DK214585A - PROCEDURE FOR THE PREPARATION OF IMIDAZORIFAMYCINES - Google Patents
PROCEDURE FOR THE PREPARATION OF IMIDAZORIFAMYCINES Download PDFInfo
- Publication number
- DK214585A DK214585A DK214585A DK214585A DK214585A DK 214585 A DK214585 A DK 214585A DK 214585 A DK214585 A DK 214585A DK 214585 A DK214585 A DK 214585A DK 214585 A DK214585 A DK 214585A
- Authority
- DK
- Denmark
- Prior art keywords
- alkyl
- formula
- image
- carbamoyl
- mono
- Prior art date
Links
Abstract
Process for preparing imidazorifamycins of the formula <IMAGE> in which R is hydrogen or acetyl, and R1 and R2, independently of each other, are hydrogen, (C1-4)-alkyl, benzyloxy, mono- or di-(C1-3)-alkylamino-(C1-4)-alkyl, (C1-3)-alkoxy-(C1-4)-alkyl, hydroxy-(C1-4)-alkyl, cyano, halogen, nitro, mercapto, (C1-4)-alkylthio, phenylthio, carbamoyl, mono- or di-(C1-4)-alkyl-carbamoyl, or R1 and R2, together with two consecutive carbon atoms in the pyridine nucleus, form a benzene ring which is optionally substituted by one or two methyl or ethyl groups. The process comprises reacting rifamycin S of the formula <IMAGE> with a 2-aminopyridine of the formula <IMAGE> in which R1 and R2 have the abovementioned meanings.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT346584 | 1984-05-15 | ||
IT346484 | 1984-05-15 | ||
IT03464/84A IT1199375B (en) | 1984-05-15 | 1984-05-15 | PROCESS FOR THE PREPARATION OF IMIDAZO RIFAMICINE |
IT03465/84A IT1199376B (en) | 1984-05-15 | 1984-05-15 | IMIDAZO-RIFAMICINE PREPARATION PROCESS |
Publications (4)
Publication Number | Publication Date |
---|---|
DK214585D0 DK214585D0 (en) | 1985-05-14 |
DK214585A true DK214585A (en) | 1985-11-16 |
DK160829B DK160829B (en) | 1991-04-22 |
DK160829C DK160829C (en) | 1991-10-07 |
Family
ID=26325399
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK214585A DK160829C (en) | 1984-05-15 | 1985-05-14 | PROCEDURE FOR PREPARING PYRIDO-IMIDAZORIFAMYCINES |
Country Status (9)
Country | Link |
---|---|
AR (1) | AR242795A1 (en) |
AT (1) | AT386829B (en) |
CA (1) | CA1215976A (en) |
DK (1) | DK160829C (en) |
ES (1) | ES8603490A1 (en) |
FI (1) | FI83874C (en) |
GR (1) | GR851146B (en) |
NO (1) | NO164030C (en) |
PT (1) | PT80447B (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITMI20032144A1 (en) | 2003-11-07 | 2005-05-08 | Alfa Wassermann Spa | REFLEXIMINE POLIMORPHIC FORMS, PROCESSES TO OBTAIN THEM AND |
US7906542B2 (en) | 2004-11-04 | 2011-03-15 | Alfa Wassermann, S.P.A. | Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin |
US7902206B2 (en) | 2003-11-07 | 2011-03-08 | Alfa Wassermann, S.P.A. | Polymorphic forms α, β and γ of rifaximin |
PL1698630T3 (en) | 2005-03-03 | 2014-12-31 | Alfasigma Spa | New polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal preparations |
AU2007298733B2 (en) | 2006-09-22 | 2012-11-08 | Cipla Limited | Rifaximin |
US7709634B2 (en) | 2007-09-20 | 2010-05-04 | Apotex Pharmachem Inc. | Amorphous form of rifaximin and processes for its preparation |
CA2745980C (en) | 2008-12-10 | 2017-10-31 | Cipla Limited | Rifaximin complexes |
ITBO20120368A1 (en) | 2012-07-06 | 2014-01-07 | Alfa Wassermann Spa | COMPOSITIONS INCLUDING RIFAXIMINA AND AMINO ACIDS, RIFAXIMINE CRYSTALS DERIVING FROM SUCH COMPOSITIONS AND THEIR USE. |
EP2927235B1 (en) | 2014-03-31 | 2017-02-08 | Euticals S.P.A. | Polymorphic mixture of rifaximin and its use for the preparation of solid formulations |
WO2015159275A2 (en) * | 2014-04-19 | 2015-10-22 | Granules India Limited | An improved process for the preparation of rifamycin derivatives |
HUE050054T2 (en) | 2014-05-12 | 2020-11-30 | Alfasigma Spa | Preparation and use of crystalline form tau of rifaximin solvated with degme |
-
1985
- 1985-04-29 CA CA000480320A patent/CA1215976A/en not_active Expired
- 1985-05-13 PT PT8044785A patent/PT80447B/en unknown
- 1985-05-13 GR GR851146A patent/GR851146B/el unknown
- 1985-05-14 DK DK214585A patent/DK160829C/en not_active IP Right Cessation
- 1985-05-14 FI FI851908A patent/FI83874C/en not_active IP Right Cessation
- 1985-05-14 NO NO851920A patent/NO164030C/en unknown
- 1985-05-14 ES ES543116A patent/ES8603490A1/en not_active Expired
- 1985-05-14 AT AT145085A patent/AT386829B/en not_active IP Right Cessation
- 1985-05-15 AR AR30038685A patent/AR242795A1/en active
Also Published As
Publication number | Publication date |
---|---|
FI851908A0 (en) | 1985-05-14 |
GR851146B (en) | 1985-11-25 |
NO164030C (en) | 1990-08-22 |
FI851908L (en) | 1985-11-16 |
AR242795A1 (en) | 1993-05-31 |
DK160829B (en) | 1991-04-22 |
DK160829C (en) | 1991-10-07 |
FI83874C (en) | 1991-09-10 |
PT80447B (en) | 1987-11-11 |
NO164030B (en) | 1990-05-14 |
ATA145085A (en) | 1988-03-15 |
AT386829B (en) | 1988-10-25 |
PT80447A (en) | 1985-06-01 |
DK214585D0 (en) | 1985-05-14 |
NO851920L (en) | 1985-11-18 |
ES543116A0 (en) | 1986-01-01 |
ES8603490A1 (en) | 1986-01-01 |
CA1215976A (en) | 1986-12-30 |
FI83874B (en) | 1991-05-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PBP | Patent lapsed |