl012 CFU/g sammensætning.
11. Sammensætning ifølge et hvilket som helst af kravene 1, 2, 3 og 8-10, hvor sammensætningen omfatter: (a) mindst 4 vægt-% af det ikke-reducerende sukker og (b) mindst 3 vægt-% af inositol eller et derivat deraf.
12. Anvendelse af en sammensætning, der omfatter: (a) mindst ét ikke-reducerende sukker, (b) inositol eller et derivat deraf, hvor derivatet er en inositol, hvori mindst én hydroxylfunktion er blevet modificeret eller substitueret, hvor vægt/vægt-forholdet (a)/ (b) i sammensætningen er fra 1,1 til 1,7, til konservering af mikroorganismer.
13. Fremgangsmåde til konservering af mikroorganismer, der omfatter følgende trin: fremstilling af en sammensætning, der omfatter: (a) mindst ét ikke-reducerende sukker, (b) inositol eller et derivat deraf, hvor derivatet er en inositol, hvori mindst én hydroxylfunktion er blevet modificeret eller substitueret, hvor vægt/vægt-forholdet (a)/ (b) i sammensætningen er fra 1,1 til 1,7, tilsætning af sammensætningen til mikroorganismer til opnåelse af en sammensætning, der omfatter mikroorganismer, - udsættelse af sammensætningen, der omfatter mikroorganismer, for et fryse-, tørre- eller fryse-tørre-trin.
DK11807839.3T 2010-12-23 2011-12-21 Kuldebeskyttende sammensætninger og anvendelser deraf DK2654417T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201061426645P 2010-12-23 2010-12-23
EP10196808 2010-12-23
PCT/US2011/066461 WO2012088261A1 (en) 2010-12-23 2011-12-21 Cryoprotective compositions and uses thereof

Publications (1)

Publication Number Publication Date
DK2654417T3 true DK2654417T3 (da) 2018-10-29

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ID=44802584

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Application Number Title Priority Date Filing Date
DK11807839.3T DK2654417T3 (da) 2010-12-23 2011-12-21 Kuldebeskyttende sammensætninger og anvendelser deraf

Country Status (5)

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US (5) US20140004083A1 (da)
EP (1) EP2654417B1 (da)
DK (1) DK2654417T3 (da)
ES (1) ES2688538T3 (da)
WO (1) WO2012088261A1 (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2729559T3 (da) 2011-07-06 2018-12-10 Dupont Nutrition Biosci Aps Fremgangsmåde til reduktion af viskositeten af en mikroorganismeholdig suspension eller et mikroorganismeholdigt koncentrat
EP2744888B1 (en) 2011-08-18 2017-12-13 Chr. Hansen A/S Method for purifying bacterial cells
WO2014029783A1 (en) 2012-08-20 2014-02-27 Chr. Hansen A/S Method for freeze drying a bacteria-containing concentrate
DK3287518T3 (da) 2012-08-20 2022-02-21 Chr Hansen As Fremgangsmåde til frysetørring af et bakterieholdigt koncentrat
MX2018002278A (es) * 2015-08-31 2018-03-23 Chr Hansen As Bacteria de lactobacillus fermentum con actividad antifungica.
SG11201906748PA (en) 2017-01-31 2019-08-27 Univ Kansas State Microbial cells, methods of producing the same, and uses thereof
US11898184B2 (en) * 2017-09-07 2024-02-13 Sweet Sense Inc. Low glycemic sugar composition
US11814617B2 (en) 2017-10-20 2023-11-14 Kansas State University Research Foundation Methods of producing ensiled plant materials using Megasphaera elsdenii
CN113260256A (zh) 2018-10-26 2021-08-13 丹尼斯科美国公司 稳定的微生物组合物和干燥工艺
BE1027135B1 (fr) 2019-03-21 2020-10-19 Aquatic Science Sa Composition pour optimiser le traitement biologique des piscines
BE1027133B1 (fr) 2019-03-21 2020-10-19 Aquatic Science Sa Procede pour optimiser le traitement biologique des piscines
CN116583182A (zh) 2020-10-06 2023-08-11 丹尼斯科美国公司 易分散的贮存稳定的生物活性颗粒
EP4056053A1 (en) 2021-03-12 2022-09-14 Biogaia AB Pre-conditioning of l. reuteri
EP4056052A1 (en) 2021-03-12 2022-09-14 Biogaia AB Gos pre-conditioning l. reuteri and gos in final formulation
EP4304388A1 (en) 2021-03-12 2024-01-17 Société des Produits Nestlé S.A. Gos pre-conditioning lactobacillus strains and gos in final formulation
CA3216136A1 (en) * 2021-04-30 2022-11-03 Aaron Blake Cowley Compositions for preserving anaerobic microorganisms and methods of making and using the same

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9002003D0 (en) 1990-01-29 1990-03-28 Ici Plc Stabilized cultures of microorganisms
GB9308734D0 (en) 1993-04-28 1993-06-09 Ici Plc Viable bacteria
US6743575B2 (en) 1996-06-14 2004-06-01 Biostore New Zealand Ltd. Compositions and methods for the preservation of living tissues
US5827640A (en) * 1996-06-14 1998-10-27 Biostore New Zealand Limited Methods for the preservation of cells and tissues using trimethylamine oxide or betaine with raffinose or trehalose
FR2813756B1 (fr) * 2000-09-11 2003-03-07 Imv Technologies Dilueur pour la conservation de spermatozoides de porcins
WO2004000335A1 (en) * 2002-06-19 2003-12-31 The Board Of Regents Of The University Of Nebraska Lactic acid bacteria cultures that inhibit food-borne pathogens
CN1259849C (zh) * 2002-06-28 2006-06-21 王建华 青贮专用乳酸菌接种剂及其制造方法
WO2004011616A2 (en) * 2002-07-26 2004-02-05 The General Hospital Corporation Systems and methods for cell preservation
US20050100559A1 (en) * 2003-11-07 2005-05-12 The Procter & Gamble Company Stabilized compositions comprising a probiotic
US20070105186A1 (en) 2005-02-09 2007-05-10 Gibson Berman C Method for preserving microbial cells
EP1973406B1 (en) 2005-12-28 2014-03-12 Advanced Bionutrition Corporation A delivery vehicle for probiotic bacteria comprising a dry matrix of polysaccharides, saccharides and polyols in a glass form
JP5536640B2 (ja) 2007-05-03 2014-07-02 オロフソン、トビアス 新鮮な蜂蜜又はミツバチの蜂蜜産生管から単離された新規細菌
US7888062B1 (en) * 2010-02-01 2011-02-15 Microbios, Inc. Process and composition for the manufacture of a microbial-based product

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Publication number Publication date
US20170369834A1 (en) 2017-12-28
EP2654417A1 (en) 2013-10-30
WO2012088261A1 (en) 2012-06-28
ES2688538T3 (es) 2018-11-05
US20190376023A1 (en) 2019-12-12
US20140004083A1 (en) 2014-01-02
EP2654417B1 (en) 2018-07-11
US20210261908A1 (en) 2021-08-26
US20240263127A1 (en) 2024-08-08

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