DK223490D0 - Tetralinderivater - Google Patents
TetralinderivaterInfo
- Publication number
- DK223490D0 DK223490D0 DK223490A DK223490A DK223490D0 DK 223490 D0 DK223490 D0 DK 223490D0 DK 223490 A DK223490 A DK 223490A DK 223490 A DK223490 A DK 223490A DK 223490 D0 DK223490 D0 DK 223490D0
- Authority
- DK
- Denmark
- Prior art keywords
- alkyl
- cycloalkyl
- thiophene
- hydrogen
- carbon atoms
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/74—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/31—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
- C07C323/38—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton with the sulfur atom of the thio group bound to a carbon atom of a six-membered aromatic ring being part of a condensed ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17313088A | 1988-03-25 | 1988-03-25 | |
| PCT/US1989/000974 WO1989009050A1 (en) | 1988-03-25 | 1989-03-15 | Therapeutically useful tetralin derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK223490D0 true DK223490D0 (da) | 1990-09-17 |
| DK223490A DK223490A (da) | 1990-09-17 |
Family
ID=22630664
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK223490A DK223490A (da) | 1988-03-25 | 1990-09-17 | Tetralinderivater |
Country Status (14)
| Country | Link |
|---|---|
| EP (2) | EP0334538B1 (de) |
| JP (1) | JP2750187B2 (de) |
| KR (1) | KR970005323B1 (de) |
| AT (1) | ATE82954T1 (de) |
| AU (1) | AU616253B2 (de) |
| CA (1) | CA1331191C (de) |
| DE (1) | DE68903659T2 (de) |
| DK (1) | DK223490A (de) |
| ES (1) | ES2053979T3 (de) |
| FI (1) | FI102893B (de) |
| GR (1) | GR3006983T3 (de) |
| NZ (1) | NZ228392A (de) |
| WO (1) | WO1989009050A1 (de) |
| ZA (1) | ZA891903B (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA899033B (en) * | 1988-12-01 | 1990-09-26 | Merrell Dow Pharma | Phenoxy and phenylthio,amino substituted benzocycloalkane derivatives in the treatment and prevention of drug-resistant protozoal infections |
| IL109647A (en) * | 1989-02-27 | 1997-04-15 | Lilly Co Eli | Intermediate compounds for ring-substituted 2-amino-1, 2, 3, 4-tetra- hydronaphthalenes and 3-aminochromanes |
| ATE172712T1 (de) * | 1989-05-31 | 1998-11-15 | Upjohn Co | Zns-wirksame 8-heterocyclyl-2-aminotetralin derivate |
| US5071875A (en) * | 1989-09-25 | 1991-12-10 | Northwestern University | Substituted 2-amidotetralins as melatonin agonists and antagonists |
| SE8904127D0 (sv) * | 1989-12-07 | 1989-12-07 | Astra Ab | New biocyclic amino-substituted compounds |
| FR2659853A1 (fr) * | 1990-03-22 | 1991-09-27 | Midy Spa | Utilisation de derives 2-aminotetraliniques pour la preparation de medicaments destines a combattre les troubles de la motricite intestinale. |
| EP0450238A1 (de) * | 1990-03-30 | 1991-10-09 | Merrell Dow Pharmaceuticals Inc. | Verbindungen für die Behandlung von Migräne |
| US5096908A (en) * | 1990-05-04 | 1992-03-17 | Eli Lilly And Company | Method of inhibiting gastric acid secretion |
| US5258379A (en) * | 1990-05-04 | 1993-11-02 | Eli Lilly And Company | Method of inhibiting gastric acid secretion with n-arylpiperazines |
| EP0471515B1 (de) * | 1990-08-15 | 1997-03-05 | Eli Lilly And Company | Ring-substituierte 2-Amino-1,2,3,4-tetra-hydronaphthaline, 3-Aminochromane und 3-Aminothiochromane |
| IT1251877B (it) * | 1991-09-26 | 1995-05-26 | Zambon Spa | Processo per la preparazione di 2-ammino-5,6 dimetossi-tetralina |
| JP3100005B2 (ja) * | 1992-07-28 | 2000-10-16 | 雪印乳業株式会社 | ヒト免疫不全ウィルス感染・増殖抑制剤 |
| ATE187436T1 (de) * | 1993-08-06 | 1999-12-15 | Upjohn Co | 2-aminoindane als selektive dopamin-d3-liganden |
| NZ510988A (en) * | 1998-10-07 | 2005-01-28 | Ortho Mcneil Pharm Inc | N-aralkylaminotetralins useful as ligands for the neuropeptide Y5 receptor |
| AU2001228681A1 (en) * | 2000-01-28 | 2001-08-07 | Melacure Therapeutics Ab | Novel aromatic amines and amides acting on the melanocortin receptors |
| EP1453806B1 (de) | 2001-12-03 | 2007-12-19 | F. Hoffmann-La Roche Ag | Aminotetralinderivate, antagonisten von muscarinrezeptoren |
| JP4353803B2 (ja) | 2001-12-03 | 2009-10-28 | エフ．ホフマン−ラ ロシュ アーゲー | ムスカリン受容体アンタゴニストとしての４−ピペリジニルアルキルアミン誘導体 |
| DE10334188B4 (de) * | 2003-07-26 | 2007-07-05 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung von Depressionen |
| DE10334187A1 (de) * | 2003-07-26 | 2005-03-03 | Schwarz Pharma Ag | Substituierte 2-Aminotetraline zur Behandlung von Depressionen |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1017359A (en) | 1972-07-03 | 1977-09-13 | Frederic P. Hauck | Substituted cyclic polymethylene phenols |
| JPS5124508B2 (de) | 1972-08-14 | 1976-07-24 | ||
| DE2752659A1 (de) | 1976-12-07 | 1978-06-08 | Sandoz Ag | Neue tetralinderivate, ihre herstellung und verwendung |
| CH637363A5 (en) | 1977-11-24 | 1983-07-29 | Sandoz Ag | Process for preparing novel 2-aminotetralins |
| DE2803582A1 (de) | 1978-01-27 | 1979-08-02 | Sandoz Ag | Neue tetralinderivate, ihre herstellung und verwendung |
| ZA825142B (en) | 1981-07-23 | 1983-04-27 | Erba Farmitalia | N-imidazolyl derivatives of 1,2,3,j-tetrahydro-naphthalene, indan and 2-substituted-1-chroman, and process for their preparation |
| DE3479314D1 (en) * | 1984-05-22 | 1989-09-14 | Nelson Res & Dev | Substituted 2-aminotetralins and processes for synthesis |
| IL79323A (en) * | 1985-07-10 | 1990-03-19 | Sanofi Sa | Phenylethanolaminotetralines,their preparation and pharmaceutical compositions containing them |
| AU6548286A (en) * | 1985-10-04 | 1987-04-24 | Maggioni-Winthrop S.P.A. | Fused cycloaliphatic aminoalcohols |
| DE3718317A1 (de) * | 1986-12-10 | 1988-06-16 | Bayer Ag | Substituierte basische 2-aminotetraline |
| DE3719924A1 (de) | 1986-12-22 | 1988-06-30 | Bayer Ag | 8-substituierte 2-aminotetraline |
-
1989
- 1989-03-10 CA CA000593340A patent/CA1331191C/en not_active Expired - Fee Related
- 1989-03-13 ZA ZA891903A patent/ZA891903B/xx unknown
- 1989-03-15 EP EP89302533A patent/EP0334538B1/de not_active Expired - Lifetime
- 1989-03-15 DE DE8989302533T patent/DE68903659T2/de not_active Expired - Fee Related
- 1989-03-15 WO PCT/US1989/000974 patent/WO1989009050A1/en active IP Right Grant
- 1989-03-15 JP JP1503368A patent/JP2750187B2/ja not_active Expired - Lifetime
- 1989-03-15 KR KR1019890702193A patent/KR970005323B1/ko not_active IP Right Cessation
- 1989-03-15 AT AT89302533T patent/ATE82954T1/de not_active IP Right Cessation
- 1989-03-15 AU AU32846/89A patent/AU616253B2/en not_active Ceased
- 1989-03-15 EP EP89903628A patent/EP0407416A1/de active Pending
- 1989-03-15 ES ES89302533T patent/ES2053979T3/es not_active Expired - Lifetime
- 1989-03-20 NZ NZ228392A patent/NZ228392A/xx unknown
-
1990
- 1990-09-17 DK DK223490A patent/DK223490A/da unknown
- 1990-09-24 FI FI904696A patent/FI102893B/fi not_active IP Right Cessation
-
1993
- 1993-02-04 GR GR930400233T patent/GR3006983T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GR3006983T3 (de) | 1993-06-30 |
| JPH03503411A (ja) | 1991-08-01 |
| ATE82954T1 (de) | 1992-12-15 |
| EP0334538B1 (de) | 1992-12-02 |
| FI904696A0 (fi) | 1990-09-24 |
| WO1989009050A1 (en) | 1989-10-05 |
| NZ228392A (en) | 1991-11-26 |
| AU616253B2 (en) | 1991-10-24 |
| FI102893B1 (fi) | 1999-03-15 |
| JP2750187B2 (ja) | 1998-05-13 |
| CA1331191C (en) | 1994-08-02 |
| FI102893B (fi) | 1999-03-15 |
| ES2053979T3 (es) | 1994-08-01 |
| DE68903659D1 (de) | 1993-01-14 |
| AU3284689A (en) | 1989-10-16 |
| KR970005323B1 (ko) | 1997-04-15 |
| DK223490A (da) | 1990-09-17 |
| EP0334538A1 (de) | 1989-09-27 |
| EP0407416A1 (de) | 1991-01-16 |
| ZA891903B (en) | 1989-11-29 |
| KR900700088A (ko) | 1990-08-11 |
| DE68903659T2 (de) | 1993-04-22 |
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