DK2600868T3 - Kombination af en pyrroloquinolinforbindelse og et aminoglycosid-antimikrobielt middel - Google Patents

Kombination af en pyrroloquinolinforbindelse og et aminoglycosid-antimikrobielt middel Download PDF

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Publication number
DK2600868T3
DK2600868T3 DK11745813.3T DK11745813T DK2600868T3 DK 2600868 T3 DK2600868 T3 DK 2600868T3 DK 11745813 T DK11745813 T DK 11745813T DK 2600868 T3 DK2600868 T3 DK 2600868T3
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DK
Denmark
Prior art keywords
combination
antimicrobial agent
aminoglycoside antimicrobial
pyrroloquinoline compound
pyrroloquinoline
Prior art date
Application number
DK11745813.3T
Other languages
English (en)
Inventor
Yanmin Hu
Anthony R M Coates
Original Assignee
Helperby Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Helperby Therapeutics Ltd filed Critical Helperby Therapeutics Ltd
Application granted granted Critical
Publication of DK2600868T3 publication Critical patent/DK2600868T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK11745813.3T 2010-08-05 2011-08-05 Kombination af en pyrroloquinolinforbindelse og et aminoglycosid-antimikrobielt middel DK2600868T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1013207.4A GB201013207D0 (en) 2010-08-05 2010-08-05 Novel combination
PCT/GB2011/001182 WO2012017216A1 (en) 2010-08-05 2011-08-05 Combination of a pyrroloquinoline compound and an aminoglycodise antimicrobial agent

Publications (1)

Publication Number Publication Date
DK2600868T3 true DK2600868T3 (da) 2022-05-09

Family

ID=42931259

Family Applications (1)

Application Number Title Priority Date Filing Date
DK11745813.3T DK2600868T3 (da) 2010-08-05 2011-08-05 Kombination af en pyrroloquinolinforbindelse og et aminoglycosid-antimikrobielt middel

Country Status (10)

Country Link
US (1) US9216186B2 (da)
EP (1) EP2600868B1 (da)
JP (1) JP6021268B2 (da)
CA (1) CA2806185C (da)
DK (1) DK2600868T3 (da)
ES (1) ES2912954T3 (da)
GB (1) GB201013207D0 (da)
PL (1) PL2600868T3 (da)
PT (1) PT2600868T (da)
WO (1) WO2012017216A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201107755D0 (en) * 2011-05-10 2011-06-22 Helperby Therapeutics Ltd Novel compounds
WO2016097755A1 (en) * 2014-12-18 2016-06-23 Helperby Therapeutics Limited Antimicrobial combinations and their use in the treatment of microbial infection
GB201518969D0 (en) * 2015-10-27 2015-12-09 Helperby Therapeutics Ltd Triple combination
KR102461715B1 (ko) * 2020-10-12 2022-11-02 대한민국 항균 및 항진균 활성을 나타내는 신균주 페니실리움 비세티 및 이의 용도
CN113528388A (zh) * 2021-07-19 2021-10-22 海南大学 珊瑚共生链霉菌、发酵生产放线菌素d的方法及应用
CN115778974A (zh) * 2022-09-09 2023-03-14 吉林大学 虫草素在制备伤寒沙门氏菌抑制剂中的医用用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE886765A (fr) * 1979-12-26 1981-06-19 Lilly Co Eli Compositions antibiotiques contenant un macrolide et un aminoheteroside
PL177592B1 (pl) 1993-10-22 1999-12-31 Smithkline Beecham Corp Kompozycja farmaceutyczna lub weterynaryjna w postaci kremu
PT1129212E (pt) 1998-11-09 2004-11-30 Helperby Therapeutics Ltd Processo de triagem para agentes antibacterianos
US6974585B2 (en) 2001-08-01 2005-12-13 Medlogic Global Limited Durable multi-component antibiotic formulation for topical use
AU2004262533A1 (en) 2003-08-08 2005-02-17 Ulysses Pharmaceutical Products Inc. Halogenated quinazolinyl nitrofurans as antibacterial agents
KR20070091613A (ko) 2004-11-08 2007-09-11 그렌마크 파머수티칼스 엘티디. 항여드름 화합물 및 항생제 화합물을 함유하는 국소적 제약조성물
GB0522715D0 (en) * 2005-11-08 2005-12-14 Helperby Therapeutics Ltd New use
GB0709513D0 (en) * 2007-05-17 2007-06-27 Helperby Therapeutics Ltd Topical formulations
GB0705915D0 (en) 2007-03-28 2007-05-09 Helperby Therapeutics Ltd New use
DK2182950T3 (da) 2007-05-17 2017-11-06 Helperby Therapeutics Ltd Anvendelse af 4-(pyrrolidin-1-yl)quinolinforbindelser til at dræbe klinisk latente mikroorganismer

Also Published As

Publication number Publication date
EP2600868A1 (en) 2013-06-12
US9216186B2 (en) 2015-12-22
JP2013532717A (ja) 2013-08-19
CA2806185C (en) 2018-11-20
US20130137652A1 (en) 2013-05-30
GB201013207D0 (en) 2010-09-22
PL2600868T3 (pl) 2022-07-25
ES2912954T3 (es) 2022-05-30
JP6021268B2 (ja) 2016-11-09
PT2600868T (pt) 2022-05-13
WO2012017216A1 (en) 2012-02-09
EP2600868B1 (en) 2022-03-09
CA2806185A1 (en) 2012-02-09

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