DK2220060T3 - Tetrahydrobenzothiazolderivater - Google Patents

Tetrahydrobenzothiazolderivater

Info

Publication number
DK2220060T3
DK2220060T3 DK08845853.4T DK08845853T DK2220060T3 DK 2220060 T3 DK2220060 T3 DK 2220060T3 DK 08845853 T DK08845853 T DK 08845853T DK 2220060 T3 DK2220060 T3 DK 2220060T3
Authority
DK
Denmark
Prior art keywords
tetrahydrobenzothiazole
derivatives
tetrahydrobenzothiazole derivatives
Prior art date
Application number
DK08845853.4T
Other languages
English (en)
Inventor
Holger Stark
Jukka Matti Leppanen
Oliver Saur
Tim Kottke
Michael Peter Hill
Britta Caroline Sasse
Original Assignee
Motac Neuroscience Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Motac Neuroscience Ltd filed Critical Motac Neuroscience Ltd
Application granted granted Critical
Publication of DK2220060T3 publication Critical patent/DK2220060T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • C07D277/68Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK08845853.4T 2007-10-31 2008-10-28 Tetrahydrobenzothiazolderivater DK2220060T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0721332.5A GB0721332D0 (en) 2007-10-31 2007-10-31 Medicaments
PCT/GB2008/003623 WO2009056805A1 (en) 2007-10-31 2008-10-28 Medicaments

Publications (1)

Publication Number Publication Date
DK2220060T3 true DK2220060T3 (da) 2017-01-02

Family

ID=38834564

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08845853.4T DK2220060T3 (da) 2007-10-31 2008-10-28 Tetrahydrobenzothiazolderivater

Country Status (8)

Country Link
US (1) US8389555B2 (da)
EP (1) EP2220060B1 (da)
DK (1) DK2220060T3 (da)
ES (1) ES2603880T3 (da)
GB (1) GB0721332D0 (da)
PL (1) PL2220060T3 (da)
PT (1) PT2220060T (da)
WO (1) WO2009056805A1 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9302989B2 (en) * 2010-11-15 2016-04-05 Abbvie Inc. NAMPT and rock inhibitors
US10874669B2 (en) 2012-11-29 2020-12-29 Wayne State University Neuroprotective agents for treatment of neurodegenerative diseases
EP2925755B1 (en) * 2012-11-29 2021-09-08 Wayne State University Neuroprotective agents for the treatment of neurodegenerative diseases
CN104049475B (zh) * 2014-05-30 2017-12-12 江苏弘汉生物科技有限公司 具有防腐蚀功效的去除剂
EP3495363B1 (en) 2016-07-28 2023-08-23 Shionogi & Co., Ltd Nitrogen-containing condensed ring compounds having dopamine d3 receptor antagonistic effect
MX2020007849A (es) 2018-01-26 2020-09-25 Shionogi & Co Compuesto ciclico condensado que tiene efecto antagonista del receptor de dopamina d3.
WO2019146740A1 (ja) 2018-01-26 2019-08-01 塩野義製薬株式会社 ドーパミンd3受容体拮抗作用を有する環式化合物
US11285147B2 (en) 2018-09-07 2022-03-29 Wayne State University Neuroprotective agents for treatment of neurodegenerative diseases
PL442046A1 (pl) * 2022-08-19 2024-02-26 Uniwersytet Jagielloński (E)-N-cynamoiloaminoalkanole o aktywności hamującej melanogenezę
CN115340508B (zh) * 2022-08-22 2024-06-25 南京医科大学 兼具d2受体激动和nmda受体拮抗作用的化合物及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2731619A1 (fr) 1995-03-14 1996-09-20 Logeais Labor Jacques Compositions pharmaceutiques contenant de la l-etrabamine, leurs utilisations et leurs procedes de preparation
RU2185372C2 (ru) * 1996-05-31 2002-07-20 Фармация Энд Апджон Компани Алкилзамещенные циклические амины в качестве селективных лигандов d3-допамина
WO2002098367A2 (en) 2001-06-07 2002-12-12 Wayne State University Hybrid 2-aminotetralin and aryl-substituted piperazine compounds and their use in altering cns activity
EP1730129B1 (en) * 2004-03-19 2011-01-19 Dipharma Francis S.r.l. Intermediates for the preparation of pramipexole

Also Published As

Publication number Publication date
EP2220060B1 (en) 2016-09-14
EP2220060A1 (en) 2010-08-25
PL2220060T3 (pl) 2017-03-31
WO2009056805A1 (en) 2009-05-07
ES2603880T3 (es) 2017-03-01
US8389555B2 (en) 2013-03-05
GB0721332D0 (en) 2007-12-12
US20110046153A1 (en) 2011-02-24
PT2220060T (pt) 2016-11-25

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