DK2036989T3 - Polynukleotid, der er egnet til enkeltcellebaseret reporterassay tilovervågning af genekspressionsmønstre med høj spatiotemporalopløsning - Google Patents
Polynukleotid, der er egnet til enkeltcellebaseret reporterassay tilovervågning af genekspressionsmønstre med høj spatiotemporalopløsningInfo
- Publication number
- DK2036989T3 DK2036989T3 DK07291093.8T DK07291093T DK2036989T3 DK 2036989 T3 DK2036989 T3 DK 2036989T3 DK 07291093 T DK07291093 T DK 07291093T DK 2036989 T3 DK2036989 T3 DK 2036989T3
- Authority
- DK
- Denmark
- Prior art keywords
- gene expression
- single cell
- cell based
- expression patterns
- reporter assay
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07291093A EP2036989B1 (en) | 2007-09-12 | 2007-09-12 | Polynucleotide suitable for single cell based reporter assay to monitor gene expression patterns with high spatio-temporal resolution |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2036989T3 true DK2036989T3 (da) | 2012-10-22 |
Family
ID=38962162
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK07291093.8T DK2036989T3 (da) | 2007-09-12 | 2007-09-12 | Polynukleotid, der er egnet til enkeltcellebaseret reporterassay tilovervågning af genekspressionsmønstre med høj spatiotemporalopløsning |
DK08804165.2T DK2195457T3 (da) | 2007-09-12 | 2008-09-12 | Enkeltcellebaseret reporterassay til overvågning afgenekspressionsmønstre med høj spatiotemporal opløsning |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK08804165.2T DK2195457T3 (da) | 2007-09-12 | 2008-09-12 | Enkeltcellebaseret reporterassay til overvågning afgenekspressionsmønstre med høj spatiotemporal opløsning |
Country Status (9)
Country | Link |
---|---|
US (1) | US9663833B2 (da) |
EP (2) | EP2036989B1 (da) |
JP (1) | JP2010538628A (da) |
AU (1) | AU2008328177B2 (da) |
CA (1) | CA2699358C (da) |
DK (2) | DK2036989T3 (da) |
ES (2) | ES2391906T3 (da) |
PL (2) | PL2036989T3 (da) |
WO (1) | WO2009065635A1 (da) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8835358B2 (en) | 2009-12-15 | 2014-09-16 | Cellular Research, Inc. | Digital counting of individual molecules by stochastic attachment of diverse labels |
WO2012135730A2 (en) * | 2011-03-30 | 2012-10-04 | Verinata Health, Inc. | Method for verifying bioassay samples |
US8937213B2 (en) | 2011-05-21 | 2015-01-20 | Christopher E. Hopkins | Transgenic biosensors |
CN104364392B (zh) | 2012-02-27 | 2018-05-25 | 赛卢拉研究公司 | 用于分子计数的组合物和试剂盒 |
GB2584364A (en) | 2013-03-15 | 2020-12-02 | Abvitro Llc | Single cell bar-coding for antibody discovery |
KR20230074639A (ko) | 2013-08-28 | 2023-05-30 | 벡톤 디킨슨 앤드 컴퍼니 | 대량의 동시 단일 세포 분석 |
TWI493036B (zh) * | 2013-12-24 | 2015-07-21 | Ind Tech Res Inst | 含一cd54表現之報導系統之免疫細胞的應用以及一經選殖之新穎細胞 |
WO2015103339A1 (en) | 2013-12-30 | 2015-07-09 | Atreca, Inc. | Analysis of nucleic acids associated with single cells using nucleic acid barcodes |
MX2017003382A (es) | 2014-09-15 | 2017-11-20 | Abvitro Llc | Secuenciacion de bibliotecas de nucleotidos de alto rendimiento. |
US10830639B2 (en) | 2014-09-25 | 2020-11-10 | Northwestern University | Devices, methods, and systems relating to super resolution imaging |
US20210166320A1 (en) | 2014-10-06 | 2021-06-03 | State Farm Mutual Automobile Insurance Company | System and method for obtaining and/or maintaining insurance coverage |
US10817949B1 (en) | 2014-10-06 | 2020-10-27 | State Farm Mutual Automobile Insurance Company | Medical diagnostic-initiated insurance offering |
US11574368B1 (en) | 2014-10-06 | 2023-02-07 | State Farm Mutual Automobile Insurance Company | Risk mitigation for affinity groupings |
US10713728B1 (en) | 2014-10-06 | 2020-07-14 | State Farm Mutual Automobile Insurance Company | Risk mitigation for affinity groupings |
US10664920B1 (en) | 2014-10-06 | 2020-05-26 | State Farm Mutual Automobile Insurance Company | Blockchain systems and methods for providing insurance coverage to affinity groups |
ES2836802T3 (es) | 2015-02-27 | 2021-06-28 | Becton Dickinson Co | Códigos de barras moleculares espacialmente direccionables |
WO2016149422A1 (en) * | 2015-03-16 | 2016-09-22 | The Broad Institute, Inc. | Encoding of dna vector identity via iterative hybridization detection of a barcode transcript |
EP4180535A1 (en) | 2015-03-30 | 2023-05-17 | Becton, Dickinson and Company | Methods and compositions for combinatorial barcoding |
WO2016172373A1 (en) | 2015-04-23 | 2016-10-27 | Cellular Research, Inc. | Methods and compositions for whole transcriptome amplification |
JP2016208851A (ja) * | 2015-04-30 | 2016-12-15 | 国立大学法人東北大学 | Tlr刺激物質の検出方法 |
ES2745694T3 (es) | 2015-09-11 | 2020-03-03 | Cellular Res Inc | Métodos y composiciones para normalización de biblioteca de ácido nucleico |
US10301677B2 (en) | 2016-05-25 | 2019-05-28 | Cellular Research, Inc. | Normalization of nucleic acid libraries |
US10640763B2 (en) | 2016-05-31 | 2020-05-05 | Cellular Research, Inc. | Molecular indexing of internal sequences |
US10202641B2 (en) | 2016-05-31 | 2019-02-12 | Cellular Research, Inc. | Error correction in amplification of samples |
JP7091348B2 (ja) * | 2016-09-26 | 2022-06-27 | ベクトン・ディキンソン・アンド・カンパニー | バーコード付きオリゴヌクレオチド配列を有する試薬を用いたタンパク質発現の測定 |
US10415080B2 (en) | 2016-11-21 | 2019-09-17 | Nanostring Technologies, Inc. | Chemical compositions and methods of using same |
WO2018144240A1 (en) | 2017-02-01 | 2018-08-09 | Cellular Research, Inc. | Selective amplification using blocking oligonucleotides |
WO2018226293A1 (en) | 2017-06-05 | 2018-12-13 | Becton, Dickinson And Company | Sample indexing for single cells |
US11365409B2 (en) | 2018-05-03 | 2022-06-21 | Becton, Dickinson And Company | Molecular barcoding on opposite transcript ends |
WO2019213294A1 (en) | 2018-05-03 | 2019-11-07 | Becton, Dickinson And Company | High throughput multiomics sample analysis |
CN112703255A (zh) | 2018-05-14 | 2021-04-23 | 纳米线科技公司 | 化学组合物及其使用方法 |
WO2019222284A1 (en) * | 2018-05-14 | 2019-11-21 | The Broad Institute, Inc. | In situ cell screening methods and systems |
EP3844303A4 (en) * | 2018-08-27 | 2022-06-01 | The Regents of The University of California | REPORTER NUCLEIC ACIDS FOR TYPE V CRISPR-MEDIATED DETECTION |
WO2020072380A1 (en) | 2018-10-01 | 2020-04-09 | Cellular Research, Inc. | Determining 5' transcript sequences |
WO2020097315A1 (en) | 2018-11-08 | 2020-05-14 | Cellular Research, Inc. | Whole transcriptome analysis of single cells using random priming |
CN113195717A (zh) | 2018-12-13 | 2021-07-30 | 贝克顿迪金森公司 | 单细胞全转录组分析中的选择性延伸 |
WO2020154247A1 (en) | 2019-01-23 | 2020-07-30 | Cellular Research, Inc. | Oligonucleotides associated with antibodies |
US11965208B2 (en) | 2019-04-19 | 2024-04-23 | Becton, Dickinson And Company | Methods of associating phenotypical data and single cell sequencing data |
EP4004231A1 (en) | 2019-07-22 | 2022-06-01 | Becton, Dickinson and Company | Single cell chromatin immunoprecipitation sequencing assay |
WO2021092386A1 (en) | 2019-11-08 | 2021-05-14 | Becton Dickinson And Company | Using random priming to obtain full-length v(d)j information for immune repertoire sequencing |
EP4090763A1 (en) | 2020-01-13 | 2022-11-23 | Becton Dickinson and Company | Methods and compositions for quantitation of proteins and rna |
US11661625B2 (en) | 2020-05-14 | 2023-05-30 | Becton, Dickinson And Company | Primers for immune repertoire profiling |
US11932901B2 (en) | 2020-07-13 | 2024-03-19 | Becton, Dickinson And Company | Target enrichment using nucleic acid probes for scRNAseq |
US11739443B2 (en) | 2020-11-20 | 2023-08-29 | Becton, Dickinson And Company | Profiling of highly expressed and lowly expressed proteins |
WO2022132188A1 (en) * | 2020-12-15 | 2022-06-23 | Quantum-Si Incorported | Molecular barcode analysis by single-molecule kinetics |
CN115479923A (zh) * | 2021-05-31 | 2022-12-16 | 北京大学 | 一种基于荧光共振能量转移的活细胞单分子rna标记方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999055886A1 (en) * | 1998-04-24 | 1999-11-04 | Genova Pharmaceuticals Corporation | Function-based gene discovery |
US6203986B1 (en) * | 1998-10-22 | 2001-03-20 | Robert H. Singer | Visualization of RNA in living cells |
US6692965B1 (en) * | 1999-11-23 | 2004-02-17 | Chromocell Corporation | Isolation of living cells and preparation of cell lines based on detection and quantification of preselected cellular ribonucleic acid sequences |
WO2001071042A2 (en) * | 2000-03-23 | 2001-09-27 | Pe Corporation (Ny) | Detection kits, such as nucleic acid arrays, for detecting the expression of 10,000 or more drosophila genes and uses thereof |
ES2301818T3 (es) * | 2002-09-18 | 2008-07-01 | The Trustees Of The University Of Pennsylvania | Composiciones, procedimientos y kits para la deteccion de un antigeno sobre una celula y en una mezcla bilogica. |
US7829278B2 (en) * | 2004-10-28 | 2010-11-09 | Board Of Trustees Of The University Of Illinois | Polynucleotide barcoding |
-
2007
- 2007-09-12 EP EP07291093A patent/EP2036989B1/en not_active Not-in-force
- 2007-09-12 DK DK07291093.8T patent/DK2036989T3/da active
- 2007-09-12 PL PL07291093T patent/PL2036989T3/pl unknown
- 2007-09-12 ES ES07291093T patent/ES2391906T3/es active Active
-
2008
- 2008-09-12 ES ES08804165T patent/ES2392005T3/es active Active
- 2008-09-12 US US12/676,135 patent/US9663833B2/en not_active Expired - Fee Related
- 2008-09-12 JP JP2010524516A patent/JP2010538628A/ja active Pending
- 2008-09-12 DK DK08804165.2T patent/DK2195457T3/da active
- 2008-09-12 CA CA2699358A patent/CA2699358C/en not_active Expired - Fee Related
- 2008-09-12 AU AU2008328177A patent/AU2008328177B2/en not_active Ceased
- 2008-09-12 EP EP08804165A patent/EP2195457B1/en not_active Not-in-force
- 2008-09-12 WO PCT/EP2008/062204 patent/WO2009065635A1/en active Application Filing
- 2008-09-12 PL PL08804165T patent/PL2195457T3/pl unknown
Also Published As
Publication number | Publication date |
---|---|
EP2036989A1 (en) | 2009-03-18 |
CA2699358C (en) | 2017-11-21 |
AU2008328177A1 (en) | 2009-05-28 |
DK2195457T3 (da) | 2012-10-29 |
US20110021369A1 (en) | 2011-01-27 |
EP2195457B1 (en) | 2012-07-25 |
PL2036989T3 (pl) | 2012-12-31 |
US9663833B2 (en) | 2017-05-30 |
AU2008328177B2 (en) | 2015-01-22 |
PL2195457T3 (pl) | 2012-12-31 |
ES2392005T3 (es) | 2012-12-03 |
EP2195457A1 (en) | 2010-06-16 |
JP2010538628A (ja) | 2010-12-16 |
ES2391906T3 (es) | 2012-11-30 |
CA2699358A1 (en) | 2009-05-28 |
WO2009065635A1 (en) | 2009-05-28 |
EP2036989B1 (en) | 2012-07-25 |
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