DK249489A - Therapeutisk virksomme peptider, isaer bombesinantagonistiske og litorinantagonistiske peptider samt fremgangsmaade til fremstilling deraf - Google Patents
Therapeutisk virksomme peptider, isaer bombesinantagonistiske og litorinantagonistiske peptider samt fremgangsmaade til fremstilling deraf Download PDFInfo
- Publication number
- DK249489A DK249489A DK249489A DK249489A DK249489A DK 249489 A DK249489 A DK 249489A DK 249489 A DK249489 A DK 249489A DK 249489 A DK249489 A DK 249489A DK 249489 A DK249489 A DK 249489A
- Authority
- DK
- Denmark
- Prior art keywords
- peptides
- naturally occurring
- peptide
- bombesin
- litorinantagonistic
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 title 2
- 238000000034 method Methods 0.000 title 1
- 108010051479 Bombesin Proteins 0.000 abstract 4
- 102000013585 Bombesin Human genes 0.000 abstract 4
- DNDCVAGJPBKION-DOPDSADYSA-N bombesin Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC=1NC2=CC=CC=C2C=1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H]1NC(=O)CC1)C(C)C)C1=CN=CN1 DNDCVAGJPBKION-DOPDSADYSA-N 0.000 abstract 4
- 238000001727 in vivo Methods 0.000 abstract 2
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000004071 biological effect Effects 0.000 abstract 1
- 238000003776 cleavage reaction Methods 0.000 abstract 1
- 230000002860 competitive effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000007017 scission Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
- C07K7/086—Bombesin; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10057187A | 1987-09-24 | 1987-09-24 | |
| PCT/US1988/003286 WO1989002897A1 (en) | 1987-09-24 | 1988-09-23 | Therapeutic peptides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK249489D0 DK249489D0 (da) | 1989-05-23 |
| DK249489A true DK249489A (da) | 1989-07-20 |
Family
ID=22280431
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK249489A DK249489A (da) | 1987-09-24 | 1989-05-23 | Therapeutisk virksomme peptider, isaer bombesinantagonistiske og litorinantagonistiske peptider samt fremgangsmaade til fremstilling deraf |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0309297B1 (de) |
| JP (1) | JP2795449B2 (de) |
| AT (1) | ATE113961T1 (de) |
| DE (1) | DE3852086T2 (de) |
| DK (1) | DK249489A (de) |
| ES (1) | ES2065336T3 (de) |
| FI (1) | FI100719B (de) |
| NO (1) | NO178306C (de) |
| WO (1) | WO1989002897A1 (de) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5084555A (en) * | 1989-08-21 | 1992-01-28 | The Administrators Of The Tulane Educational Fund | An octapeptide bombesin analog |
| US5877277A (en) * | 1987-09-24 | 1999-03-02 | Biomeasure, Inc. | Octapeptide bombesin analogs |
| AU618029B2 (en) * | 1987-11-02 | 1991-12-12 | Imperial Chemical Industries Plc | Polypeptide compounds |
| GB8808768D0 (en) * | 1988-04-14 | 1988-05-18 | Erba Carlo Spa | Peptide ligands for bombesin receptors |
| GB8813356D0 (en) * | 1988-06-06 | 1988-07-13 | Ici Plc | Polypeptide compounds |
| GB2231051B (en) * | 1989-05-05 | 1992-12-16 | Erba Carlo Spa | Bombesin antagonists |
| CA2045494A1 (en) * | 1989-11-06 | 1991-05-07 | Luigia Gozzini | Reduced irreversible bombesin antagonists |
| NZ236114A (en) * | 1989-11-22 | 1993-04-28 | Merrell Dow Pharma | Peptide antagonists of bombesin and of gastrin releasing peptide, and pharmaceutical compositions |
| US5834433A (en) * | 1990-07-26 | 1998-11-10 | Merrell Pharmaceuticals Inc. | Compounds and pharmaceutical uses of peptides of bombesin and GRP |
| ZA915740B (en) * | 1990-07-26 | 1992-05-27 | Merrell Dow Pharma | Peptides |
| US5244883A (en) * | 1990-11-29 | 1993-09-14 | The Administrators Of The Tulane Educational Fund | Nonapeptide bombesin antagonists |
| US5369094A (en) * | 1990-11-29 | 1994-11-29 | The Administrators Of The Tulane Educational Fund | Polypeptide bombesin antagonists |
| AU659659B2 (en) * | 1991-05-23 | 1995-05-25 | Merrell Dow Pharmaceuticals Inc. | Bombesin analogs |
| JPH07505865A (ja) * | 1992-02-07 | 1995-06-29 | メレルダウファーマスーティカルズ インコーポレイテッド | ボンベシンのフェニルアラニン類似体類 |
| US6492330B1 (en) | 1996-08-16 | 2002-12-10 | National Institute Of Immunology | Antiangiogenic drugs |
| US6156725A (en) * | 1996-08-16 | 2000-12-05 | National Institute Of Immunology | Drug for the treatment of cancer |
| EP0835662B1 (de) * | 1996-10-08 | 2001-11-14 | National Institute of Immunology | Arzneimittel zur Behandlung von Krebs |
| KR100558131B1 (ko) | 1999-03-29 | 2006-03-10 | 더 프록터 앤드 갬블 캄파니 | 멜라노코르틴 수용체 리간드를 함유하는 약제학적 조성물및 멜라노코르틴 수용체 리간드를 함유하는 약제의제조방법 |
| US6316414B1 (en) | 2000-07-31 | 2001-11-13 | Dabur Research Foundation | Somatostatin analogs for the treatment of cancer |
| US8420050B2 (en) | 2003-01-13 | 2013-04-16 | Bracco Imaging S.P.A. | Gastrin releasing peptide compounds |
| US7611692B2 (en) | 2003-01-13 | 2009-11-03 | Bracco Imaging S.P.A. | Gastrin releasing peptide compounds |
| US7922998B2 (en) | 2003-01-13 | 2011-04-12 | Bracco Imaging S.P.A. | Gastrin releasing peptide compounds |
| US7226577B2 (en) | 2003-01-13 | 2007-06-05 | Bracco Imaging, S. P. A. | Gastrin releasing peptide compounds |
| US7850947B2 (en) | 2003-01-13 | 2010-12-14 | Bracco Imaging S.P.A. | Gastrin releasing peptide compounds |
| MXPA05011233A (es) | 2003-04-22 | 2005-12-14 | Conseils De Rech S Et D Aplica | Vectores peptidicos. |
| JP2009503027A (ja) * | 2005-08-03 | 2009-01-29 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | アルツハイマー病ｉｉの治療のための置換エタン−１，２−ジアミン |
| CA2662449A1 (en) * | 2006-09-08 | 2008-03-13 | Bayer Schering Pharma Aktiengesellschaft | Compounds and methods for 18f labeled agents |
| US10240138B2 (en) | 2008-06-12 | 2019-03-26 | Ipsen Bioinnovation Limited | Polypeptides that bind to and inhibit secretion from growth hormone secreting cells |
| CN104328100B (zh) | 2008-06-12 | 2019-08-23 | 益普生生物创新有限公司 | 神经内分泌病的抑制 |
| GB0820970D0 (en) | 2008-11-17 | 2008-12-24 | Syntaxin Ltd | Suppression of cancer |
| EP2198878A1 (de) | 2008-12-18 | 2010-06-23 | University Of Miami | Polypeptide Bombesinantagonisten |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4207311A (en) | 1977-07-18 | 1980-06-10 | The Salk Institute For Biological Studies | Peptides having analgesic and thermoregulative properties |
-
1988
- 1988-09-23 JP JP63509311A patent/JP2795449B2/ja not_active Expired - Fee Related
- 1988-09-23 WO PCT/US1988/003286 patent/WO1989002897A1/en not_active Ceased
- 1988-09-26 DE DE3852086T patent/DE3852086T2/de not_active Expired - Fee Related
- 1988-09-26 EP EP88308916A patent/EP0309297B1/de not_active Expired - Lifetime
- 1988-09-26 ES ES88308916T patent/ES2065336T3/es not_active Expired - Lifetime
- 1988-09-26 AT AT88308916T patent/ATE113961T1/de not_active IP Right Cessation
-
1989
- 1989-05-23 NO NO892060A patent/NO178306C/no unknown
- 1989-05-23 FI FI892507A patent/FI100719B/fi not_active IP Right Cessation
- 1989-05-23 DK DK249489A patent/DK249489A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DE3852086D1 (de) | 1994-12-15 |
| EP0309297A3 (en) | 1990-07-04 |
| EP0309297A2 (de) | 1989-03-29 |
| AU622123B2 (en) | 1992-04-02 |
| JPH02502016A (ja) | 1990-07-05 |
| NO178306C (no) | 1996-02-28 |
| NO892060D0 (no) | 1989-05-23 |
| ES2065336T3 (es) | 1995-02-16 |
| FI100719B (fi) | 1998-02-13 |
| WO1989002897A1 (en) | 1989-04-06 |
| FI892507A0 (fi) | 1989-05-23 |
| DK249489D0 (da) | 1989-05-23 |
| JP2795449B2 (ja) | 1998-09-10 |
| EP0309297B1 (de) | 1994-11-09 |
| DE3852086T2 (de) | 1995-05-18 |
| ATE113961T1 (de) | 1994-11-15 |
| NO892060L (no) | 1989-07-21 |
| FI892507L (fi) | 1989-05-23 |
| NO178306B (no) | 1995-11-20 |
| AU2710288A (en) | 1989-04-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHS | Application shelved for other reasons than non-payment |