DK2447275T3 - Methods and reagents for the treatment of age-related macular degeneration - Google Patents
Methods and reagents for the treatment of age-related macular degeneration Download PDFInfo
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- DK2447275T3 DK2447275T3 DK12152177.7T DK12152177T DK2447275T3 DK 2447275 T3 DK2447275 T3 DK 2447275T3 DK 12152177 T DK12152177 T DK 12152177T DK 2447275 T3 DK2447275 T3 DK 2447275T3
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- cfhr1
- ser
- antibody
- cfhr3
- glu
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| US8012683B2 (en) | 2006-02-13 | 2011-09-06 | University Of Iowa Research Foundation | Variants in complement regulatory genes predict age-related macular degeneration |
| US20080146501A1 (en) * | 2006-02-13 | 2008-06-19 | University Of Iowa Research Foundation | Protective complement proteins and age-related macular degeneration |
| MX2009000909A (es) * | 2006-07-26 | 2009-02-04 | Univ Yale | Diagnostico y tratamiento de degeneracion macular relacionada con la edad. |
| CA2704809A1 (en) * | 2007-11-01 | 2009-05-07 | University Of Iowa Research Foundation | Rca locus analysis to assess susceptibility to amd and mpgnii |
| US20090186370A1 (en) * | 2008-01-18 | 2009-07-23 | Ogle Matthew F | Diagnostic biomarkers for vascular aneurysm |
| DE102008049136B4 (de) * | 2008-09-26 | 2012-10-25 | Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e.V. | Neue Regulatoren des angeborenen Immunsystems |
| JP2012533562A (ja) * | 2009-07-16 | 2012-12-27 | グラクソ ウェルカム マニュファクチュアリング ピーティーイー リミテッド | 治療法 |
| WO2011017229A2 (en) * | 2009-08-06 | 2011-02-10 | Tufts - New England Medical Center | Plasma complement components as expression markers for age-related macular degeneration and related phenotypes |
| WO2011029954A2 (de) * | 2009-09-14 | 2011-03-17 | Mosaiques Diagnostics And Therapeutics Ag | Polypeptidmarker zur diagnostik und beurteilung vaskulärer erkrankungen |
| JP5706612B2 (ja) * | 2009-12-28 | 2015-04-22 | 学校法人 埼玉医科大学 | 加齢黄斑変性症易罹患性の判定マーカー並びに判定方法及び判定キット |
| WO2012051462A2 (en) * | 2010-10-14 | 2012-04-19 | Sequenom, Inc. | Complement factor h copy number variants found in the rca locus |
| WO2012112955A2 (en) * | 2011-02-17 | 2012-08-23 | The Trustees Of Columbia University In The City Of New York | Methods for identifying subjects with a genetic risk for developing iga nephropathy |
| CN103874526A (zh) * | 2011-04-29 | 2014-06-18 | 犹他大学研究基金会 | 预测补体介导的疾病的发展的方法 |
| JP2013064616A (ja) * | 2011-09-15 | 2013-04-11 | Osaka Univ | 高度動脈硬化を発症している可能性を検出する方法およびその利用 |
| WO2013150132A2 (de) * | 2012-04-05 | 2013-10-10 | Mosaiques Diagnostics And Therapeutics Ag | Polypeptidmarker zur diagnostik und beurteilung von schlaganfällen |
| GB201301632D0 (en) * | 2013-01-30 | 2013-03-13 | Imp Innovations | Complement System |
| EP2962106A1 (en) * | 2013-02-26 | 2016-01-06 | Roche Diagnostics GmbH | Agents, kits and methods for complement factor h-related protein 1 detection |
| US10202647B2 (en) | 2013-04-12 | 2019-02-12 | The Trustees Of Columbia University In The City Of New York | Mutations in DSTYK cause dominant urinary tract malformations |
| WO2014194213A1 (en) * | 2013-05-30 | 2014-12-04 | University Of Iowa Research Foundation | Specific complement proteins and efficacy of antibody therapy |
| US10155983B2 (en) | 2014-03-31 | 2018-12-18 | Machaon Diagnostics, Inc. | Method of diagnosis of complement-mediated thrombotic microangiopathies |
| JP7199966B2 (ja) | 2015-12-23 | 2023-01-06 | ソルボンヌ ウニベルシテ | CD11b/CD18に対するCFHの結合を阻害する薬剤、およびその使用 |
| US11142548B2 (en) | 2016-05-10 | 2021-10-12 | Sorbonne Universite | Agents that activate CD47 and their use in the treatment of inflammation |
| WO2019215330A1 (en) * | 2018-05-10 | 2019-11-14 | The University Of Manchester | Methods for assessing macular degeneration |
| EP3824095A4 (en) | 2018-07-20 | 2022-04-20 | University of Utah Research Foundation | GENE THERAPY FOR MACULATE GENERATION |
| DE102018120016B4 (de) | 2018-08-16 | 2020-09-03 | Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e.V. -Hans-Knöll-Institut- | Modulatoren der Funktion von Faktor H-verwandtem Protein 1 und deren Verwendungen in der Kontrolle von Entzündung |
| US20220146530A1 (en) * | 2019-03-07 | 2022-05-12 | Reti Mark Co., Ltd. | A combination of biomarkers for diagnosing of age-related macular degeneration and use thereof |
| CN113966401A (zh) | 2019-04-10 | 2022-01-21 | 犹他大学研究基金会 | 用于治疗amd的htra1调节 |
| KR20230019062A (ko) * | 2019-10-22 | 2023-02-07 | 어플라이드 제네틱스 테크놀로지스 코퍼레이션 | 연령-관련 황반 변성 및 다른 안구 질환 및 장애의 치료를 위한 아데노-연관 바이러스 (aav) 벡터 |
| EP4214515A1 (en) * | 2020-09-16 | 2023-07-26 | Complement Therapeutics Limited | Complementome assay |
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| EP2479284A3 (en) | 2012-08-08 |
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| US20150050646A1 (en) | 2015-02-19 |
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| SG173371A1 (en) | 2011-08-29 |
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| US20180371547A1 (en) | 2018-12-27 |
| US20080152659A1 (en) | 2008-06-26 |
| EP2447275B1 (en) | 2015-04-01 |
| JP5431151B2 (ja) | 2014-03-05 |
| US7867727B2 (en) | 2011-01-11 |
| AU2007272335A1 (en) | 2008-01-17 |
| EP2046807A4 (en) | 2009-10-28 |
| HK1126223A1 (en) | 2009-08-28 |
| EP2046807B1 (en) | 2012-03-28 |
| JP2009544280A (ja) | 2009-12-17 |
| ATE551350T1 (de) | 2012-04-15 |
| EP2479284A2 (en) | 2012-07-25 |
| EP2046807A2 (en) | 2009-04-15 |
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