DK2334827T3 - Metode til kromogen påvisning af to eller flere målmolekyler i en enkelt prøve - Google Patents
Metode til kromogen påvisning af to eller flere målmolekyler i en enkelt prøve Download PDFInfo
- Publication number
- DK2334827T3 DK2334827T3 DK09791784.3T DK09791784T DK2334827T3 DK 2334827 T3 DK2334827 T3 DK 2334827T3 DK 09791784 T DK09791784 T DK 09791784T DK 2334827 T3 DK2334827 T3 DK 2334827T3
- Authority
- DK
- Denmark
- Prior art keywords
- target molecules
- single sample
- chromogenic detection
- chromogenic
- detection
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6841—In situ hybridisation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/581—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/583—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with non-fluorescent dye label
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18975208P | 2008-08-22 | 2008-08-22 | |
| PCT/US2009/054614 WO2010022332A1 (en) | 2008-08-22 | 2009-08-21 | Method for chromogenic detection of two or more target molecules in a single sample |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2334827T3 true DK2334827T3 (da) | 2015-06-15 |
Family
ID=41315279
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK09791784.3T DK2334827T3 (da) | 2008-08-22 | 2009-08-21 | Metode til kromogen påvisning af to eller flere målmolekyler i en enkelt prøve |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US8481270B2 (da) |
| EP (1) | EP2334827B1 (da) |
| JP (1) | JP5703219B2 (da) |
| AU (1) | AU2009282760B2 (da) |
| CA (1) | CA2734783C (da) |
| DK (1) | DK2334827T3 (da) |
| ES (1) | ES2538123T3 (da) |
| WO (1) | WO2010022332A1 (da) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011097248A2 (en) | 2010-02-02 | 2011-08-11 | Ventana Medical Systems, Inc. | Composition and method for stabilizing fluorescent particles |
| US8609354B2 (en) | 2010-03-04 | 2013-12-17 | Olli CARPEN | Method for selecting patients for treatment with an EGFR inhibitor |
| WO2013113707A1 (en) | 2012-02-01 | 2013-08-08 | Ventana Medical Systems, Inc. | System for detecting genes in tissue samples |
| EP3764083A1 (en) | 2013-03-12 | 2021-01-13 | Ventana Medical Systems, Inc. | Digitally enhanced microscopy for multiplexed histology |
| EP3201628B1 (en) | 2014-10-02 | 2020-11-18 | Ventana Medical Systems, Inc. | Polymers and conjugates comprising the same |
| WO2016120440A1 (en) | 2015-01-29 | 2016-08-04 | Ventana Medical Systems, Inc. | Dot detection, color classification of dots and counting of color classified dots |
| WO2016120442A1 (en) * | 2015-01-30 | 2016-08-04 | Ventana Medical Systems, Inc. | Foreground segmentation and nucleus ranking for scoring dual ish images |
| WO2016120441A2 (en) | 2015-01-30 | 2016-08-04 | Ventana Medical Systems, Inc. | Quality metrics for automatic evaluation of dual ish images |
| WO2017034927A1 (en) * | 2015-08-21 | 2017-03-02 | The Regents Of The University Of California | Homoallylamines as formaldehyde-responsive triggers |
| JP6880001B2 (ja) | 2015-08-28 | 2021-06-02 | ヴェンタナ メディカル システムズ， インク． | ケージドハプテンを使用するホルマリン固定パラフィン包埋組織におけるタンパク質近接アッセイ |
| CA3016555A1 (en) | 2016-03-08 | 2017-09-14 | Ventana Medical Systems, Inc. | Multiplexed immunohistochemistry using recombinant antibodies with epitope tags |
| JP7128121B2 (ja) | 2016-06-28 | 2022-08-30 | ヴェンタナ メディカル システムズ， インク． | Ｉｈｃ及びｉｓｈアッセイにおけるシグナル増幅のためのクリックケミストリーの応用 |
| EP3475701B1 (en) | 2016-06-28 | 2023-02-22 | Ventana Medical Systems, Inc. | New colors for chromogenic ihc and ish staining with multi-dye quinone methide and tyramide conjugates |
| EP4060345A1 (en) | 2016-12-19 | 2022-09-21 | Ventana Medical Systems, Inc. | Peptide nucleic acid conjugates |
| JP2021507695A (ja) | 2017-12-18 | 2021-02-25 | ヴェンタナ メディカル システムズ， インク． | ペプチド核酸コンジュゲート |
| CN113423698A (zh) | 2018-09-20 | 2021-09-21 | 文塔纳医疗系统公司 | 基于香豆素的交联剂 |
| JP7500727B2 (ja) | 2019-12-18 | 2024-06-17 | エフ． ホフマン－ラ ロシュ アーゲー | 連続的な標識スキームを使用した合成による配列決定方法 |
| CN115702349A (zh) * | 2020-05-07 | 2023-02-14 | 领先细胞医疗诊断有限公司 | 用于同时检测靶核酸和蛋白质的方法及其试剂盒 |
| US11760169B2 (en) | 2020-08-20 | 2023-09-19 | Denso International America, Inc. | Particulate control systems and methods for olfaction sensors |
| US11760170B2 (en) | 2020-08-20 | 2023-09-19 | Denso International America, Inc. | Olfaction sensor preservation systems and methods |
| US12017506B2 (en) | 2020-08-20 | 2024-06-25 | Denso International America, Inc. | Passenger cabin air control systems and methods |
| US11828210B2 (en) | 2020-08-20 | 2023-11-28 | Denso International America, Inc. | Diagnostic systems and methods of vehicles using olfaction |
| US11636870B2 (en) | 2020-08-20 | 2023-04-25 | Denso International America, Inc. | Smoking cessation systems and methods |
| US11881093B2 (en) | 2020-08-20 | 2024-01-23 | Denso International America, Inc. | Systems and methods for identifying smoking in vehicles |
| US11932080B2 (en) | 2020-08-20 | 2024-03-19 | Denso International America, Inc. | Diagnostic and recirculation control systems and methods |
| US11813926B2 (en) | 2020-08-20 | 2023-11-14 | Denso International America, Inc. | Binding agent and olfaction sensor |
| WO2022152777A1 (en) | 2021-01-15 | 2022-07-21 | F. Hoffmann-La Roche Ag | Storage stable caged haptens |
| WO2024002924A2 (en) | 2022-06-28 | 2024-01-04 | F. Hoffmann-La Roche Ag | Fluorescent dyes with large stokes shift |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1564604A (en) | 1925-06-12 | 1925-12-08 | Chas S Hodges | Water wheel |
| US5008185A (en) * | 1985-11-04 | 1991-04-16 | Cell Analysis Systems, Inc. | Methods and apparatus for the quantitation of nuclear proteins |
| US5595707A (en) | 1990-03-02 | 1997-01-21 | Ventana Medical Systems, Inc. | Automated biological reaction apparatus |
| GB9215710D0 (en) | 1992-07-23 | 1992-09-09 | Inst Of Cancer The Research | Analysis of cells |
| AU3717797A (en) | 1996-07-15 | 1998-02-09 | Children's Medical Center Corporation | Method to co-detect introduced genes and their products |
| US6582962B1 (en) | 1998-02-27 | 2003-06-24 | Ventana Medical Systems, Inc. | Automated molecular pathology apparatus having independent slide heaters |
| US20030211630A1 (en) | 1998-02-27 | 2003-11-13 | Ventana Medical Systems, Inc. | Automated molecular pathology apparatus having independent slide heaters |
| US6296809B1 (en) | 1998-02-27 | 2001-10-02 | Ventana Medical Systems, Inc. | Automated molecular pathology apparatus having independent slide heaters |
| US6573043B1 (en) | 1998-10-07 | 2003-06-03 | Genentech, Inc. | Tissue analysis and kits therefor |
| US6649138B2 (en) | 2000-10-13 | 2003-11-18 | Quantum Dot Corporation | Surface-modified semiconductive and metallic nanoparticles having enhanced dispersibility in aqueous media |
| US20020083888A1 (en) | 2000-12-28 | 2002-07-04 | Zehnder Donald A. | Flow synthesis of quantum dot nanocrystals |
| US6670113B2 (en) | 2001-03-30 | 2003-12-30 | Nanoprobes | Enzymatic deposition and alteration of metals |
| EP1409240B1 (en) | 2001-07-20 | 2012-05-09 | Life Technologies Corporation | Luminescent nanoparticles and methods for their preparation |
| US6949342B2 (en) * | 2001-12-21 | 2005-09-27 | Whitehead Institute For Biomedical Research | Prostate cancer diagnosis and outcome prediction by expression analysis |
| US20040115697A1 (en) * | 2002-08-09 | 2004-06-17 | Doxsey Stephen J. | Cancer diagnostics and prognostics |
| JP4004385B2 (ja) * | 2002-11-07 | 2007-11-07 | 独立行政法人科学技術振興機構 | 二重染色法によるガン検出方法 |
| EP1636586B1 (en) | 2003-06-24 | 2009-07-22 | Ventana Medical Systems, Inc. | Enzyme-catalyzed metal deposition for the enhanced in situ detection of immunohistochemical epitopes and nucleic acid sequences |
| WO2006076371A2 (en) * | 2005-01-10 | 2006-07-20 | Baylor College Of Medicine | Method of quantitative immunohistochemistry and in situ hybridization |
| ES2465465T3 (es) * | 2006-11-01 | 2014-06-05 | Ventana Medical Systems, Inc. | Haptenos, conjugados de haptenos, composiciones de los mismos y método para su preparación y uso |
-
2009
- 2009-08-21 AU AU2009282760A patent/AU2009282760B2/en active Active
- 2009-08-21 JP JP2011524027A patent/JP5703219B2/ja active Active
- 2009-08-21 WO PCT/US2009/054614 patent/WO2010022332A1/en active Application Filing
- 2009-08-21 DK DK09791784.3T patent/DK2334827T3/da active
- 2009-08-21 ES ES09791784.3T patent/ES2538123T3/es active Active
- 2009-08-21 US US13/059,274 patent/US8481270B2/en active Active
- 2009-08-21 CA CA2734783A patent/CA2734783C/en active Active
- 2009-08-21 EP EP09791784.3A patent/EP2334827B1/en active Active
-
2013
- 2013-06-07 US US13/913,128 patent/US20130273540A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ES2538123T3 (es) | 2015-06-17 |
| CA2734783A1 (en) | 2010-02-25 |
| US20130273540A1 (en) | 2013-10-17 |
| AU2009282760B2 (en) | 2013-08-15 |
| JP5703219B2 (ja) | 2015-04-15 |
| WO2010022332A1 (en) | 2010-02-25 |
| EP2334827A1 (en) | 2011-06-22 |
| CA2734783C (en) | 2016-04-19 |
| US8481270B2 (en) | 2013-07-09 |
| EP2334827B1 (en) | 2015-03-11 |
| JP2012500973A (ja) | 2012-01-12 |
| US20110136130A1 (en) | 2011-06-09 |
| AU2009282760A1 (en) | 2010-02-25 |
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