DK2188373T3 - Proteasestabil cellevægslyserende enzym - Google Patents

Proteasestabil cellevægslyserende enzym

Info

Publication number
DK2188373T3
DK2188373T3 DK08801201.8T DK08801201T DK2188373T3 DK 2188373 T3 DK2188373 T3 DK 2188373T3 DK 08801201 T DK08801201 T DK 08801201T DK 2188373 T3 DK2188373 T3 DK 2188373T3
Authority
DK
Denmark
Prior art keywords
protease
cell wall
stable cell
lysing enzyme
wall lysing
Prior art date
Application number
DK08801201.8T
Other languages
English (en)
Inventor
Holger Grallert
Michael Forchheim
Original Assignee
Hyglos Invest Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP07114785A external-priority patent/EP2028271A1/en
Priority claimed from DE102007061929A external-priority patent/DE102007061929A1/de
Application filed by Hyglos Invest Gmbh filed Critical Hyglos Invest Gmbh
Application granted granted Critical
Publication of DK2188373T3 publication Critical patent/DK2188373T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50Isolated enzymes; Isolated proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/503Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
DK08801201.8T 2007-08-22 2008-08-19 Proteasestabil cellevægslyserende enzym DK2188373T3 (da)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US95735107P 2007-08-22 2007-08-22
EP07114785A EP2028271A1 (en) 2007-08-22 2007-08-22 New proteins for use in human and animal staphylococcus infections
DE102007061929A DE102007061929A1 (de) 2007-12-21 2007-12-21 Proteasestabile Zellwand lysierende Enzyme
US3221108P 2008-02-28 2008-02-28
EP08152096 2008-02-28
DE102008023448 2008-05-14
PCT/DE2008/001378 WO2009024142A2 (de) 2007-08-22 2008-08-19 Proteasestabile zellwand lysierende enzyme

Publications (1)

Publication Number Publication Date
DK2188373T3 true DK2188373T3 (da) 2013-04-08

Family

ID=40052086

Family Applications (2)

Application Number Title Priority Date Filing Date
DK12176321.3T DK2511369T3 (da) 2007-08-22 2008-08-19 Proteasestabile cellevægslyserende enzymer
DK08801201.8T DK2188373T3 (da) 2007-08-22 2008-08-19 Proteasestabil cellevægslyserende enzym

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK12176321.3T DK2511369T3 (da) 2007-08-22 2008-08-19 Proteasestabile cellevægslyserende enzymer

Country Status (5)

Country Link
US (2) US8492519B2 (da)
EP (2) EP2188373B1 (da)
DK (2) DK2511369T3 (da)
ES (2) ES2442667T3 (da)
WO (1) WO2009024142A2 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009248095A1 (en) * 2008-05-14 2009-11-19 Biomerieux S.A. Modified Endolysin Ply511
WO2009150171A1 (en) * 2008-06-10 2009-12-17 Profos Ag Method of treatment of inflammatory diseases
US20120171188A1 (en) * 2008-08-19 2012-07-05 Hyglos Invest Gmbh Artificial Peptidoglycan Lysing Enzymes and Peptidoglycan Binding Proteins
EP2157100A1 (en) * 2008-08-19 2010-02-24 Profos AG Artificial peptidoglycan lysing enzymes and peptidoglycan binding proteins
EP2683816B1 (en) 2011-03-11 2017-05-10 Merz Pharma GmbH & Co. KGaA Method for the determination of botulinum neurotoxin biological activity
WO2016069888A1 (en) 2014-10-29 2016-05-06 University Of Wyoming Compositions and methods for making and using hydrolytic enzymes for degrading polysaccharides made by foodborne pathogenic bacteria
CN106811416B (zh) * 2017-02-24 2020-06-12 中国农业科学院植物保护研究所 水解酶CwlC在芽胞杆菌母细胞裂解中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6432444B1 (en) 1997-10-31 2002-08-13 New Horizons Diagnostics Corp Use of bacterial phage associated lysing enzymes for treating dermatological infections
EP1862080A1 (en) * 2006-05-31 2007-12-05 Ajinomoto Co., Inc. Protease-resistant bacteriocins produced by lactic acid bacteria and their use in livestock

Also Published As

Publication number Publication date
EP2188373B1 (de) 2013-01-02
ES2402337T3 (es) 2013-04-30
US8492519B2 (en) 2013-07-23
EP2188373A2 (de) 2010-05-26
ES2442667T3 (es) 2014-02-12
WO2009024142A2 (de) 2009-02-26
US20130295070A1 (en) 2013-11-07
EP2511369B1 (de) 2013-10-23
DK2511369T3 (da) 2014-01-27
EP2511369A1 (de) 2012-10-17
US20100216711A1 (en) 2010-08-26
WO2009024142A3 (de) 2009-06-18

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