DK221282A - Mikrobiel hybrid promotor/operator, replicerbart udtrykkelsesmedium indeholdende denne og e.coli stamme transformeret med udtrykkelsesmediet - Google Patents

Mikrobiel hybrid promotor/operator, replicerbart udtrykkelsesmedium indeholdende denne og e.coli stamme transformeret med udtrykkelsesmediet Download PDF

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Publication number
DK221282A
DK221282A DK221282A DK221282A DK221282A DK 221282 A DK221282 A DK 221282A DK 221282 A DK221282 A DK 221282A DK 221282 A DK221282 A DK 221282A DK 221282 A DK221282 A DK 221282A
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DK
Denmark
Prior art keywords
expression medium
transformed
operator
hybrid promoter
medium containing
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DK221282A
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English (en)
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DK170477B1 (da
Inventor
Herman Albert De Boer
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Genentech Inc
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27401690&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK221282(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US06/338,397 external-priority patent/US4551433A/en
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of DK221282A publication Critical patent/DK221282A/da
Application granted granted Critical
Publication of DK170477B1 publication Critical patent/DK170477B1/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/72—Expression systems using regulatory sequences derived from the lac-operon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin

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  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
DK221282A 1981-05-18 1982-05-17 Mikrobiel hybrid promotor/operator, vektor og udtrykkelsesvektor indeholdende denne, og E. coli stamme transformeret med udtrykkelsesvektoren, kultur af E. coli stammen og fremgangsmåde til mikrobiel produktion af heterologe polypeptider under anvendelse af kulturen DK170477B1 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US26430681A 1981-05-18 1981-05-18
US26430681 1981-05-18
US32817481A 1981-12-07 1981-12-07
US32817481 1981-12-07
US06/338,397 US4551433A (en) 1981-05-18 1982-01-11 Microbial hybrid promoters
US33839782 1982-01-11

Publications (2)

Publication Number Publication Date
DK221282A true DK221282A (da) 1983-01-07
DK170477B1 DK170477B1 (da) 1995-09-11

Family

ID=27401690

Family Applications (1)

Application Number Title Priority Date Filing Date
DK221282A DK170477B1 (da) 1981-05-18 1982-05-17 Mikrobiel hybrid promotor/operator, vektor og udtrykkelsesvektor indeholdende denne, og E. coli stamme transformeret med udtrykkelsesvektoren, kultur af E. coli stammen og fremgangsmåde til mikrobiel produktion af heterologe polypeptider under anvendelse af kulturen

Country Status (8)

Country Link
EP (1) EP0067540B1 (da)
JP (1) JPH0797990B2 (da)
AU (1) AU553901B2 (da)
CA (1) CA1210347A (da)
DE (1) DE3276330D1 (da)
DK (1) DK170477B1 (da)
IE (1) IE53341B1 (da)
IL (1) IL65775A (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU569043B2 (en) * 1982-09-16 1988-01-21 Benzon Pharma A/S Plasmids with conditional uncontrolled replication behaviour
EP0111814A3 (en) * 1982-12-16 1985-08-14 Mgi Pharma, Inc. The cloning and expression of nucleotide sequences encoding bovine growth hormone
US4912046A (en) * 1983-06-27 1990-03-27 Genentech, Inc. Portable inducible control system
EP0130074B1 (en) * 1983-06-27 1991-02-06 Genentech, Inc. Portable inducible control system, expression vectors containing them, microorganisms transformed with them, and their use in expressing exogenous protein
JPS6087792A (ja) * 1983-09-23 1985-05-17 ジェネックス・コーポレイション 雑種制御領域
US5162216A (en) * 1983-09-23 1992-11-10 Enzon Labs Inc. Hybrid gene regulatory region operable in E. coli
JPS60221091A (ja) * 1983-12-21 1985-11-05 Kyowa Hakko Kogyo Co Ltd 新規プロモ−タ−
AU587176B2 (en) * 1984-02-14 1989-08-10 Mycogen Plant Science, Inc. Transfer vector
US4663281A (en) * 1984-03-22 1987-05-05 Mass Institute Of Technology Enhanced production of proteinaceous materials in eucaryotic cells
EP0165613B1 (en) * 1984-06-22 1992-01-15 Hitachi, Ltd. Process for controlling culture of recombinants
DE3430683A1 (de) * 1984-08-21 1986-03-06 Hoechst Ag, 6230 Frankfurt Synthetische regulationsregion
JPS6196998A (ja) * 1984-10-16 1986-05-15 Mitsubishi Chem Ind Ltd ヒトアポリポプロテインａ−ｉ様蛋白の産生方法
HU194309B (en) * 1984-11-26 1988-01-28 Richter Gedeon Vegyeszet Process for producing expressive vectors
GB8431818D0 (en) * 1984-12-17 1985-01-30 Bujard H Expression control sequence
IT1208514B (it) * 1985-03-19 1989-07-10 Eniricerche Spa Vettori plasmidici ad espressione in escherichia coli e/o bacillussubtilis.
AU582288B2 (en) * 1986-03-07 1989-03-16 Damon Biotech Inc. Vector and method for achieving high level expression in eukaryotic cells
JPS62220192A (ja) * 1986-03-12 1987-09-28 インタ−ナシヨナル・ミネラルズ・アンド・ケミカル・コ−ポレイシヨン ハイブリツド表現ベクタ−、その構造および使用
ATE123526T1 (de) * 1987-08-17 1995-06-15 Hoffmann La Roche Hochreprimierbare expressionskontrollsequenzen.
HU197595B (en) * 1987-09-16 1989-04-28 Richter Gedeon Vegyeszet Process for producing expression vectors
DE68922546T2 (de) * 1988-08-16 1995-11-09 Otsuka Pharma Co Ltd Gen-Regulationskassetten, Expressionsvektoren, die diese enthalten und Mikroorganismen, die mit diesen transformiert sind.
AU4860200A (en) * 1999-04-01 2000-10-23 Monsanto Technology Llc Dna construct for regulating the expression of a polypeptide coding sequence in a transformed bacterial host cell
US20020150979A1 (en) * 2000-10-04 2002-10-17 Naokazu Naitou Process for producing a protein

Also Published As

Publication number Publication date
DE3276330D1 (en) 1987-06-19
DK170477B1 (da) 1995-09-11
IE821174L (en) 1982-11-18
EP0067540B1 (en) 1987-05-13
EP0067540A3 (en) 1984-01-18
EP0067540A2 (en) 1982-12-22
JPH0797990B2 (ja) 1995-10-25
JPS57194790A (en) 1982-11-30
AU553901B2 (en) 1986-07-31
AU8376082A (en) 1982-11-25
IE53341B1 (en) 1988-10-26
IL65775A (en) 1985-05-31
CA1210347A (en) 1986-08-26

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