DK2607486T3 - KEX2-kløvningsregioner af rekombinante fusionsproteiner - Google Patents
KEX2-kløvningsregioner af rekombinante fusionsproteinerInfo
- Publication number
- DK2607486T3 DK2607486T3 DK13151041.4T DK13151041T DK2607486T3 DK 2607486 T3 DK2607486 T3 DK 2607486T3 DK 13151041 T DK13151041 T DK 13151041T DK 2607486 T3 DK2607486 T3 DK 2607486T3
- Authority
- DK
- Denmark
- Prior art keywords
- fusion proteins
- recombinant fusion
- kex2 cleavage
- cleavage regions
- regions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
- C07K16/462—Igs containing a variable region (Fv) from one specie and a constant region (Fc) from another
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Mycology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/484,814 US20080026376A1 (en) | 2006-07-11 | 2006-07-11 | KEX2 cleavage regions of recombinant fusion proteins |
| EP07861326.2A EP2044202B1 (en) | 2006-07-11 | 2007-06-21 | Kex2 cleavage regions of recombinant fusion proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2607486T3 true DK2607486T3 (da) | 2014-10-20 |
Family
ID=38986752
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK13151041.4T DK2607486T3 (da) | 2006-07-11 | 2007-06-21 | KEX2-kløvningsregioner af rekombinante fusionsproteiner |
| DK13151039.8T DK2607485T3 (da) | 2006-07-11 | 2007-06-21 | KEX2-kløvningsregioner af rekombinante fusionsproteiner |
| DK07861326.2T DK2044202T3 (da) | 2006-07-11 | 2007-06-21 | KEX2-kløvningsregioner af rekombinante fusionsproteiner |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK13151039.8T DK2607485T3 (da) | 2006-07-11 | 2007-06-21 | KEX2-kløvningsregioner af rekombinante fusionsproteiner |
| DK07861326.2T DK2044202T3 (da) | 2006-07-11 | 2007-06-21 | KEX2-kløvningsregioner af rekombinante fusionsproteiner |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US20080026376A1 (da) |
| EP (3) | EP2607486B1 (da) |
| JP (1) | JP5548448B2 (da) |
| CN (2) | CN103805619A (da) |
| BR (1) | BRPI0714432B1 (da) |
| CA (1) | CA2657273C (da) |
| DK (3) | DK2607486T3 (da) |
| ES (3) | ES2523898T3 (da) |
| SI (3) | SI2044202T1 (da) |
| WO (1) | WO2008048378A2 (da) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011507507A (ja) * | 2007-12-21 | 2011-03-10 | フジフィルム・マニュファクチュアリング・ヨーロッパ・ベスローテン・フエンノートシャップ | マルチマー性前駆体のｉｎｖｉｖｏタンパク質分解的プロセシングによる関心対象のタンパク質の分泌収量の改善 |
| GB0908770D0 (en) | 2009-04-24 | 2009-07-01 | Danisco | Method |
| CA2766009A1 (en) * | 2009-06-25 | 2010-12-29 | Danisco A/S | Variant lipolytic enzymes with improved expression, functionality and/or activity |
| EP2494050A4 (en) * | 2009-10-30 | 2013-10-30 | Merck Sharp & Dohme | FACTOR FOR STIMULATING GRANULOCYTES AND MONOCYTES PRODUCED IN GLYCOMODIFIED PICHIA PASTORIS |
| EP2643456B1 (en) | 2010-11-24 | 2016-05-11 | Novartis International Pharmaceutical Ltd. | Fusion enzymes having n-acetylglucosaminyltransferase activity |
| US8846357B2 (en) | 2012-12-20 | 2014-09-30 | E I Du Pont De Nemours And Company | Stabilized chlorine dioxide for contamination control in Zymomonas fermentation |
| CN106030384A (zh) * | 2013-10-08 | 2016-10-12 | 东海光学株式会社 | 用于评价眼镜镜片的评价方法、利用该评价方法设计眼镜镜片的设计方法、和用于计算透过镜片观看物体时受试者的视知觉特性的计算方法 |
| CN108064266A (zh) | 2014-07-21 | 2018-05-22 | 格利科斯芬兰公司 | 在丝状真菌中具有哺乳动物样n-聚糖的糖蛋白的制备 |
| CN113784990A (zh) * | 2019-03-08 | 2021-12-10 | 丹尼斯科美国公司 | 融合多肽 |
| CA3155541A1 (en) * | 2019-11-27 | 2021-06-03 | Ravi Chandra BEERAM | Nucleic acids, vectors, host cells and methods for production of fructosyltransferase from aspergillus japonicus |
| BR112022008663A2 (pt) * | 2019-11-27 | 2022-07-19 | Revelations Biotech Pvt Ltd | Ácidos nucleicos, vetores, células hospedeiras e métodos para a produção de beta-frutofuranosidase de aspergillus niger |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) * | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| CA1338400C (en) | 1983-08-31 | 1996-06-18 | David H. Gelfand | Recombinant fungal cellulases |
| US4797361A (en) * | 1983-10-24 | 1989-01-10 | Lehigh University | Microorganism and process |
| US5364770A (en) * | 1985-08-29 | 1994-11-15 | Genencor International Inc. | Heterologous polypeptides expressed in aspergillus |
| NZ217373A (en) | 1985-08-29 | 1990-10-26 | Genencor Inc | Production of heterologous peptide in filamentous fungi, vectors and dna |
| GB8610600D0 (en) | 1986-04-30 | 1986-06-04 | Novo Industri As | Transformation of trichoderma |
| CA1333777C (en) * | 1988-07-01 | 1995-01-03 | Randy M. Berka | Aspartic proteinase deficient filamentous fungi |
| DK105489D0 (da) * | 1989-03-03 | 1989-03-03 | Novo Nordisk As | Polypeptid |
| CA2097180C (en) * | 1990-12-10 | 2007-08-14 | Timothy Fowler | Saccharification of cellulose by cloning and amplification of the .beta.-glucosidase gene of trichoderma reesei |
| EP1559776A3 (en) | 1994-06-30 | 2006-01-11 | Novozymes Biotech, Inc. | Non-toxic, non-toxigenic, non-pathogenic Fusarium expression system and promoters and terminators for use therein |
| US6265204B1 (en) * | 1997-01-17 | 2001-07-24 | Genencor International, Inc. | DNA sequences, vectors, and fusion polypeptides for secretion of polypeptides in filamentous fungi |
| CN1230546C (zh) | 1998-10-06 | 2005-12-07 | 马克·阿龙·埃马尔法尔布 | 丝状真菌宿主领域的转化系统 |
| US6268328B1 (en) * | 1998-12-18 | 2001-07-31 | Genencor International, Inc. | Variant EGIII-like cellulase compositions |
| CN1451039A (zh) * | 1999-08-13 | 2003-10-22 | 曼彻斯特维多利亚大学 | 肌醇六磷酸酶、编码肌醇六磷酸酶的核酸及包含有此核酸的载体和宿主细胞 |
| EP1214431A1 (en) * | 1999-09-09 | 2002-06-19 | Iogen Bio-Products Corporation | Expression of proteins in genetically modified fungi |
| US7795002B2 (en) * | 2000-06-28 | 2010-09-14 | Glycofi, Inc. | Production of galactosylated glycoproteins in lower eukaryotes |
| EP1487853A4 (en) * | 2002-02-08 | 2006-06-28 | Genencor Int | SECRETION, TRANSCRIPTION AND SPORULATION GENES IN BACILLUS CLAUSII |
| WO2003089614A2 (en) | 2002-04-18 | 2003-10-30 | Genencor International, Inc. | Production of functional antibodies in filamentous fungi |
| WO2005001036A2 (en) | 2003-05-29 | 2005-01-06 | Genencor International, Inc. | Novel trichoderma genes |
| CN1875029B (zh) * | 2003-11-06 | 2010-06-16 | 金克克国际有限公司 | 蛋白酶抑制剂及其变异体在丝状真菌中的表达 |
| BRPI0416762A (pt) * | 2003-11-21 | 2007-02-27 | Genencor Int | expressão de enzimas hidrolisantes de amido granular em trinchoderma e processo para produzir glicose a partir de substratos de amido granular |
| US8097445B2 (en) | 2004-03-25 | 2012-01-17 | Danisco Us Inc. | Exo-endo cellulase fusion protein |
| EP1749092A2 (en) | 2004-05-27 | 2007-02-07 | Genencor International, Inc. | Acid-stable alpha amylases having granular starch hydrolyzing activity and enzyme compositions |
-
2006
- 2006-07-11 US US11/484,814 patent/US20080026376A1/en not_active Abandoned
-
2007
- 2007-06-21 BR BRPI0714432-6A patent/BRPI0714432B1/pt not_active IP Right Cessation
- 2007-06-21 EP EP13151041.4A patent/EP2607486B1/en active Active
- 2007-06-21 CA CA2657273A patent/CA2657273C/en active Active
- 2007-06-21 SI SI200731533T patent/SI2044202T1/sl unknown
- 2007-06-21 EP EP13151039.8A patent/EP2607485B1/en active Active
- 2007-06-21 SI SI200731531T patent/SI2607485T1/sl unknown
- 2007-06-21 DK DK13151041.4T patent/DK2607486T3/da active
- 2007-06-21 CN CN201310576545.2A patent/CN103805619A/zh active Pending
- 2007-06-21 ES ES07861326.2T patent/ES2523898T3/es active Active
- 2007-06-21 WO PCT/US2007/014476 patent/WO2008048378A2/en active Application Filing
- 2007-06-21 ES ES13151039.8T patent/ES2516341T3/es active Active
- 2007-06-21 CN CN200780025987.0A patent/CN101490261B/zh active Active
- 2007-06-21 JP JP2009519442A patent/JP5548448B2/ja active Active
- 2007-06-21 SI SI200731528T patent/SI2607486T1/sl unknown
- 2007-06-21 EP EP07861326.2A patent/EP2044202B1/en active Active
- 2007-06-21 DK DK13151039.8T patent/DK2607485T3/da active
- 2007-06-21 DK DK07861326.2T patent/DK2044202T3/da active
- 2007-06-21 ES ES13151041.4T patent/ES2517524T3/es active Active
-
2012
- 2012-05-15 US US13/472,296 patent/US8518667B2/en active Active
-
2013
- 2013-07-03 US US13/935,337 patent/US8936917B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2657273A1 (en) | 2008-04-24 |
| ES2523898T3 (es) | 2014-12-02 |
| US20080026376A1 (en) | 2008-01-31 |
| SI2607485T1 (sl) | 2014-11-28 |
| JP2009542258A (ja) | 2009-12-03 |
| US20130011877A1 (en) | 2013-01-10 |
| CN101490261A (zh) | 2009-07-22 |
| EP2607486A1 (en) | 2013-06-26 |
| US20140024067A1 (en) | 2014-01-23 |
| DK2607485T3 (da) | 2014-09-29 |
| SI2607486T1 (sl) | 2014-12-31 |
| ES2516341T3 (es) | 2014-10-30 |
| WO2008048378A2 (en) | 2008-04-24 |
| BRPI0714432A2 (pt) | 2013-02-13 |
| SI2044202T1 (sl) | 2014-11-28 |
| US8518667B2 (en) | 2013-08-27 |
| EP2607486B1 (en) | 2014-07-23 |
| EP2044202B1 (en) | 2014-08-20 |
| US8936917B2 (en) | 2015-01-20 |
| ES2517524T3 (es) | 2014-11-03 |
| CA2657273C (en) | 2018-01-16 |
| JP5548448B2 (ja) | 2014-07-16 |
| DK2044202T3 (da) | 2014-10-20 |
| CN101490261B (zh) | 2013-12-18 |
| EP2607485A1 (en) | 2013-06-26 |
| EP2607485B1 (en) | 2014-07-23 |
| EP2044202A2 (en) | 2009-04-08 |
| WO2008048378A3 (en) | 2008-07-10 |
| CN103805619A (zh) | 2014-05-21 |
| BRPI0714432B1 (pt) | 2017-11-21 |
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